Monday, December 8, 2025

Recursion rises on new data for asset for polyps

 

  • Recursion Pharmaceuticals (RXRX) is up ~3% Monday after reporting phase 1b/2 data on REC-4881 for familial adenomatous polyposis.
  • Participants in the placebo-controlled study who took the allosteric MEK1/2 inhibitor saw a 43% median reduction in polyps following 12 weeks of treatment and 75% experienced reductions in total polyp burden.
  • In these patients, there was a 53% median reduction in polyps from baseline.
  • Also, 40% of patients (4 out of 10) achieved a ≥1-point improvement in a measure of upper gastrointestinal disease severity.
  • Familial adenomatous polyposis is an inherited genetic condition leading to the development of hundreds of thousands of noncancerous polyps in the colon and rectum.
  • Recursion said that it expects to discuss a registration pathway for REC-4881 in H1 2026.

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.