BridgeBio Reports 2021 Financial Results and Business Update

 –Secured up to $750 million in non-dilutive debt financing in November 2021, extending BridgeBio’s financial runway into 2024

–Dosed first patient in Phase 1/2 trial of investigational gene therapy for congenital adrenal hyperplasia (CAH); initial data readout anticipated in second half of 2022

–Launched clinical collaboration with Amgen to study BBP-398, a potentially best-in-class SHP2 inhibitor, in combination with LUMAKRAS® (sotorasib) in advanced solid tumors with the KRAS G12C mutation

–Established strategic collaboration with Helsinn Group to co-develop and co-commercialize BridgeBio’s novel GPX4 inhibitor in multiple cancer tumor types

–Reported Month 12 topline results from Phase 3 ATTRibute-CM study. Following review of ongoing trial data and reassessment of statistical powering assumptions, ATTRibute-CM will continue to its Month 30 endpoint as planned with topline data expected in mid-2023

–Ended quarter with $787.5million in cash, cash equivalents and marketable securities

https://www.biospace.com/article/releases/bridgebio-pharma-reports-fourth-quarter-and-full-year-2021-financial-results-and-business-update/