Wednesday, March 30, 2022

Immutep Combo Shows Encouraging Antitumor Activity in Metastatic Lung Cancer

 

  • All enrolled patients were 2nd line metastatic non-small cell lung carcinoma (NSCLC) patients that had confirmed progressive disease after prior PD-1 or PD-L1 therapy (PD-X refractory)

  • Encouraging interim Disease Control Rate (DCR) of 36.1% (13/36) and 26% progression free at 6 months

  • 73.7% of evaluable patients (14/19) had tumour shrinkage or tumour growth deceleration compared to pre-study situation

  • Encouraging preliminary Overall Survival (OS) at the 6-month landmark, with a 73% survival rate

  • 5.6% of patients (2/36) had confirmed and durable partial responses, with both patients continuing in the trial for over 9 months and 23 months, well beyond expectations

  • Efti continues to be safe and well tolerated

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