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Tuesday, February 11, 2020

CDC mistakenly clears 13th US coronavirus case

The 13th U.S. coronavirus case was confirmed Feb. 10, though CDC officials initially cleared the patient by mistake, according to a UC San Diego Health statement.
CDC officials said Feb. 9 that four American evacuees — assessed for coronavirus after returning from China — tested negative for the respiratory infection. The patients were discharged and returned to quarantine at Marine Corps Air Station Miramar.
However, on Feb. 10, CDC officials said further testing revealed one of the four patients actually did have the virus, now named “Covid-19,” according to CNBC. The individual returned to UC San Diego Health, along with another evacuee showing possible coronavirus symptoms. Both patients are in isolation and have minimal symptoms.
The infected evacuee left the hospital wearing a mask, and marshals transporting the patient wore protective gear as well, according to a Feb. 10 hospital statement cited by The San Diego Union Tribune. It is not known exactly how long the patient was at the base before officials realized the test result was actually positive.
As of 9 a.m., Feb. 11, there are 43,141 confirmed coronavirus cases and 1,018 related deaths.
https://www.beckershospitalreview.com/quality/cdc-mistakenly-clears-13th-us-coronavirus-case.html

Four Sanofi executives to depart in revamp

Bloomberg reports that four senior executives will be leaving Sanofi (SNY -0.1%) as a consequence of CEO Paul Hudon’s revamp.
Dominique Carouge, EVP, Business Transformation
Kathleen Tregoning, EVP, External Affairs
Dieter Weinand, EVP, Primary Care
Ameet Nathwani, M.D., EVP, Chief Medical Officer and Chief Digital Officer
https://seekingalpha.com/news/3540643-four-sanofi-executives-to-depart-bloomberg

InfuSystem Enters Negative Pressure Wound Therapy Market

InfuSystem Holdings, Inc. (NYSE American: INFU) (“InfuSystem” or the “Company”), a leading national health care service provider, facilitating outpatient care for durable medical equipment (“DME”) manufacturers and health care providers, announced today that it has entered into an agreement whereby it will add Negative Pressure Wound Therapy (“NPWT”) to its Integrated Therapy Service (“ITS”) platform.  As part of the new relationship, InfuSystem’s turnkey solutions will include providing the durable medical equipment, overseeing logistics, biomedical services, and managing third-party billing.
Richard DiIorio, chief executive officer of InfuSystem, said, “We are pleased to announce the addition of NPWT to the Integrated Therapy Services platform, joining our existing therapies, oncology and pain management.  This addition results from a premier global health care services company seeking out InfuSystem and our unique expertise in providing clinic-to-home DME solutions.  The core market to be targeted under the new agreement is U.S. home health care, which as a subset of the broader NPWT market, has an estimated addressable market of $600 million per year.”
“We are excited to collaborate with a Top-10 health care services company on this new therapy and we look forward to a long and successful relationship,” Mr. DiIorio continued.  “As seen with past new business wins, the nature of our ITS business involves an initial period of on-boarding the participating facilities.  We will soon begin that on-boarding, but we do not expect to see meaningful revenue from NPWT until the second half of this year.  It should be noted that NPWT was not part of the Company’s previously announced full-year 2020 financial guidance.  We plan to update this guidance in the coming quarters,” concluded Mr. DiIorio.
Negative Pressure Wound Therapy (“NPWT”) is a therapeutic technique using vacuum dressing to promote healing of acute and chronic wounds.  Examples of acute wounds treated include those from surgery and c-sections, and chronic wounds treated include pressure ulcers, trophic, and vascular ulcers.  The U.S. market for NPWT therapy is estimated to exceed $2 billion by 2024.
https://finance.yahoo.com/news/infusystem-enters-negative-pressure-wound-113010550.html

Caterpillar reopens most Chinese facilities

Caterpillar (CAT +1.8%) is one of today’s top gainers on the Dow Jones after the company reopened most of its facilities in China after receiving approval from the local government following the coronavirus outbreak.
None of CAT’s factories are in the worst affected province, but the company had delayed reopening by a week after the Lunar New Year; China accounts for ~10% of Caterpillar’s global sales.
Industrial names in general are performing well today: DE +1.3%, CMI +1.1%.
https://seekingalpha.com/news/3540633-caterpillar-reopens-chinese-facilities

Natera teams up with Elicio in pancreatic cancer study

Cell-free DNA testing services provider Natera (NTRA -0.2%) will collaborate with Cambridge, MA-based Elicio Therapeutics on a Phase 1/2 clinical trial evaluating the latter’s therapeutic cancer vaccine candidate ELI-002 for the adjuvant treatment of patients with pancreatic ductal adenocarcinoma, the most common type of pancreatic cancer, who have undergone neoadjuvant chemo followed by pancreatectomy (removal of the pancreas).
Natera will use its ctDNA platform, Signatera, to select eligible patients whose tumors harbor a mutant KRAS allele and are at high risk for relapse because they have detectable molecular residual disease (MRD) post-surgery. It will also use Signatera to assess the proportion of patients achieving MRD clearance throughout the study.
Elicio plans to file an IND for the 108-subject trial in H1.
https://seekingalpha.com/news/3540626-natera-teams-up-elicio-in-pancreatic-cancer-study

NMC Health down 11% on bearish Muddy Waters report

Ultra-thinly traded NMC Health (OTCPK:NMHLY -11%) is down, albeit on only 5,878 shares, on the heels of the latest bearish report from Muddy Waters (MW) who cites its confusing disclosures about shareholder ownership and other misstatements.
https://seekingalpha.com/news/3540627-nmc-health-down-11-on-bearish-mw-report

Genprex up 29% on license for diabetes gene therapy

Nano cap Genprex (GNPX +28.6%) is up on more than double normal volume in reaction to its agreement with the University of Pittsburgh for exclusive rights to a gene therapy for the potential cure of type 1 and type 2 diabetes.
The gene therapy acts by reprogramming alpha cells in the pancreas into beta-like cells, restoring their function and increasing insulin levels.
The company plans to pursue development partners globally.
Financial terms are not disclosed.
https://seekingalpha.com/news/3540550-genprex-up-29-on-license-for-diabetes-gene-therapy