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Sunday, November 7, 2021

Kaiser Permanente's hospital-at-home push prioritizes savings over high-quality care: nurses union

 Kaiser Permanente has been among the more vocal champions of hospital-at-home programs over the last several months.

In May, the California system headlined a $100 million strategic investment into at-home acute care company Medically Home and, along with Mayo Clinic, announced it would be massively scaling up its early deployments of the startup’s services across its markets.

Just a few weeks back, the partners recruited nearly a dozen other health systems to launch the Advanced Care at Home Coalition. The advocacy group said it would be petitioning Capitol Hill to extend telehealth, remote and in-home care flexibilities enabled by the COVID-19 public health emergency.

Kaiser and other supporters of the shift to in-home acute care say the tech-enabled strategy can limit strain on hospitals, reduce costs and drive better outcomes among patients who are able to recover in the comfort of their own homes.

Thursday, however, Kaiser and its hospital-at-home strategy caught flak from a national nurses union that said it is “completely opposed” to what they see as a play to maximize revenue and limit the need for registered nurses during care delivery.  

“Nurses are horrified by Kaiser’s attempts to redefine what constitutes a hospital and what counts as nursing care,” National Nurses United (NNU) wrote in a statement.

“Not only does this program endanger the imminent safety and lives of patients, it completely undermines the central role registered nurses play in the hands-on care that patients need to safely heal and recover. … We reject Kaiser’s assertion that iPads, cameras, monitors and the occasional visit by likely lesser-skilled and unlicensed personnel are in any way comparable to the skilled, expert nursing care and social-emotional support we [registered nurses] provide every moment of every shift,” the union wrote.

The hospital-at-home trend extends beyond Kaiser alone. According to NNU, at least 82 health systems running 186 hospitals across 33 states are currently allowed to operate and bill Medicare for at-home acute care arrangements.

Still, the union shined its spotlight on Kaiser, which it said is striving to be “at the forefront in normalizing” a delivery model they say will not achieve the positive outcomes its advocates are promising.

“Kaiser and the hospital industry will claim that these programs … have as-good-as-or-better outcomes than patients cared for in a regular hospital setting,” NNU wrote, “but we are skeptical of these small, selective, limited studies and suspect that these rosy outcomes are largely the result of cherry-picking the healthiest patients with the least complications and that such outcomes could not be maintained once these programs are scaled up to include high-acuity, complex cases.”

NNU wrote that the primary driver for these programs is not to improve patient care or satisfaction but “the revelatory idea” that they will be able to shift hospital overhead costs onto the patient by sending them home.

“This model will prove to be a gold mine for Kaiser and the rest of the hospital industry as long as payers such as the Centers for Medicare and Medicaid Services reimburse them at the same rates that traditional hospital care commands,” NNU wrote.

Successfully lobbying to make COVID-19 telemedicine waivers permanent would provide “lucrative revenue” to hospitals, the union wrote, ultimately leading organizations to shutter inpatient services and limit their need for registered nurses.

“Brick-and-mortar rural hospitals, already an endangered species, will certainly go extinct,” NNU wrote.

In a statement provided to Fierce Healthcare, Kaiser said its Advanced Care at Home Program does not limit the role of hospital nurses, who “will continue to play a critically important and highly valued role at Kaiser Permanente.”

Further, the system stressed that its program does not compromise the quality of care being delivered by the organization.

“Regardless of whether the patients are receiving care in the comfort of their own home or in a hospital, we hold ourselves to the same high standard of care. The program empowers multidisciplinary care teams to provide the right care at the right time meeting our patients where they want to be," the health system said in its statement.

NNU contended that placing the burden of patient care on individuals or their family members has previously been shown to cause infections. Similarly, the hospital industry “already has the power to mitigate” hospital-acquired infections and similar preventable conditions without removing patients from the hospital altogether, the union wrote.

NNU also raised concerns that hospital-at-home programs could heighten racial disparities in care. Those with better housing, resources, family and social networks will likely fare better in these programs than the underserved, the group wrote, meaning any financial pressure to enroll patients in the lower-cost program could lead to worse outcomes.

Kaiser noted in its response that patients “must meet established clinical and safety criteria” to be enrolled in its current Advanced Care at Home program.

NNU closed out its condemnation statement with a plea to the public and to private and government payers not to support hospital-at-home programs and to instead “invest in the proven healthcare infrastructure and [registered nurse] workforce we know we need.”

Although Kaiser and its partners have claimed their fair share of hospital-at-home headlines, support for the programs has come from other sources as well.

Back in March, Amazon, Intermountain Healthcare and Ascension kicked off the Moving Health Home coalition that similarly looks to win policymakers over to the value of a “Hospital without Walls.”

Recent months have seen a flurry of partnership and acquisition deals focused on the space. Home recovery care services and technology company Contessa was purchased by Amedisys for $250 million over the summer and launched a new program with Henry Ford Health System about a month back.

https://www.fiercehealthcare.com/hospitals/kaiser-permanente-s-hospital-at-home-push-prioritizes-savings-over-high-quality-care

Saturday, November 6, 2021

NYRR outlines COVID-19 safety guidelines for 2021 TCS NYC Marathon

 The New York Road Runners on Wednesday announced its health and safety guidelines for the 2021 TCS New York City Marathon on November 7.


Since September of 2020, NYRR has safely produced more than 25 road races by effectively implementing health and safety protocols.

To ensure all those involved have a best-in-class experience, the guidelines outline the entire runner experience - from runners picking up their bibs, to the start, running on course, and crossing the finish line.

The following guidelines were established in collaboration with city, state, and federal guidelines and under the guidance of medical and public health experts.

--Face Coverings: All individuals will be required to wear face coverings on public transportation to the start, in the start area on Staten Island, in the post-finish area in Central Park, and in designated indoor venues. It is strongly recommended that all individuals wear face coverings where social distancing isn't possible. Runners are NOT required to wear face coverings on course.

--Vaccinations and Testing: All registered participants will be required to show proof of at least one dose of a COVID-19 vaccine authorized by the Emergency Use Authorization by the U.S. Food & Drug Administration (FDA) or on the World Health Organization (WHO) Emergency Use lists, or proof of a negative COVID-19 test administered no more than 48 hours before November 7. Accepted vaccinations and proof of negative COVID-19 test can be found by CLICKING HERE.

--Density Reduction: This year's marathon will feature a modified race field of approximately 30,000 runners. To further reduce crowd density and increase spacing, an extended range of wave start times will be implemented, with the first wave starting a half hour earlier and later waves extending a half hour later. An additional wave has been added, making a total of five waves.

--Limiting Touchpoints: To reduce crowd gatherings, the following protocols will be implemented:
*Prior to race day, runners have the option of pre-checking a bag. Their pre-checked bag will be available for pick up at the finish area on race day. There will be no bag check on race day.
*To reduce crowding at hydration and fueling stations, runners are allowed self-hydration including hydration or fuel belts. No over-the-shoulder packs are permitted.
*Recovery amenities including a face covering will be pre-bagged and distributed at the finish area to reduce gatherings.
*After finishing, runners will be able to exit Central Park earlier than in the past, on West 72nd Street. There will not be a post-finish family reunion area.

--Hand Sanitizing Stations: Stations will be located at the start, on course, and in post-finish areas.

--Enhanced Cleaning and Disinfection: Enhanced cleaning and disinfecting protocols, with increased frequency, will be instituted in public areas.

Furthermore, NYRR will reduce capacity at all indoor venues.

Bib pickup will take place from November 4 to 6 at the TCS New York City Marathon Expo Presented by New Balance at the Jacob K. Javits Convention Center. In accordance with the Javits Center's policies, face coverings and proof of vaccination will be required to enter the Expo.

Runners who cannot provide proof of vaccination will be able to pick up their bibs at an outdoor location.

Additionally, to reduce crowding at the Expo, runners will pre-select a date and time to pick up their bibs and may bring one guest.

Troops who refuse COVID vaccines won’t be guaranteed veterans benefits, officials warn

 Troops who refuse the coronavirus vaccine won’t see any extra protections or leniency in how their dismissals are handled, Defense and Veterans Affairs officials confirmed Wednesday.

Instead, decisions on whether to give those individuals other-than-honorable discharges — potentially blocking them from a host of veterans benefits — will be left to local commanders, and their cases won’t receive any preferential evaluations for veterans’ benefits eligibility, despite recent lobbying from Republicans lawmakers for a less punishing approach.

“We see the vaccine as a readiness issue,” said Gil Cisneros, Defense Department undersecretary for personnel, during testimony before the Senate Veterans’ Affairs Committee. “Any discharge decision is up to the individual service as to how they proceed with that.”

Earlier on Wednesday, Air Force and Space Force officials announced that about 8,500 airmen missed the Nov. 2 deadline to get the coronavirus vaccine. That represents about 3 percent of the services’ total personnel.

The other military services have similar deadlines in coming weeks.

Cisneros acknowledged concerns from a small portion of the active-duty force about the vaccines but said officials are steadfast in their belief the mandate is needed. As such, the department does not plan to put any special programs or dispensation in place for individuals dismissed for refusing the shots.

VA Deputy Secretary Donald Remy said that those cases will be evaluated by department benefits officials to weigh “mitigating or extenuating circumstances, performance and accomplishments during their service, the nature of the infraction and the character of their service at the time of their discharge.”

That’s standard operation for all veterans, and the department is not planning to handle vaccine refusals in a separate or different way.

Individuals with honorable discharges will be eligible for things like GI Bill benefits, VA home loans and transition assistance programs. Individuals with other-than-honorable discharges are still guaranteed mental health care services through VA, but may be blocked from most other benefits.

In September, House lawmakers approved language in their draft of the annual defense authorization bill that would block military officials from issuing dishonorable discharges to troops who refuse vaccines, arguing that it was too severe of a punishment for the offense.

However, that measure still needs to survive negotiations with Senate lawmakers before becoming law, likely in late December.

Conservative lawmakers have speculated that thousands of troops could be facing dismissal from the ranks before then.

At least 71 service members have died from complications related to coronavirus since the start of the pandemic 20 months ago. None of the troops who died were fully vaccinated.

Among Veterans Affairs patients, at least 16,157 have died from virus complications since March 2020.

https://www.militarytimes.com/news/pentagon-congress/2021/11/03/troops-who-refuse-covid-vaccines-wont-be-guaranteed-veterans-benefits-officials-warn/

Alabama Gov. Ivey signs employee vaccine mandate exemption, parental consent bills

 Gov. Kay Ivey today signed into law a bill prohibiting employers from firing employees who refuse a COVID-19 vaccination if those employees claim a medical or religious exemption.

Ivey signed another bill requiring parental consent for minors, age 18 and under, to receive a COVID-19 vaccination, an exception to the state law that allows minors 14 and older to consent to medical treatments.

The Legislature passed both bills last night, with the Republican majority passing them over opposition from Democrats.

Ivey had previously said she believed that courts, not legislation, were the best way to challenge President Biden’s mandate. Today, she said the state legislation was part of that effort.

“Last week, when I issued my executive order to fight the overreaching Biden vaccine mandates, I reiterated that as long as I am your governor, the state of Alabama will not force anyone to take the covid-19 vaccine,” the governor said. “From the moment the White House rolled out their scare tactic plans to try to force this vaccine on Americans, I called it for what it is: an un-American, outrageous overreach. Alabamians – including those like myself who are pro-vaccine – are adamantly against this weaponization of the federal government, which is why we simply must fight this any way we know how. That is exactly why I have signed Senate Bills 9 and 15 into law. This is another step in the fight, but we are not done yet.

“From issuing the executive order to joining governors in Georgia, South Carolina and other states in suing the Biden Administration, we are doing everything we can to try to get this decision to the U.S. Supreme Court where, hopefully, this overreach will be stopped dead in its tracks. If the Biden Administration presses on with these mandates, the country’s economy will suffer for it. Alabamians – and all Americans – should not have to choose between putting food on the table and getting this shot. I will continue doing everything I can as your governor to fight this thing every step of the way. Alabama will not stand idly by and allow the Biden Administration to get away with this.”

Democrats who opposed the vaccine mandate exemption said it would hurt businesses and undermine efforts to protect employees and customers from the virus.

“The real shock was seeing Alabama Republicans support anti-business legislation like SB9, which will have a big negative impact on communities like Huntsville and Mobile that rely on federal contracting dollars,” House Minority Leader Anthony Daniels, D-Huntsville, said in a press release this morning. “After supporting a bill like that, I don’t think they can say they are pro-business or pro-growth. Hopefully, the business community will remember that House Democrats support their interests.”

The Business Council of Alabama opposed the exemption bill, saying it would put employers in a difficult situation. BCA Interim Executive Director Robin Stone told lawmakers Wednesday that federal contractors are required to follow the federal mandate and failure to do so could cost thousands of jobs in Alabama.

Senate Majority Leader Greg Reed, R-Jasper, said the legislation was to protect freedom and came in response to concerns from people opposed to being forced to take a shot to keep their jobs.

“The Biden administration’s vaccine mandates are a reckless federal government overreach that infringe on Alabamians’ liberty and freedom of personal choice, and could cause significant economic harm to Alabama and Americans across the country,” Reed said. “The legislature has heard from concerned Alabamians across our state who are desperately seeking protection from these unconstitutional mandates, and we have answered with a legislative result to prevent Alabamians from having to make a choice between getting a vaccination they don’t want and maintaining their livelihoods and personal freedoms. I strongly support the Attorney General’s efforts to fight this in the courts, but Alabamians need help now, and the legislation passed today gives Alabamians this much-needed relief.”

The law takes effect immediately. It directs the Alabama Department of Labor to adopt within 21 days an emergency rule allowing employees who are turned down in a request for an exemption to appeal.

Employees would have seven days to appeal to an administrative law judge, who would make a decision within 30 days. The administrative law judge’s decision could then be appealed in circuit court. Employers could not fire an employee for refusing to take the vaccine while the appeal is pending.

The new law says it does not affect the authority of employers to fire employees for any reasons other than refusing a COVID vaccine.

The new law does is not restricted to Biden’s mandate. It does not mention the federal mandate or limit the definition of employer to any certain category.

The law will expire in May 2023 unless the Legislature passes another bill to extend it.

The law, SB 9 by Sen. Chris Elliott, R-Fairhope, would create a standard form allowing employees to choose one of these reasons for an exemption:

  • Health care provider recommended refusal of the vaccine because of health conditions or medications. (A licensed health care provider’s signature is required for this reason only.)
  • Previously suffered a severe allergic reaction, such as anaphylaxis, to a vaccination.
  • Previously suffered a severe allergic reaction to receiving polyethylene glycol or products containing that.
  • Previously suffered a severe allergic reaction to polysorbate or products containing polysorbate.
  • Have received monoclonal antibodies or convalescent plasma to treat COVID-19 in the last 90 days.
  • Have a bleeding disorder or am taking blood thinners.
  • Severely immunocompromised such that the vaccine would cause a health risk.
  • Diagnosed with COVID-19 in the past 12 months.
  • Receiving the vaccine conflicts with sincerely held religious beliefs, practices, or observances.
  • Employees who filled out and signed the form would be presumed to be entitled to the exemption. Rep. Mike Jones, R-Andalusia, an attorney who handled the bill in the House, said the only determining factor in whether the exemption would apply is if the form was properly submitted.

The new law requiring parental consent for minors to receive COVID-19 vaccines does not apply to any other vaccinations or medical treatments.

https://www.al.com/news/2021/11/alabama-gov-kay-ivey-signs-business-vaccine-mandate-exemption-parental-consent-bills.html

Delta variant: Why vaccines alone are not enough

 

  • Researchers conducted a study to investigate the transmissibility of the SARS-CoV-2 Delta variant among vaccinated individuals in the same household.
  • They found that while vaccinated individuals may be less likely to get the infection, they are just as likely to pass on the virus if they contract it.
  • The researchers also found evidence that vaccine protection may wane after 2–3 months of being vaccinated.
  • They conclude that vaccines alone are insufficient to contain the Delta variant, people should maintain non-pharmacological precautions such as mask-wearing, and those eligible for booster shots should get them promptly.

COVID-19 vaccinations significantly reduceTrusted Source a person’s chance of developing adverse outcomes and dying from SARS-CoV-2 infection.

In England, researchTrusted Source has also found that getting fully vaccinated reduces transmission of the Alpha variant by 40–50% in households.

The same study found that if they acquire the infection, individuals also have a lower viral load in their upper respiratory tract than those who are unvaccinated.

However, the Delta variant (B.1.617.2) has replaced the Alpha variant as the dominant variant worldwide. Current vaccines remain highly effectiveTrusted Source at preventing hospitalization and death from infection with the Delta variant.

But vaccines are less effectiveTrusted Source against the Delta variant than against the Alpha variant. The Delta variant also continues to cause a large number of cases in countries with both low and high vaccine coverage.

There has so far been little research into the risk of community transmission of the Delta variant from vaccinated people with mild infections. Understanding this could help policymakers improve guidelines to curb the COVID-19 pandemic.

Recently, researchers led by Imperial College London and the University of Oxford collaborated on a study investigating the transmissibility of the Delta variant among vaccinated individuals within households.

“Understanding the extent to which vaccinated people can pass on the Delta variant to others is a public health priority,” says Dr. Anika Singanayagam, co-lead author of the study. “By carrying out repeated and frequent sampling from contacts of COVID-19 cases, we found that vaccinated people can contract and pass on infection within households, including to vaccinated household members.”

She adds: “Our findings provide important insights into the effect of vaccination in the face of new variants, and specifically, why the Delta variant is continuing to cause high COVID-19 case numbers around the world, even in countries with high vaccination rates. Continued public health and social measures to curb transmission – such as mask-wearing, social distancing, and testing — thus remain important, even in vaccinated individuals.”

The study appears in The Lancet Infectious DiseasesTrusted Source.

Between September 2020 and September 2021, the researchers identified 621 participants via the National Health Service (NHS) Test and Trace, the contact tracing system in the United Kingdom.

These included 19 cases of initial infection and 602 people who either lived with or had contact with symptomatic individuals with confirmed COVID-19 status. Children as young as 5 years old were able to participate with parental consent. However, the cohort’s median age was 36 years old.

Each participant underwent daily PCR tests for 14–20 days to track the progression of their infection. This allowed the researchers to detect changes over time in their viral load, or the amount of virus in a person’s nose and throat, and enable comparisons between fully vaccinated, partially vaccinated, and unvaccinated individuals.

The researchers detected SARS-CoV-2 RNA in 163 (26%) participants, and whole-genome sequencing of PCR-positive cases confirmed that 71 had contracted the Delta variant, 42 the Alpha variant, and 50 had pre-Alpha variant infections.

All of the participants had mild symptoms or were asymptomatic, and the proportion of asymptomatic cases was similar among all participants, whether vaccinated, partially vaccinated, or unvaccinated.

Among 205 individuals who had household contact with those confirmed to have the Delta variant, 53 tested positive for COVID-19.

A quarter of household contacts who had received two doses of the vaccine acquired infection with the Delta variant, while the same was true for 38% of unvaccinated household contacts.

The researchers estimated that vaccines were 34% effective – regardless of symptoms – at preventing transmission of the Delta variant in household settings.

The average time interval between vaccination and study recruitment for fully vaccinated individuals with PCR-positive results was 101 days. For fully vaccinated individuals with PCR-negative results, it was 64 days. This, say the researchers, suggests that immune protection from vaccines may wane in as little as 2–3 months following vaccination.

“Vaccines are critical to controlling the pandemic, as we know they are very effective at preventing serious illness and death from COVID-19,” says Professor Ajit Lalvani, co-lead author of the study. “However, our findings show that vaccination alone is not enough to prevent people from being infected with the Delta variant and spreading it in household settings.”

He continues: “The ongoing transmission we are seeing between vaccinated people makes it essential for unvaccinated people to get vaccinated to protect themselves from acquiring infection and severe COVID-19, especially as more people will be spending time inside in close proximity during the winter months. We found that susceptibility to infection increased already within a few months after the second vaccine dose, so those eligible for COVID-19 booster shots should get them promptly.”

The researchers also found that among those who acquired any variant of COVID-19, viral load declined most rapidly among those who were fully vaccinated and least quickly among those who were unvaccinated. They noted, however, that vaccinated people recorded similar peak viral loads to unvaccinated people.

The speed at which vaccinated people can reduce their viral load explains how being vaccinated reduces hospitalization. However, similar peak viral loads demonstrate how the variant can still spread despite vaccination, as a high viral load indicates a higher level of transmissibility.

“It’s been known for a few months now that fully vaccinated people can become infected within the household setting, something attributable to both waning immunity – against infection much more so than disease – and the circulation of the more transmissible Delta variant,” Dr. John P. Moore, a professor of microbiology and immunology at Weill Cornell Medical College, not involved in the study, told Medical News Today. He went on:

“The results [of this study] don’t seem particularly surprising, but they add to what’s known. Thus, within households, virus spread can occur even if everyone is vaccinated, but less so (by approximately 50%) than when the household members are unvaccinated. One reason for the difference is that viral loads decline more rapidly from the peak in the vaccinated people, reducing the chances of onward transmission.”


Dr. Moore told us: “One caveat when extrapolating to the [United States] is that only 14 of the 38 Delta breakthrough infections in vaccinated people involved the Pfizer vaccine. The rest had received [the Oxford–AstraZeneca vaccine] (23) or the [Sinovac vaccine] (1), which are both less effective than the mRNA vaccines that predominate in this country. Hence, here, I would expect the vaccination benefit to be greater than the numbers reported in this U.K. study.”

The researchers conclude that vaccines alone are insufficient to prevent the spread of the Delta variant in households. They say that both vaccination and non-pharmacological interventions like mask-wearing will remain crucial for containing the pandemic.

One limitation to the study is how the researchers defined who may have contracted SARS-CoV-2 first in a household. It is possible that another member of the household may have had the infection before the person whom the tracking system identified.

Another limitation is that as older people received vaccinations before younger people in the U.K., any age-related findings may be skewed.

“This study confirms that whether vaccinated or not, once a person is infected with COVID, they can [pass it on] to others. Vaccinated people who develop COVID are likely less [prone to pass it on], though,” Dr. Jorge Luis Salinas, an assistant professor of medicine at Stanford University, not involved in the study, told Medical News Today.

When asked what the study means for people deciding how best to protect themselves and their families, Dr. Salinas said: “Vaccines work. They prevent infections. When an infection happens in a vaccinated person, they likely have and spread less virus than unvaccinated people.”

https://www.medicalnewstoday.com/articles/delta-variant-is-vaccination-enough-to-protect-against-transmission

New antibody for COVID-19 and variants ID'd

 A research collaboration between scientists at Duke University and the University of North Carolina at Chapel Hill has identified and tested an antibody that limits the severity of infections from a variety of coronaviruses, including those that cause COVID-19 as well as the original SARS illness.

The antibody was identified by a team at the Duke Human Vaccine Institute and tested in animal models at UNC-Chapel Hill. Researchers published their findings Nov. 2 in the journal Science Translational Medicine.

“This antibody has the potential to be a therapeutic for the current epidemic,” said co-senior author Dr. Barton Haynes, director of DHVI. “It could also be available for future outbreaks, if or when other coronaviruses jump from their natural animal hosts to humans.”

Haynes and colleagues at DHVI isolated the antibody by analyzing the blood from a patient who had been infected with the original SARS-CoV-1 virus, which caused the SARS outbreak in the early 2000s, and from a current COVID-19 patient.

They identified more than 1,700 antibodies, which the immune system produces to bind at specific sites on specific viruses to block the pathogen from infecting cells. When viruses mutate, many binding sites are altered or eliminated, leaving antibodies ineffectual. But there are often sites on the virus that remain unchanged despite mutations. The researchers focused on antibodies that target these sites because of their potential to be highly effective across different lineages of a virus.

Of the 1,700 antibodies from the two individuals, the Duke researchers found 50 antibodies that had the ability to bind to both the SARS-CoV-1 virus as well as SARS-CoV-2, which causes COVID-19.

Further analysis found that one of those cross-binding antibodies was especially potent – able to bind to a multitude of animal coronaviruses in addition to the two human-infecting pathogens.

“This antibody binds to the coronavirus at a location that is conserved across numerous mutations and variations,” Haynes said. “As a result, it can neutralize a wide range of coronaviruses.”

With the antibody isolated, the DHVI team turned to researchers at UNC who have expertise in animal coronaviruses. The UNC-Chapel Hill team, led by co-senior author Ralph S. Baric, epidemiology professor at UNC Gillings School of Global Public Health, tested it in mice to determine whether it could effectively block infections, or minimize the infections that occurred.

They found that it did both. When given before the animals were infected, the antibody protected mice against developing SARS, COVID-19 and its variants such as Delta, and many animal coronaviruses that have the potential to cause human pandemics.

“The findings provide a template for the rational design of universal vaccine strategies that are variant-proof and provide broad protection from known and emerging coronaviruses,” Baric said.

When given after infections, the antibody reduced severe lung symptoms compared to animals that were not treated with the antibody.

“The therapeutic activity even after mice were infected suggests that this could be a treatment deployed in the current pandemic, but also stockpiled to prevent the spread of a future outbreak or epidemic with a SARS-related virus,” said David Martinez, a post-doctoral researcher in the Department of Epidemiology at UNC’s Gillings School.

“This antibody could be harnessed to prevent maybe SARS-CoV-3 or SARS-CoV-4,” Martinez said.

Study principals include Priamvada Acharya, co-senior author along with Haynes and Baric, and Alexandra Schäfer, Sophie Gobeil, Dapeng Li, who were co-lead authors with Martinez. The full list of authors includes Gabriela De la Cruz, Robert Parks, Xiaozhi Lu, Maggie Barr, Victoria Stalls, Katarzyna Janowska, Esther Beaudoin, Kartik Manne, Katayoun Mansouri, Robert J. Edwards, Kenneth Cronin, Boyd Yount, Kara Anasti, Stephanie A. Montgomery, Juanjie Tang, Hana Golding, Shaunna Shen, Tongqing Zhou, Peter D. Kwong, Barney S. Graham, John R. Mascola, David. C. Montefiori, S. Munir Alam, Gregory D. Sempowski, Surender Khurana, Kevin Wiehe and Kevin O. Saunders.

https://www.unc.edu/posts/2021/11/02/scientists-identify-new-antibody-for-covid-19-and-variants/