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Saturday, July 2, 2022

North Korea Blames 'Alien Things' From South For COVID-19 Outbreak

 North Korea said Friday it had discovered the source of its ongoing outbreak of COVID-19: residents who came into contact with “alien things” along its border with South Korea.

The country’s state media said North Korean health authorities believe the outbreak began when two people — an 18-year-old soldier and 5-year-old child — were exposed to the virus by balloons. Pyongyang said the balloons were flown from South Korea, a deeply unlikely method of transmission but one experts say is in line with the North’s efforts to keep up the antagonistic relationship between the two nations, Yonhap News reported.

The country issued a directive that authorities “vigilantly deal with alien things coming by wind and other climate phenomena and balloons in the areas along the demarcation line and borders.”

Activists in South Korea have flown balloons across the border with North Korea to distribute propaganda leaflets. But the South Korean government quickly moved to say even if balloons had reached the north, there is no chance they may have spread the virus, The Associated Press reports.

The country, which had largely succeeded in keeping the coronavirus at bay by effectively sequestering itself from the rest of the world, announced its first official COVID-19 case on May 12. Experts say cases have since exploded across the nation, which is largely unvaccinated against the virus.

North Korea has now reported about 4.7 million cases of fever, but only a small fraction of those have been identified as COVID-19. The nation says just 73 people have died from the disease, an extremely low fatality rate that would be unlikely given North Korea’s health system.

The country’s leader, Kim Jong Un, has described the coronavirus outbreak as the greatest “turmoil to fall on our country since the founding,” according to state media.

Still, North Korea on Thursday rejected offers of humanitarian aid from the United States. The country’s foreign ministry said any offers were merely a “scheme to realize a foul political purpose,” Yonhap reported. (The Washington Post notes the country is suspected to have received some aid from China).

“The U.S. is trying to evade the international society’s criticism by speaking of humanitarian aid while attempting to isolate and squeeze us to death,” state media said.

Omicron-specific COVID shots could increase protection as boosters: European regulators

 Coronavirus vaccines tweaked to include the Omicron variant strain can improve protection when used as a booster, the European Medicines Agency and other global health regulators said on Friday.

Following a meeting on Thursday, the EMA said global regulators had agreed on key principles for updating COVID-19 shots to respond to emerging variants.

While the existing coronavirus vaccines continue to provide good protection against hospitalization and death, the group said, vaccine effectiveness has taken a hit as the virus has evolved.

As such, an Omicron-specific or bivalent booster - meaning a vaccine that includes both the new strain and the original coronavirus strain - could "increase and extend" protection, a statement from the EMA said.

The statement refers specifically to the mRNA vaccines. Both Pfizer Inc and Moderna Inc have been testing retooled versions of their vaccines to include the Omicron variant.

Vaccines which include other variants, for example the Beta variant, might also be considered for use as boosters if clinical trial data demonstrate an adequate level of neutralization against Omicron and other variants of concern, the statement said.

It follows guidance from the World Health Organization that Omicron-specific boosters could restore protection against emerging strains of the coronavirus.

But it stops short of the position of the regulator in the United States, the Food and Drug Administration (FDA), which said on Thursday that it would seek the inclusion specifically of the newer BA.4 and BA.5 strains of Omicron, currently driving a surge in new infections globally, in any new shots for use domestically.

On Tuesday, the head of a WHO advisory committee that has considered the modified shots said the group preferred BA.1-based boosters, arguing that the variant is more distinct and could generate a broader response than the more recently circulating subvariants.

Top U.S. FDA official Peter Marks said in an interview that regulators from other countries were seriously considering using new boosters based on the BA.1 Omicron variant that caused the massive surge in cases last winter, because those shots can be available sooner than the BA.4/5 based booster the United States plans to use.

The EMA said it would provide more details in coming days.

https://www.ctvnews.ca/health/coronavirus/omicron-specific-covid-shots-could-increase-protection-as-boosters-european-regulators-1.5971024

Biden predicts states will ban women from traveling for abortion

 President Joe Biden on Friday predicted some states will try to prevent women from crossing state lines to seek an abortion but pledged to protect women's rights to travel to seek such services.

He said the federal government will also protect women seeking the abortion pill from another state if their home state bans the medication.

The U.S. Supreme Court voted June 24 to overturn the 1973 landmark ruling of Roe vs. Wade, which legalized abortion nationwide. Biden, who called it "a terrible, extreme decision" Friday, reiterated his pledge to protect women's ability to travel across state lines to obtain abortion services.

"As I said last week: This is not over," Biden said Friday. "Last week, I announced two specific actions. First, that if extremist governors try to block a woman from traveling from her state that prohibits her from seeking medical help she needs, to a state that provides care, the federal government will act to protect her bedrock right through the attorney general's office," he said.

Biden also repeated his call for Americans to vote more Democrats into Congress in the upcoming midterm elections. He's seeking to have federal abortion rights codified into law, but in order to do so, Democratic senators would have to get past the filibuster, which would block the legislation from passing with a simple majority.

"The choice is clear: We either elect federal senators and representatives who will codify Roe or Republicans ... who will try to ban abortions nationwide," he said.

https://www.upi.com/Top_News/US/2022/07/01/President-Joe-Biden-abortion-governors/2671656702553/

Friday, July 1, 2022

Agnelli's Exor to invest 833 million euros for 10% stake in France's Institut Merieu

 

Italy's Agnelli family will invest 833 million euros ($865 million) through its holding company Exor to buy a 10% stake in French privately-held healthcare group Institut Merieux, the companies said in a joint statement on Friday.

The deal marks the first major international move into the healthcare business for Exor, which will soon have 9 billion euros ($9.6 billion) to invest after the closing of the sale of Bermuda-based reinsurer Partner Re, expected soon.

Exor will acquire the stake in Institut Merieux - which controls five companies in different healthcare businesses, including Paris-listed bioMerieux - through a reserved capital increase.

The deal is expected to be completed during the summer.

https://www.marketscreener.com/quote/stock/BIOMERIEUX-37839085/news/Agnelli-s-Exor-to-invest-833-million-euros-for-10-stake-in-France-s-Institut-Merieux-40879021/

U.S. abortion ruling ignites retail interest in women contraceptive makers

 

Retail investors have flocked to small biotech firms that make women contraceptives after the U.S. Supreme Court last week overturned the Roe v. Wade ruling that recognized the constitutional right to abortion, Vanda Research said on Friday.

The landmark decision has turned the spotlight on contraception access and led to a temporary spike in demand for over-the-counter emergency contraceptive pills.

Evofem Biosciences and Agile Therapeutics Inc have been biggest beneficiaries, Vanda Research data shows, drawing on average $775,000 and $660,400 in retail inflows in the days following the ruling. That compares with a daily average of $15,540 and $10,320 for the stocks from their IPOs before the ruling on June 24.

"We have seen a surge in retail investor buying in these names on the back of the U.S. abortion ruling, with Agile and Evofem increasing most significantly relative to historical averages," said Lucas Mantle, analyst at Vanda Research.

(Graphic: Retail investor interest in women contraceptive makers, https://fingfx.thomsonreuters.com/gfx/mkt/gkplgeeywvb/U39VQ-retail-investor-interest-in-women-contraceptive-makers%20(1).png)

Since the ruling, Evofem shares have more than doubled in value, while Agile gained as much as 34% to Wednesday's close. Agile's shares have since tumbled more than 40% after the company announced a public offering.

Evofem sells a non-hormonal contraception gel called Phexxi and Agile offers a weekly birth control transdermal patch, sold under the brand name Twirla in the United States.

Phexxi, which was approved in 2020, brought in sales of $4.3 million for Evofem in the latest reported quarter and the company expects revenue of $30 million to $35 million for the year.

Femasys and Dare Bioscience have also captured investors' attention, data from Vanda, an analytics firm that tracks retail flows, show.

Dare Bioscience is developing a non-hormonal contraceptive, while Femasys is developing Femabloc, a permanent birth control product. Both are currently in clinical trials.

https://www.marketscreener.com/quote/stock/AGILE-THERAPEUTICS-INC-16529373/news/U-S-abortion-ruling-ignites-retail-interest-in-women-contraceptive-makers-Vanda-40879191/

Google to delete location history of visits to abortion clinics

 Alphabet Inc's Google will delete location data showing when users visit an abortion clinic, the online search giant said on Friday, following concern that a digital trail could inform law enforcement if an individual terminates a pregnancy illegally.

As state laws limiting abortions set in after the U.S. Supreme Court decided last month that they are no longer guaranteed by the constitution, the technology industry has fretted police could obtain warrants for customers’ search history, geolocation and other information revealing pregnancy plans.

Google on Friday said it will continue to push back against improper or overly broad demands for data by the government, without reference to abortion.

The company said the location history of a Google account is off by default.

Effective in the coming weeks, for those who do use location history, entries showing sensitive places including fertility centers, abortion clinics and addiction treatment facilities will be deleted soon after a visit.

A Google spokesperson did not immediately answer how the company would identify such visits or whether all related data would be wiped from its servers.

Separately, the company on Friday updated its policy to designate U.S. advertisers as providing abortions even if they dispense pills by mail after a virtual consultation, but lack their own facilities. 

https://www.marketscreener.com/quote/stock/ALPHABET-INC-24203373/news/Google-to-delete-location-history-of-visits-to-abortion-clinics-40880995/

Cut Health Insurance for Risky Activities? MD/JD Weighs In

 Welcome to Ethics Consult -- an opportunity to discuss, debate (respectfully), and learn together. We select an ethical dilemma from a true, but anonymized, patient care case, and then we provide an expert's commentary.

Last week, you voted on whether it's ethical for the government to cut health insurance for risky activities.

Cut health insurance for risky activities?

Yes: 63%

No: 37%

And now, bioethicist Jacob M. Appel, MD, JD, weighs in.

Life insurers generally charge a premium for high-risk behaviors. According to a 2013 article in U.S. News & World Report, hunters pay an additional $500 annual premium, and rock climbers pay $1,500 extra; scuba diving and skydiving can add $2,500 to one's rates. Health insurers do not always dig as deeply into the personal behavior of policyholders, but some refuse to cover individuals engaged in dangerous activities. In 2006, one major Illinois corporation reportedly sent letters to its employees informing them that any motorcycle-related injuries would result in immediate termination of their health insurance. In contrast, Medicare and Medicaid usually cover all injuries of their clients, regardless of the origins of those injuries.

The primary reason that public health-insurance entities do not exclude these risk-takers is that health insurance no longer functions as insurance -- at least, not in the traditional sense. As political historian Edward N. Beiser observed in the article "The Emperor's New Scrubs" (1994), "health insurance" is a misnomer. The underlying principle behind traditional insurance is the distribution or "pooling" of risk. Although the odds of my house burning down are quite low, the odds of somebody's home catching fire are reasonably high, and fire insurance evenly distributes the cost of this burden. Everyone pays in; a few unlucky victims receive compensation. In contrast, the vast majority of Americans will eventually experience injuries or illnesses beyond the age of 65, so nearly all of us will withdraw resources from Medicare. Rather than an insurance program, Medicare is a resource management program, through which, in theory, workers fork over their money to the government, which stores it for them and returns it later to pay for their medical expenses (although the reality is that current payroll taxes pay for today's elderly, while future workers will supposedly pay for today's workers to receive coverage).

Since Medicare and Medicaid are default systems for healthcare coverage -- filling in for the poor and elderly where private insurance historically did not pay -- refusing insurance for high-risk behaviors will leave a pool of injured patients without any way to pay for emergency treatment. As a result of a federal statute, the Emergency Medical Treatment and Labor Act of 1986 (EMTALA), hospitals cannot legally turn such patients away. Moreover, even if hospitals could legally opt out of this care, refusing services in an urgent setting is morally indefensible. So rather than deterring conduct or conserving resources, Senator Cheapside's approach would likely just shift the price tag for such care to hospitals, which would then pass this cost along to consumers through higher medical bills.

Another possible problem with Senator Cheapside's proposal is that it may save Medicare and Medicaid less money than he anticipates. Few people who have incomes low enough to qualify to receive Medicaid are likely engaged in beekeeping, bungee jumping, or many of the other expensive activities that concern him. Nor are many elderly Americans, who benefit from Medicare, hang gliding for sport. By far the greatest preventable expenditures for the healthcare system are those related to more mundane risks -- namely obesity and cigarette smoking. Arguably, one might deter smoking and excessive eating by refusing to pay for medical conditions resulting from this conduct. Yet that approach would punish overeaters and addicts for health woes that may prove beyond their control and might even sentence them to worsening illness or death.

Jacob M. Appel, MD, JD, is director of ethics education in psychiatry and a member of the institutional review board at the Icahn School of Medicine at Mount Sinai in New York City. He holds an MD from Columbia University, a JD from Harvard Law School, and a bioethics MA from Albany Medical College.

https://www.medpagetoday.com/opinion/ethics-consult/99546