Search This Blog

Monday, March 4, 2024

Teen bites, slashes NYC hospital workers in rampage days after cut loose from jail

 An unhinged teen viciously attacked six health care workers during a Staten Island hospital rampage over the weekend — just three days after he was released in Brooklyn court for allegedly snatching a woman’s purse, authorities said. 

Devonte Loyce, 19, was being evaluated as an “emotionally disturbed person” at Richmond University Medical Center around 4 a.m. Sunday when he lashed out with a knife at a group of security guards, nurses, emergency room staff and EMTs, cops said.

Loyce is accused of slashing three men — 26, 28 and 51 — on their hands during the violent frenzy, which only ended when he was zapped with a stun gun, police said.

Devonte Loyce, 19, attacked security guards, nurses and other workers during the pre-dawn rampage, cops said.Citizen APP via Fox News

He also punched a 33-year-old man in the face, bit a 57-year-old man on the right forearm and shoved a 21-year-old woman into a door, authorities said.

A responding NYPD cop needed to deploy a Taser to subdue Loyce and end the rampage, cops said. 

Loyce — whose address is listed as a men’s shelter in Park Slope — was charged with assault, criminal possession of a weapon, resisting arrest and menacing, authorities said.

All of the injured workers were listed in stable condition, cops said.

An officer needed to use a Taser to subdue Loyce, cops said.Kyle Mazza/NurPhoto/Shutterstock

Loyce was just arrested Thursday morning for allegedly snatching a woman’s purse — holding $500 — inside a deli on Fourth Avenue near 86th Street in Bay Ridge, police said. 

The woman ran after the thief, managed to grab her bag back, called the cops and pointed him out to responding officers, authorities and sources said. 

Loyce was arrested and charged with fourth-degree grand larceny, petit larceny and fifth-degree criminal possession of stolen property, according to a criminal complaint.

All of the injured hospital workers were listed in stable condition.Kyle Mazza/NurPhoto/Shutterstock

He was released on his own recognizance during his Brooklyn Criminal Court arraignment several hours later, according to a DA’s Office spokesman.

The Brooklyn theft was not a bail-eligible offense, and Loyce does not have any other prior arrests, the rep said.

Loyce’s violent tear at the Staten Island hospital came as The Post revealed that another man — Edward Johnson, 57 — has repeatedly assaulted female hospital workers in the Bronx.

Loyce was just arrested in Bay Ridge on Thursday for grabbing a woman’s purse — which she was able to retrieve before pointing him out to cops, authorities said.Kyle Mazza/NurPhoto/Shutterstock

Johnson — an illegal immigrant believed to be from the Caribbean who was last arrested in January — violated the terms of his supervised release and is on the run, according to authorities.

One of his repeated victims is Colleen Leahy, an emergency room doctor at St. Barnabas Hospital.

“It’s infuriating that he keeps doing this to health care workers — especially women — and then is let go,” Leahy told The Post Sunday. “They had him in custody multiple times, so why is he being let go to attack other people, other health care workers?”

https://nypost.com/2024/03/04/us-news/teen-bites-slashes-nyc-hospital-workers-in-unhinged-rampage-days-after-he-was-cut-loose-from-jail-cops/

Repeat crime up in New York because of justice ‘reforms’

 Remember back when politicians were touting the success of bail reform? Remember the meaningless and deceptive numbers they threw around?

NYC Comptroller Brad Lander claimed in a report that only 1% of people released on bail under bail reform are rearrested for a violent felony while their case is pending.

State Senate Majority Leader Andrea Stewart-Cousins said the number was 2%.

Remember how the news media and progressive politicians repeated those numbers and claimed that bail reform was a success and had no impact on crime, even as crime rose 30-40% after bail reform took effect?

Well, a new study of bail reform outside New York City — suburbs and upstate — prepared by John Jay College of Criminal Justice’s Data Collaborative for Justice shows that 66% of the people released under bail reform who had a recent prior arrest were re-arrested within two years of their release.

The DCJ study also showed that 67% of defendants who had a recent prior violent felony arrest in the past year who were released under bail reform were re-arrested within two years of their arraignment.

Almost half — 49% — were rearrested for a felony. 

The fact that a study shows that people who have committed crimes tend to continue to commit more crimes is not really surprising.

My analysis of bail reform published by the Manhattan Institute in August of 2022 showed NYC re-arrest rates of close to 70% for people with prior records charged with larceny, burglary, robbery, and criminal contempt while their case was pending.

But DCJ is no conservative think tank. On the contrary, they have been vocal supporters of, and cheerleaders for, New York’s disastrous bail reform laws from the beginning.

This particular DCJ study was supported by the Arnold Ventures Philanthropic Trust, a pro bail reform philanthropic group.

That’s why the numbers that DCJ calculated are so interesting. DCJ won’t say it outright, but their numbers show that bail reform has been a failure — as if the rising crime rate after bail reform was not enough proof.

In fact, the DCJ tries to suggest bail reform is a success because, “Across all of New York State, bail reform tended to reduce recidivism for people facing less serious charges and with limited or no recent criminal history.”

But is that really who we should be worried about? Opponents of no-bail are worried about repeat, chronic offenders rather than one-time criminals.

And, in fact, DCJ study found that bail reform “tended to increase recidivism for people facing more serious charges” (violent crimes) “and with recent criminal histories.” 

In other words, bad people and repeat offenders committed crimes at a higher rate under bail reform than a similar group who had bail set or were remanded under the old bail law.

A previous DCJ study on NYC also found that the 2020 amendments to the original bail reform law, which slightly toughened the bail laws to allow judges to set bail on certain repeat offenders, actually reduced recidivism.

And yet even these sky-high re-arrest rates actually undercount the damage these released defendants cause, since they only count the number of defendants who get re-arrested, not the number of times they get re-arrested.  Nor does every crime result in an arrest.

Arrests outside NYC decreased from 184,000 in 2019 to 154,000 in 2022, even as crimes increased. In fact, while there were 17,000 more crimes in 2022 than in 2019, there were 30,000 fewer arrests.

More people are getting away with crime without being arrested, lowering re-arrest rates..

Recidivism is the problem. Last year the NYPD released a study that showed that just 327 people were responsible for 30% of all shoplifting arrests in NYC in 2022.

They were arrested an average of 20 times each that year

There is no telling how many times they got away with shoplifting and didn’t get arrested.

But can you imagine the decline in shoplifting that would have occurred had just those 327 individuals been held in jail after say, their FIFTH shoplifting arrest that year? 

Allowing judges to consider the defendant’s danger to public safety and risk of recidivism when setting bail (as the overwhelming majority of states and the federal government do) would go a long way to protecting the public.

This is not rocket science. Anyone involved in the criminal justice system could tell you with a pretty high degree of accuracy that people with long criminal records, especially recent criminal records, tend to continue their criminal activity.

  • 66% of the people arrested in the first six months of 2023 in New York State for a felony had a prior conviction or a pending case when they were arrested.
  • 20% had a pending non-violent felony
  • 10% had a pending violent felony.

That is why bail reform was so harmful. In addition to releasing 2,000 career criminals from NYC jails and thousands more from suburban and upstate jails, bail reform prevented judges from setting bail on many of these same individuals when they got arrested and so they were set free to re-offend. 

The problem with this study is that the authors are desperately trying to find ways to declare bail reform a success. They claim victory because “overall” recidivism is down from a control group before the law passed.

But that’s a poor comparison, because so many more criminals are being set free that even if the “rate” of recidivism is going up by a small percentage, the overall number of crimes increases by a lot.

And again, comparing the recidivism of people arrested for their first crime misrepresents what the major opposition to no-bail laws are: In short, that judges don’t have the discretion to take criminal history into account.

The study’s authors at one point concede that statistics “indicate that the mandatory release of people with recent justice involvement, even if relatively minor, can be detrimental to recidivism.”

That is the lesson that New York politicians refuse to take to heart.

Jim Quinn was executive district attorney in the Queens DA’s Office, where he served for 42 years.

https://nypost.com/2024/03/03/opinion/bail-fail-study-shows-that-repeat-crime-increased-in-new-york-because-of-justice-reforms/

Baxter considers selling kidney care unit to private equity

 

  • Baxter International is considering selling its kidney care business instead of spinning it out.

  • The company disclosed in a U.S. Securities and Exchange Commission filing on Monday that it had been in recent discussions with private equity investors about a potential sale of the segment.

  • Whether through a spinoff or sale, Baxter plans to separate its kidney care segment in the second half of 2024.

Baxter first announced plans last year to spin out its renal care and acute therapies businesses into a separate, publicly traded company. The changes were intended to simplify Baxter’s structure and narrow its focus to hospital solutions and connected care. 

The new company, called Vantive, would include dialysis and organ support therapies. Last year, the unit brought in $4.45 billion in sales, about 30% of Baxter’s total revenue.

Baxter has previously said the spinoff would occur by July. The company said it has not made a final decision on the separation structure, and it continues to make progress toward the spinoff that was first proposed.

Last year, Baxter sold its biopharma solutions business for $4.25 billion to private equity firms Warburg Pincus and Advent International.

https://finance.yahoo.com/m/6256484f-11c9-3fcf-8467-0d1c83dc23b7/baxter-considers-selling.html

Novartis new data on safety and efficacy of Zolgensma in older and heavier children with SMA

 

  • The SMART study supplements a growing body of evidence on the use of Zolgensma in a patient population older and heavier (1.5 – 9.1 years of age) than the children treated in previous clinical studies 1-6

  • Nearly all patients treated maintained or improved motor milestones after 52 weeks, with most switching to the one-time gene therapy from another chronically administered disease-modifying therapy 1-6

  • The SMART study is the first open-label clinical study of Zolgensma to include previously treated patients

Avidity Dives After Reversal Of Disease Progression In Neuromuscular Disease

 Top-notch biotech stock Avidity Biosciences (RNA) collapsed Monday despite unveiling "positive" midstage test results for its muscular dystrophy treatment.

Avidity tested its drug in patients with myotonic dystrophy type 1, a form of muscular dystrophy in which patients can't relax their muscles at will. Long-term data suggest Avidity's treatment, dubbed delpacibart etedesiran, helped reverse disease progression, Avidity said in a news release. Patients showed improvements across multiple measures of disease severity.

"We think the most important take-away from this readout is that Avidity has reached regulatory agreement on the Phase 3 (study called) Harbor design and will be able to initiate earlier than expected," Leerink Partners analyst Joseph Schwartz in a report.

But Avidity stock tumbled more than 12% to 17.58 in morning trades on today's stock market. This was the steepest dive of any biotech stock trading above 10, according to MarketSurge.com. Avidity stock bottomed out at 4.83 in October and, as of Friday's close, had reversed that for a 316% gain.

https://www.investors.com/news/technology/biotech-stock-avidity-stock-muscular-dystrophy-treatment/

Cellectar Biosciences Is An 'Attractive Acquisition Target': Roth

 Cellectar Biosciences Inc 

+ Free Alerts
 announced that iopofosine I 131 combined with external beam radiation therapy (EBRT) was safe and tolerated in a SPORE Grant-supported investigator-initiated Phase 1 trial.

The twelve patients treated for locoregionally recurrent head and neck squamous cell carcinoma previously received chemoradiation alone (42%), surgery (58%) or surgery combined with radiation or chemoradiation (92%).

Complete remission was achieved in 64% of patients, with an ORR of 73% (n=11). 

Before treatment with iopofosine I 131, six patients had multiple recurrence, and one had metastatic disease.

Additionally, the study demonstrated the durability of tumor control with an overall survival of 67% and progression-free survival of 42% at 12 months.

Overall, eleven patients (92%) experienced a treatment-related adverse event. 

The most common treatment-related adverse events of any grade were thrombocytopenia (92%), lymphopenia (75%), neutropenia (75%), and anemia (92%). 

Observed adverse events were consistent with the known toxicity profile of iopofosine I 131, with cytopenias being the most common with all patients recovering.

Roth Capital highlights the positive outcomes of iopofosine I 131 across various disease contexts, positioning Cellectar Biosciences as an appealing acquisition target. 

“We note that iopofosine I 131 is showing benefit in several disease settings (e.g., WM, MM, DLBCL, HNSCC), which, in our view, only makes CLRB a more attractive acquisition target, despite it making a full effort to commercialize the drug itself,” Roth writes.

The analyst put a price target of $20.

Despite the company’s dedicated efforts to market the drug, its systemic administration suggests potential benefits in addressing the primary tumor and treating micrometastatic disease beyond conventional radiation boundaries.

In January, Cellectar Biosciences announced data from its CLOVER WaM pivotal study, evaluating iopofosine I 131, a targeted radiotherapy candidate for the treatment of relapsed/refractory Waldenstrom’s macroglobulinemia (WM) patients that have received at least two prior lines of therapy

The CLOVER WaM study met its primary endpoint with a major response rate (MRR) of 61%. 

The overall response rate (ORR) in evaluable patients was 75.6%, and 100% experienced disease control. 

https://www.benzinga.com/analyst-ratings/analyst-color/24/03/37465044/cellectar-biosciences-is-an-attractive-acquisition-target-according-to-this-analyst

Is Stretching Now Underrated? Accumulating Research Says Yes

 For many, stretching is the fitness equivalent of awkward small talk. It's the opening act, the thing you tolerate because you know it will be over soon. 

Others have challenged the practice, suggesting that stretching isn't necessary at all. Some research has found that a preworkout stretch may even be disadvantageous, weakening muscles and hindering performance.

To put it plainly, no one seems terribly enthusiastic about touching their toes. 

That's why a 2020 study on exercise and mortality was such a head-scratcher. The study found that stretching was uniquely associated with a lower risk for all-cause mortality among American adults. That's after controlling for participation in other types of exercise. 

The finding seemed like a fluke, until a 2023 study found essentially the same thing. 

Among Korean adults, those who did flexibility exercise at least five times a week had a 20% lower risk of dying during the follow-up period than those who didn't stretch at all. That was slightly better than the risk reduction associated with high volumes of aerobic exercise and resistance training. 

How can that be ? It turns out, stretching is linked to several health benefits that you might not expect. 

The Surprising Benefits of Stretching

When we talk about stretching, we usually mean static stretching — getting into and holding a position that challenges a muscle, with the goal of improving range of motion around a joint. 

It doesn't need to be a big challenge. "Research shows you can get increases in flexibility by stretching to the initial point of discomfort," said David Behm, PhD, an exercise scientist at Memorial University of Newfoundland in Canada who's published dozens of studies on stretching over the past quarter-century. 

That brings us to the first benefit. 

Stretching Benefit #1: More Strength

At first glance, flexibility training and strength training have little in common. You lengthen muscles in the former and contract them in the latter. 

But in both cases, Behm said, you're applying tension to muscles and connective tissues. Tension activates proteins called integrins, which send and receive signals across cellular membranes. Those signals are the start of a cascade that leads to protein synthesis. That's how muscles get bigger and stronger when you lift weights. 

That mechanism could explain the small gains in muscle strength and size associated with static stretching, Behm said. 

But can you really stretch your way to muscle growth? Theoretically, yes. But strength training is far more time-efficient, Behm says. Studies showing increases in muscle mass have typically stretched a single muscle (usually the calves, using a specialized device) for > 30 min/session, 6 d/wk for 6 weeks. And that's for just one leg.

Still, stretching may be more accessible for some patients — research suggested that older and more sedentary people are most likely to benefit from stretching-induced gains in strength. 

Stretching Benefit #2: Reduced Arterial Stiffness

"Most people don't think about the cardiovascular benefits of stretching," Behm said. There are some big ones. 

If your body doesn't move well, it's not unreasonable to assume your blood doesn't flow well. That is indeed the case: Poor flexibility is associated with arterial stiffness

Stretching is associated not only with improved arterial function but also with reductions in resting heart rate and blood pressure and increased vasodilation.

Mobility improvements may have an indirect benefit on cardiovascular health as well. 

"Studies show runners are more economical when they're more flexible," Behm said. If your movement is more efficient, you'll probably do more of it. Doing more, in turn, would lead to improved fitness. 

Stretching Benefit #3: Improved Performance

Research is equivocal on whether stretching improves athletic performance, said Joe Yoon, a sports massage therapist in Orlando, Florida, and author of Better Stretching

"But I've always taken the approach that if you can improve your range of motion and get into positions" required for your sport, you'll probably perform better, with less risk for injury, Yoon said. 

It's worth noting that some research over the past 30 years has linked pre-exercise static stretching with a loss of strength, power, and/or speed. 

But consider this: In a 2016 review, Behm and his coauthors showed that performance reductions were most likely to occur in two situations

  • When participants did extremely long stretches (duration, ≥ 60 sec per muscle).
  • When researchers tested the participants' strength, power, or speed immediately after they stretched.

Avoiding those problems is easy, Behm said: Stretch each muscle for < 60 sec, and combine static stretches with more active warm-up exercises. 

"Stretching can impair your performance but only if you do it wrong," he said.

Stretching Benefit #4: Fewer Injuries

When you stretch, the point where you feel tension is where the muscle is most vulnerable. "That's where injuries usually happen," Behm said. 

More flexibility in those areas allows your muscles to safely generate force at longer lengths. For an athlete, that means fewer injuries when they're doing explosive movements or changing direction. 

For nonathletes, flexibility reduces injuries by improving balance. Better balance reduces the risk of falling and helps mitigate the damage if you do take a tumble. 

Help Your Patients Get the Benefits of Stretching

Stretching, like training for endurance or strength, can be as complex as you want to make it. But Yoon advocates a simpler approach. 

"You see this flashy stuff online," he said. "But if you see those trainers in real life or you book a session with them, they go right back to the basics." 

Ideally, Yoon said, a flexibility routine will work the entire body. But if that's too big a stretch for your patient, he recommends starting with one or two stretches for the most problematic area. 

For example, for a stiff back, try doing the puppy pose at least once a day, although twice is better. Hold the position for 30 seconds to 2 minutes, said Yoon. Even if you combine it with a dynamic movement like the cat-cow, the two exercises would take just a few minutes a day. 

"There's this misconception that you have to do a lot of it to be successful," Yoon said. 

Consistency is far more important than volume. Yoon recommends "a little bit every day — the minimum viable dose." 

As a bonus, stretching an area like your upper back will probably improve your shoulder mobility, Yoon said. Same with your lower body: Stretches for your hips, over time, should also benefit your knees and lower back. 

And thanks to a phenomenon called nonlocal flexibility transfer, lower-body stretches should improve upper-body flexibility, at least temporarily. Shoulder stretches can also have an immediate effect on hip mobility. 

"It's all connected," Yoon said, which brings us back to where we started. 

If stretching can indeed reduce mortality risk, it's probably because of interconnected pathways, rather than any single mechanism. 

Most obviously, stretching improves flexibility, which makes movement easier, improves balance, and reduces the risk for falls and other types of injuries. It can also lead to small improvements in strength. Less obviously, stretching improves several aspects of cardiovascular function, including circulation. 

"There seems to be a global effect in everything we do," Behm said. "Whether you're stretching or weight training, the message is sent throughout your body.

https://www.medscape.com/viewarticle/stretching-now-underrated-accumulating-research-says-yes-2024a10003s2