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Wednesday, June 25, 2025

Hey Dems: Unseat Mamdani And You’ll Win The 2028 National Election

 by QTR's Fringe Finance

I think it was Mark Twain who said “every massive communist nightmare of a problem with a chance to destroy the most iconic city in American history is an opportunity in disguise”. Maybe it was Milton Friedman. Or Kim Kardashian.

I can’t remember.

But the point is that Zohran Mamdani’s win in the New York City Mayoral Democratic primary tonight could actually turn out to be a national moment of truth for the Democratic Party.

After a bruising 2024 presidential defeat, one in which Democrats were widely criticized for alienating moderates and independents with a platform that veered too far left, the party now finds itself at a crossroads. Again.

Among many, well-known (former) Democrats like Ana Kasparian, Bill Ackman, Joy Reid, Elon Musk and former Rep. Jared Golden have distanced themselves—if not removed themselves—from the party altogether. More will soon follow.

This New York City mayoral election is no longer a local issue—it’s a symbolic referendum on whether Democrats have learned anything from their recent loss, or if they’re content to continue losing the middle in pursuit of ideological purity.

2024 should have been winnable for Democrats. The Republican Party fielded a polarizing candidate, the economy was relatively stable, and yet voters across the country turned away because they feared what the Democrats were becoming.

Centrist voters who once leaned blue looked at the messaging, the priorities, the excesses and the socialism, activism and radical policy stances and simply said “enough”.

In the nation’s most important city, Democrats are voting for a platform that feels like it was written during a fireside drum circle in the quad of Evergreen University.

Free housing. Free transit. Free groceries—courtesy of government-run stores. A policing strategy that replaces cops with counselors and bureaucrats with badges. Tax hikes that seem designed not to generate revenue, but to punish — and will assuredly lead to a massive capital outflow from New York. It’s not policy, it’s bullshit performance art that has no chance of being effective in one of the world’s most important geographic locations. And it is everything that turned off centrist Democrat voters in 2024.

So here’s the opportunity: Democrats can make a statement—not just to New York, but to the country—that they are still the party of rational governance and common sense — and that they can self-correct. That they are capable of breaking with their worst parts when it matters.

And it matters now.

This means one thing for the Democratic party: backing a centrist, independent candidate in November who can beat Mamdani in the general. Not a protest candidate. Not a placeholder. A real, serious contender who speaks to the exhausted majority that is desperate for competence over chaos.

Yes, it would mean bypassing your own party’s nominee. Yes, it would mean a messy, unscripted break with tradition. But it would also be a powerful signal to the rest of the country: we heard you. We understand that winning elections in a diverse, divided nation means appealing to a broad coalition. Not just activists and donors, but homeowners, working-class voters, small business owners, families, and independents.

Democrats have a chance—right now—to show they’ve learned from their mistakes. That they’re not doubling down on the same playbook that cost them the White House, House seats, and voter trust.

Let’s be clear: the only viable path forward is an independent candidacy with full-throated support from party leaders, major donors, national figures, and the rank-and-file who quietly know this has gone too far.

And the media must stop treating this like some heartwarming tale of a plucky outsider shaking up the system. This isn’t a feel-good story. It’s the slow-motion capture of a governing disaster in the making. If Democrats let it happen unchallenged, they’ll be complicit—not just in Mamdani’s mayoralty, but in further defining the national brand as unserious, unanchored, and unelectable.

Because if Mamdani wins, it won’t just be a local experiment gone wrong. It’ll be seen as confirmation that the Democratic Party is unable—or unwilling—to police its own excesses.

And that message won’t stop at the Hudson. It’ll ripple across every swing district, every suburban race, every national conversation where voters are quietly asking: who is looking out for the middle anymore?

This is Democrats’ chance to answer. And I can’t believe I’m saying this, but I hope they don’t waste it.

https://www.zerohedge.com/markets/hey-dems-unseat-mamdani-and-youll-win-2028-national-election

NATO Leaders Agree To 5% Hike In Defense Spending As Rutte Warns 'No Opt-Outs Or Side Deals'

 As expected, NATO members have agreed to new commitment to significantly boost defense spending, aiming to raise military budgets to 5% of GDP over the next decade—more than double the current 2% benchmark—at the ongoing major annual summit being held in The Hague. NATO's 32 leaders proclaimed Wednesday: “Allies commit to invest 5% of GDP annually on core defense requirements as well as defense-and security-related spending by 2035 to ensure our individual and collective obligations.”

The Trump-backed decision is being finalized in Netherlands this week, with NATO Secretary General Mark Rutte having hailed the proposal as a "quantum leap' during a press briefing. Trump declared Tuesday that we're with NATO "all the way". And on Wednesday he's expected to give a big address, as all eyes are focused on the Iran bombing and what's next.

The only real surprise out of the summit: Zelensky dons a suit.

Bloomberg notes, also as fully expected and long ago previewed, that the spending target includes 3.5% via core defense and 1.5% in related investment covering infrastructure and cybersecurity.

Rutte and officials gathered in the Netherlands have stressed that all member states must participate, highlighting that Spain’s hesitation over the steep cost—nearly $90 billion annually—will not exempt it from the pledge. "NATO doesn’t allow for opt-outs or side deals," he has firmly stated.

The increased funding is intended to dramatically scale up NATO’s military production, including building thousands of tanks and multiplying air defense systems by five, at a moment the alliance is staring down Russia amid the Ukraine war, where Moscow forces are establishing a huge buffer zone in the north and east, and actually increasing territory beyond Donetsk's western border.

WikiLeaks meanwhile says the arms companies will continue to be the only real winners...

Rutte has of course identified Russia as NATO’s "most significant and direct threat" and reiterated full support for Ukraine, despite Washington having named China has America's 'top pacing threat' and long-term main miliary and economic rival.

Of course, the alliance has already funneled hundreds of billions of dollars into a conflict with Russia that has resulted in hundreds of thousands of lives on both sides, and all the while Ukraine losing about 20% of its territory.

NATO leaders as of Wednesday have vowed to keep pursuing Ukraine’s path to membership, with Rutte emphasizing that the question of accession was never ruled out, especially not before the war. "There is an irreversible path for Ukraine to join NATO—and that remains true today, and will still be true after this summit," he has said.

All of these pledges are new commitments were no surprise after Trump long pushed for drastically ramped-up spending, but perhaps the only surprise is that Ukraine's President Zelensky finally swapped out his green uniform for a black suit (of sorts)...

PA Wire/Telegraph

Dressed to impress? Zelensky must want into NATO very, very badly.

https://www.zerohedge.com/geopolitical/nato-leaders-agree-5-hike-defense-spending-rutte-warns-no-opt-outs-or-side-deals

Glucotrack, OneTwo Analytics Final Results of 1st Human Study for Continuous Blood Glucose Monitor at ADA



Glucotrack (NASDAQ:GCTK) has announced positive final results from its first-in-human clinical study for its innovative Continuous Blood Glucose Monitor (CBGM) at the American Diabetes Association's 85th Scientific Sessions. The study demonstrated excellent accuracy with a MARD of 7.7% across 122 matched pairs and a 99% data capture rate, with no serious adverse events.

The implantable CBGM technology measures glucose directly from blood rather than interstitial fluid, eliminating typical lag time associated with traditional monitors. The study, conducted in Brazil from December 2024 to January 2025, included ten Type 1 or Type 2 diabetes patients. Analysis showed 92% of measurements in the green zone of the Diabetes Technology Society Error Grid, indicating high clinical accuracy.

The company plans to initiate a long-term early feasibility study in Q3 2025. The CBGM system is designed for a three-year sensor life with no on-body wearable component and minimal calibration requirements.

FDA clears Plus Therapeutics’ pediatric brain cancer treatment trial

 The U.S. Food and Drug Administration has cleared Plus Therapeutics’ (NASDAQ:PSTV) Investigational New Drug application for REYOBIQ to treat pediatric patients with high-grade glioma and ependymoma, the company announced Wednesday.

The Phase 1/2a clinical trial, named ReSPECT-PBC, will be funded by a $3.0 million grant from the U.S. Department of Defense. The study will enroll children aged 6 to 21 years, with consideration for patients up to 25 years on a case-by-case basis. 

The trial will follow a two-part design. Phase 1a/b will enroll approximately 24 patients to establish the maximum tolerated dose, while Phase 2a will include about 32 patients to assess efficacy.

REYOBIQ (Rhenium Re186 Obisbemeda) is designed to deliver beta radiation directly to brain tumors while minimizing damage to surrounding healthy tissue. The treatment uses convection enhanced delivery to bypass the blood-brain barrier.

"Surgery and external beam radiation have been the mainstays of treatment for pediatric high-grade glioma and, sadly, outcomes have not improved for many decades," said Dr. Ashley S. Plant, Principal Investigator for the trial and attending physician at Ann & Robert H. Lurie Children’s Hospital of Chicago.

Pediatric high-grade gliomas, including ependymoma, are rare but aggressive brain tumors with limited treatment options. Standard treatments often fail to prevent recurrence, with five-year survival rates as low as 22% for high-grade glioma.

The pediatric trial builds on Plus Therapeutics’ adult recurrent glioblastoma trial (ReSPECT-GBM), which according to a press release statement showed favorable safety and clinical response.

https://www.investing.com/news/company-news/fda-clears-plus-therapeutics-pediatric-brain-cancer-treatment-trial-93CH-4110233

Sanofi's Riliprubart Secures U.S. Orphan Drug Status For Solid Organ Transplant Rejection

 The U.S. Food and Drug Administration has granted orphan drug designation to riliprubart for the investigational treatment of antibody-mediated rejection (AMR) in solid organ transplantation, Sanofi Winthrop Industrie said in a statement.

Riliprubart has also been designated an orphan drug for its investigational use in treating chronic inflammatory demyelinating polyneuropathy in the US and European Union.

Riliprubart is currently being explored in multiple clinical studies across different indications in transplant and neurology. A phase 2 clinical study is currently ongoing, exploring its potential in kidney transplant recipients.

https://www.nasdaq.com/articles/sanofis-riliprubart-secures-us-orphan-drug-status-solid-organ-transplant-rejection

US exchanges, SEC in talks to ease public company regulations

 U.S. exchange operators are in talks with the Securities and Exchanges Commission on easing regulatory burdens for public companies, as they seek to encourage more richly valued startups to list, according to four people familiar with the matter.

These deliberations, the details of which are reported here for the first time, involve the SEC, Nasdaq and the New York Stock Exchange. The reforms under discussion range from reducing the quantum of disclosures and the costs of going public to making it harder for minority investors to agitate, the sources said, requesting anonymity as they were not authorized to speak publicly.

The talks, which the sources said have been ongoing for several months, come amid a renewed push to ease regulations under President Donald Trump, whose administration has said it wants to do so to spur economic growth.

Taken together, some market experts said these discussions could mark the most significant push to introduce regulatory reform for companies since the Jumpstart Our Business Startups Act was signed into law by former President Barack Obama in 2012, and build on efforts seen during Trump's first term.

"The numbers are very clear that companies are staying private longer," Nasdaq President Nelson Griggs told Reuters. Griggs said the exchange operator has discussed making public markets more attractive with regulators in Washington but did not specify which agencies.

"We need to make the public markets attractive because that is really how you democratize access to these companies. So it's a big focus of ours," Griggs said. Nasdaq has publicly made the case for easing burdens by using remedies such as the modernization of the process for proxy filings.

In a statement to Reuters, Jaime Klima, general counsel of NYSE Group, said the exchange will "continue to advocate for our listed companies with regulators and policymakers.”

"We strongly believe that effective and efficient regulation is key to maintaining the attractiveness of our markets," Klima said, without specifying any specific discussions ongoing.

The SEC, led by new chairman Paul Atkins, said it is looking to ease rules that can impede capital formation.

"The SEC is considering addressing regulatory burdens that undermine capital formation, including (ensuring) that initial public offerings are again something companies are eager to do," a spokesperson for the agency said.

https://finance.yahoo.com/news/exclusive-us-exchanges-sec-talks-101858903.html

Walmart Looks to Speed Up Delivery by Opening ‘Dark Stores’ Closed to the Public

 Walmart Inc. is testing dark stores, which resemble retail stores but are closed to the public, as a way to speed up deliveries. 

The company has opened one of these smaller warehouses in Dallas and plans to add another in Bentonville, Arkansas, where Walmart is based, according to people with knowledge of the matter who weren’t authorized to speak publicly. Walmart is exploring adding more locations, the people said.

Faster delivery is a key priority area for Walmart, as shoppers are increasingly paying more to get their purchases faster. The dark stores aim to help the company cover a wider delivery radius and improve speed, as it seeks to better compete with Amazon.com Inc. and other digital giants. 

A Walmart spokesman said the company regularly tests new tools, features and capabilities with the goal of delivering a fast, smooth customer experience. 

The new dark stores will carry some of the most popular items that shoppers buy, amplifying the reach of existing stores and bigger warehouses that fulfill orders. Walmart operated a handful of similar warehouses during the mid-2010s through the pandemic before closing them. 

In recent years, the company has focused on expanding its digital operations by offering new services such as pharmacy delivery. Walmart has also broadened its marketplace for third-party sellers, adding more brands, expanding price points and entering new categories.  

Other retailers have also set their sights on fast delivery, which typically come with extra fees that help offset costs associated with online orders. 

Walmart expects its online business to hit profitability this year after investing billions of dollars to better compete with Amazon. To trim costs, the company has batched more orders together and is automating the retrieval and packaging of items in warehouses

https://www.msn.com/en-us/money/companies/walmart-looks-to-speed-up-delivery-by-opening-dark-stores-closed-to-the-public/ar-AA1Hluq8