Search This Blog

Saturday, September 6, 2025

OPEC+ Agrees in Principle to Increase Production in October

 


OPEC+ has agreed in principle to increase production again next month, according to delegates, as the group doubles down on its policy shift to pursue market share instead of defending prices.

Key alliance members said they expect to approve adding about 137,000 barrels during a video call on Sunday, as the group led by Saudi Arabia and Russia begins unwinding the next layer of halted supplies, having just completed the surprise fast-tracking of a previous tranche. An October increase will start the return of 1.66 million barrels a day of cuts that were scheduled to remain in place until the end of 2026. Some of the delegates added that discussions are ongoing.

https://www.bloomberg.com/news/articles/2025-09-06/opec-agrees-in-principle-to-increase-production-in-october

Eyebrow-Raising Details Emerge From FBI Raid On John Bolton's Home

 Federal Bureau of Investigation agents seized three computers, two iPhones, and multiple documents from the Bethesda, Maryland, home of former Trump national security advisor John Bolton on August 22, according to a report released Friday. The raid is part of an ongoing investigation into whether the infamous war hawk mishandled classified documents, including allegations he emailed sensitive files to family members via a private server.

The New York Post reported new details about the raid:

In addition to the high-tech hardware, agents confiscated two USB drives, a hard drive, four boxes of “printed daily activities,” “typed documents in folders labeled ‘Trump I – IV'” and a white binder labeled “statements and reflections to allied strikes,” according to an inventory made public Thursday.

The warrant also revealed that Bolton is being looked at for allegedly violating two sections of the Espionage Act of 1917 forbidding unauthorized possession or removal of national defense information, and another law preventing hoarding of classified files.

The investigation, which intensified under the Biden administration, also centers on personal emails allegedly obtained by a foreign government’s spy agency, according to people familiar with the matter cited by the New York Times. The emails reportedly contained classified information Bolton sent to close associates while gathering material for his 2020 memoir, “The Room Where It Happened.” The FBI’s search of Bolton’s home aimed to determine if he possessed materials that could verify the authenticity of the compromised emails.

During the Trump administration, the Justice Department initiated a criminal probe into whether Bolton mishandled classified material in his book. The administration also sued to delay the memoir’s publication. Although the book was released, a federal judge, Royce Lamberth, concluded that “Defendant Bolton likely jeopardized national security by disclosing classified information in violation of his nondisclosure agreement obligations.” However, Judge Lamberth declined to block distribution, noting, “the horse is already out of the barn,” as excerpts had been published and 200,000 copies had shipped.

The Times sources indicated that the information allegedly obtained by the foreign spy agency was not included in Bolton’s book. The investigation into Bolton reportedly stalled under Biden for reasons that remain unclear.

An FBI agent, speaking to the Post, criticized the pause, telling the newspaper, “The [Biden administration] had probable cause to know that he had taken material that was detrimental to the national security of the United States, and they made no effort to retrieve it.”

The agent added, “That was a friendly administration to [Bolton]. They kept bashing [Trump] the entire time for ‘weaponizing law enforcement,’ and they - by politically stopping a righteous investigation - are the ones who weaponized law enforcement.

Bolton, who has not been charged or arrested, denies any wrongdoing. If convicted on all potential charges, he could face up to 25 years in prison.

https://www.zerohedge.com/political/eyebrow-raising-details-emerge-fbi-raid-john-boltons-home

It’s Official Biden Made Poor Poorer and Trump Made Everyone Richer

 Our new study, based on our advance estimates of Census Bureau data on income shows big money gains for all income groups under Trump, and almost no gains for the poor and middle class under Biden. You can get a summary of the findings in today’s major feature piece in the New York Post.

The findings resoundingly contradict the Left’s frequent claims that Trump’s tax and budget policies primarily favored the rich. In truth, the purchasing power of Americans in the bottom quarter of household income rose by 10% during his first White House term. The poor lost income under Biden policies because of the high inflation. Even though his priority was to reduce income inequality, the gap between rich and poor grew wider from 2020-24.

Those income gains under Trump 1.0 likely would have been much higher if COVID lockdowns hadn’t choked off large sectors of the economy in 2020. Also, these numbers in the chart are pre-tax, so when we take into account the Trump 2017 tax cuts, the average family gained about $8,000 in after-tax incomes.

https://committeetounleashprosperity.com/hotlines/its-official-biden-made-poor-poorer-and-trump-made-everyone-richer/

FDA Investigating Reports of Child Deaths After COVID Vaccination, Makary Says

 The FDA is carrying out an "intensive investigation" into whether COVID-19 vaccines have caused deaths in children, according to Commissioner Marty Makary, MD, MPH.

"We do know at the FDA, because we've been looking into the [Vaccine Adverse Event Reporting System] database self-reports, that there had been children who have died from the COVID vaccine," Makary said in an interview with CNNopens in a new tab or window.

When asked how many deaths were caused by the vaccine, Makary said the FDA would release a report in the coming weeks. The FDA is talking with family members, reviewing autopsy reports, and having physicians do the review, he explained. "We think the public deserves to have that information."

He said that children, particularly boys, are at increased risk of myocarditis after COVID vaccination, asserting that the incidence rate could be one in 2,600 for males between the ages of 17 and 24 years.

The CDC has posted safety dataopens in a new tab or window on the COVID vaccine and myocarditis. Noting that "the evidence suggests that, although rare, these events are linked to certain types of COVID-19 vaccinations," the CDC added that "surveys of patients diagnosed with myocarditis who developed symptoms at least three months prior to answering the survey showed most patients (80%) were considered by their cardiologist or other healthcare provider to have either fully or probably fully recovered."

Makary said in the interview that when asked for data about the potential myocarditis link, the CDC blocked such requests and made excuses. "It was those individuals who resigned from the CDC, that were in leadership, that gave us the hard time about getting the data," he added.

"We want to get good data so people can make ... a risk-benefit analysis for their age group," he said. "We shouldn't be using dogma to say everybody should get [a COVID vaccine], and regardless of your circumstance."

Makary's remarks come in the wake of the FDA's tightened restrictionsopens in a new tab or window on who should get COVID vaccines, restrictions that could force most vaccinations for children off-label.

The agency approvedopens in a new tab or window updated 2025-2026 COVID vaccines late last month for all adults 65 and older, but only for kids and younger adults with an underlying condition. Previous years' vaccines had been approved for everyone 6 months and up.

The American Academy of Pediatrics (AAP) broke with federal COVID vaccine recommendations, issuing its own recommendationsopens in a new tab or window in August. In a statement, AAP President Susan J. Kressly, MD, called the new proposal to limit the availability of COVID vaccines in children and young adults "deeply troubling."

The "unprecedented action from HHS not only prevents this option for many families, but adds further confusion and stress for parents trying to make the best choices for their children," she said.

In the CNN interview, Makary shot back that the AAP "is the same group that insisted that schools stay shut down" during the COVID-19 pandemic.

https://www.medpagetoday.com/infectiousdisease/covid19vaccine/117340

'Most Docs Say It's Fine to Get Tiny Gifts From Pharma: Survey'

 

  • Industry spends $35 billion annually marketing pharmaceuticals, much of it directly to physicians.
  • In this longitudinal study, a majority of doctors surveyed in 2011 and again in 2024 agreed that marketing interactions threaten trust in medicine.
  • Yet most agreed that physicians receive some useful information from pharmaceutical marketing and that gifts under $50 from industry are acceptable.

Most doctors said it's appropriate to accept gifts valued at under $50 from the pharmaceutical industry, according to one of the many findings from a longitudinal study that surveyed physicians at the start of their careers in 2011 and then again last year.

Yet a majority of the participants agreed at both points that marketing interactions threaten trust in medicine, with the share who strongly agreed with that idea growing from 5.6% in 2011 to 14.5% in 2024 (P=0.004), reported Aaron Kesselheim, MD, JD, MPH, of Brigham and Women's Hospital in Boston, and colleagues.

More than 90% of those surveyed last year said that doctors might prescribe pricier drugs without extra benefits or become unconsciously biased toward a certain product as a result of interactions with pharma reps, according to the findings in JAMA Health Forum

opens in a new tab or window.

"Physicians expressed greater concern about pharmaceutical marketing in some spaces, but then also greater recognition that pharmaceutical representative materials are important resources to learn about drugs," co-author Helen Mooney, MPH, also of Brigham and Women's Hospital, told MedPage Today.

The majority of doctors surveyed said they receive useful information from pharmaceutical marketing, growing from 66.3% in 2011 to 76.9% in 2024 (P=0.005). The pharmaceutical industry spends $35 billion annually on drug marketing, much of it directly to physicians, the authors noted.

"It's an interesting contrast, that these materials are recognized to be useful, but then at the same time there was high agreement that trust that patients and the public can have in physicians can be threatened by these marketing interactions, that bias can come from advertising, as it has been demonstrated in the literature," Mooney added.

Bryan Carmody, MD, of Eastern Virginia Medical School in Norfolk, who was not involved with the study, said that "although the authors played up the differences, what's remarkable is how much stayed the same" and that "the directionality of the sentiment was the same for every item, and many are virtually identical from 2011 to 2024."

In the follow-up survey, a majority of respondents agreed to the following statements:

  • It's appropriate for doctors who receive pharma speaking fees about a given drug to then lecture medical students on that same topic
  • Schools should not permit industry sales reps to have access to preclinical students on campus
  • Most free drug samples are given to needy patients as a result of interactions with pharma reps
  • Forcing doctors to disclose financial relationships with drug companies does not impede useful collaborations that would lead to the development of new drugs

Meanwhile, over 75% said that direct-to-consumer pharma advertising is not useful for patients.

The view that limits on pharmaceutical consulting may hamper drug development was slightly higher in the follow-up survey (28.5% vs 23.1% in 2011, P=0.01).

More respondents in 2024 also thought that medical schools shouldn't allow interactions between pharmaceutical companies and students in training facilities (72.2% vs 59.6% in 2011, P=0.004). And there was also greater agreement that schools should require faculty to disclose their conflicts of interest before lectures (99.7% vs 88.9%, P<0.001).

Mooney said there are opportunities to increase policies about conflict-of-interest disclosures in medical school settings and to limit marketing to students.

Carmody noted that what's less clear is whether the shifts the researchers observed are due to changes in individuals' thinking over time -- perhaps with experience, some physicians see more danger in industry-physician interactions, for example -- or changes in the profession or society at large.

Shifting attitudes "may be attributable to respondents' leaving training and assuming professional roles or may represent secular changes over time," Kesselheim and co-authors suggested.

For the study, randomly selected medical students and residents were surveyed about their thoughts and interactions towards the pharmaceutical industry in 2011. The same group was resurveyed in 2024.

In total, 1,610 medical students (of 3,495) and 739 residents (of 1,815) responded to the 2011 survey. Most of the medical students were not attending a top 20 NIH-funded medical school.

Researchers found contact information for 1,130 of the original cohort, though 229 turned out to be invalid, leaving 901 potential respondents. Of those, 294 responded -- a 33% response rate -- and 291 were matched to their 2011 responses.

Among the latest survey respondents, mean age was 41 years and 49.5% were women. Most (71.8%) identified as white, with 20.6% Asian, 5.5% Black, and 4.8% Hispanic or Latino.

Three-quarters of respondents in 2024 worked in hospitals or clinics (74.2%); 30% were at academic research institutions, 27.2% at medical schools, and 24.4% in private practice. Four out of five spent at least half of their time directly caring for patients.

The study was limited by its 13-year timeline, which affected the response rate and led to an oversampling of academic researchers. The survey's self-reporting nature also risked social desirability bias.

Disclosures

This research was supported in part by Arnold Ventures.

Mooney reported prior equity in Johnson & Johnson, AbbVie, Merck, Organon, and Bristol Myers Squibb. Kesselheim reported serving as an expert witness in cases against Gilead and Johnson & Johnson.

Carmody did not report any disclosures.

CDC: Riddled With Metastatic Woke Cancer

by Francis Merton

Last week the newly-confirmed head of the Centers for Disease Control (CDC), Susan Monarez, was abruptly fired by President Trump, barely a month after receiving her Senate confirmation in July. Although Monarez was new to CDC as of the second Trump term, her career in high-level government positions runs back to through the Biden, Trump I, and Obama administrations.

Upon announcement of Monarez’s firing, the press was immediately filled with reports of “turmoil” at the agency. At least four high-ranking officials resigned in protest (even as Monarez tried to hang on). In addition, large numbers of staffers came forward (anonymously) to complain of the supposedly “anti-science” approach being taken by Trump and his HHS Secretary, RFK, Jr. Here is a piece from ABC News from August 28 with some choice quotes:

  • "How are we supposed to function as an agency if everything has to run through a man who doesn't believe in basic scientific principles?" a CDC staffer told ABC News.

  • “[W]e feel hopeless now," a CDC employee told ABC News. "Hopeless for our own research and work to continue, hopeless for our own personal futures, but most importantly hopeless for the future of America's children and what sort of awful future we are setting them up to inherit -- and for what gain or profit?"

  • Another CDC staffer said, "I'm glad to see the pushback from senior leadership standing up for public health -- I'm also upset and concerned about what this means for the fate of CDC and the health of the people we serve."

And then a large coterie of the staff held a “clap out” to show support for the departing officials. From the ABC News piece:

Supporters held signs that said "Fire RFK," "CDC saves lives," and "Leaders like these don't grow on trees." . . . The three officials received a warm welcome as they slowly made their way through the crowd, accepting hugs, flowers, and pats on the back.

I won’t try to stand up for everything (or even most things) that RFK, Jr. is trying to do. But, do you have the impression that CDC is a useful agency, “following the science” and protecting the public health? If so, you haven’t been paying attention to the news for the past several years (or more). In truth, CDC is a completely politicized and anti-science organization, thoroughly riddled with metastatic woke cancer. We’d all be far better off if it were eliminated entirely and we started over from scratch.

Start with the Covid debacle. Although CDC did not purport to issue mandates for things like lockdowns and masking on its own authority, it planted its flag firmly on the side of the supporters of those ineffective measures, and through guidance and recommendations gave support to the worst of the state governments that set about to treat their citizens like prisoners. Then, on September 1, 2020 (Trump was the President!), CDC issued its famous “eviction moratorium,” purporting to prevent anyone from getting thrown out of an apartment for non-payment of rent as a “public health” measure. The moratorium got extended several times during the Biden presidency, until struck down by the Supreme Court in September 2021 as being beyond the CDC’s authority.

The very public and consequential Covid disaster is undoubtedly the biggest source of the public’s loss of trust in the CDC. But there are many other equally valid reasons to hold the agency in contempt. For decades CDC has been engaged in aggressive bureaucratic expansion into areas having little to nothing to do with public health. Here is a piece from 2022 from Dr. Joel Zinberg, writing in the New York Post, detailing some of the more egregious examples of what he calls CDC “mission creep.” Excerpt:

The CDC’s priorities now include addressing “the public health consequences of the climate crisis,” “reducing racial disparities in public health,” addressing “the social determinants of health, conditions in the places where people live, learn, work, and play” and “increases in injury and violence prevention programs that will help to address the growing crisis of domestic, sexual, and gun violence.”

And now we get to my personal favorite, the October 2021 Report titled “Advancing Health Equity: A Guide to Language, Narrative and Concepts.” This one is pure Biden administration Peak Woke. Although it says on the cover that it is a product of the American Medical Association and the Association of American Medical Colleges, it is very much a joint effort with the CDC. The list of “contributors and reviewers” at the end lists some 14 from CDC (compared to 29 from the AMA and only 7 from the AAMC).

How bad is this thing? A fair summary of “Advancing Health Equity” would be that if you just stumbled across it at random, you would be sure that it is a parody. It is not.

Start with the Preamble. There we find — you guessed it — the “land acknowledgement.” Excerpt:

The American Medical Association’s headquarters is located in the Chicago area on taken ancestral lands of indigenous tribes, such as the Council of the Three Fires, composed of the Ojibwe, Odawa and Potawatomi Nations, as well as the Miami, Ho-Chunk, Menominee, Sac, Fox, Kickapoo and Illinois Nations. . . . We acknowledge their ancestors were forced out by colonization, genocide, disease and war. The AAMC and AMA also acknowledge the extraction of brilliance, energy and life for labor forced upon millions of people of African descent for more than 400 years.

Then there is the substance of the document. According to this AHE Report, the big problem causing health inequity is not deficient medical care, but rather the use of the wrong “narratives.” And the solution is to force the use of the correct narratives. The claim is that great harm has been done by use of the “dominant narratives,” also known as “malignant narratives,” that “undermine public health and the advancement of health equity.” These “dominant” and “malignant” narratives are the ones that contain such evil concepts as “meritocracy,” “individualism,” and “medicine itself”:

Central to this work is a consideration of our language, and the narratives that shape our thinking. As we explore in this guide, dominant narratives (also called malignant narratives), particularly those about “race,” individualism and meritocracy, as well as narratives surrounding medicine itself, limit our understanding of the root causes of health inequities. Dominant narratives create harm, undermining public health and the advancement of health equity; they must be named, disrupted and corrected.

The fundamental imperative here is to “move healthcare toward justice.” And the way to accomplish that goal is simply to replace “narratives grounded in white supremacy and sustaining structural racism” with morally superior narratives of “critical race theory . . ., gender studies, disability studies, as well as scholarship from social medicine”:

Narratives grounded in white supremacy and sustaining structural racism, for example, perpetuate cumulative disadvantage for some populations and cumulative advantage for white people, and especially white men. Patriarchal narratives enforce rigidly defined traditional norms, and reinforce inequities based on gender. Narratives that uncritically center meritocracy and individualism render invisible the very real constraints generated and reinforced by poverty, discrimination and ultimately exclusion. Yet a rich tradition of work in health equity and related fields, including critical race theory (defined in the glossary), gender studies, disability studies, as well as scholarship from social medicine, gives us a foundation for an alternative narrative, one that challenges the status quo, one that moves health care towards justice.

The AHE Report is 50 pages long, and it never gets any better. “Belief in scientific principles”? Who are they trying to kid?

Funny, but I never heard about any of the CDC staffers who have recently been protesting the firing of Ms. Monarez ever raising a peep about this absurd Report, let alone about CDC venturing into the “climate change” space, or about CDC sticking its nose into gun control.

I say, get rid of them all.

https://www.manhattancontrarian.com/blog/2025-9-4-the-cdc-get-rid-of-it-entirely

BridgeBio Encaleret Shows 80% Success in Hypoparathyroidism Trial



BridgeBio Pharma (Nasdaq: BBIO) announced positive Phase 2 proof-of-concept results for encaleret in treating post-surgical hypoparathyroidism. The study showed that 80% of participants achieved normal blood and urine calcium levels within 5 days of treatment, compared to 0% on conventional therapy.

The oral therapy demonstrated PTH-independent normalization of calcium levels, with nine participants showing rapid and sustained reduction in fractional excretion of calcium. The drug was well-tolerated with no serious adverse events reported. Based on these promising results, BridgeBio plans to initiate a registrational clinical study in 2026.