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Thursday, October 9, 2025

Now They Want to Prescribe Your Food

 Diet should be considered an important part of a patient's treatment along with medication, surgery, and other options, several experts said Wednesday at a "Food Is Medicine" meeting sponsored by Tufts University.

"I would want to see, in 2030, food as a vital sign," said Sean Hashmi, MD, a nephrologist at the Southern California Permanente Medical Group in Woodland Hills. "And if we could do that, if we could make it so simple as ... eat more of this, eat less of this -- it's very basic at its core. And if we as physicians were able to prescribe food as we prescribe an ACE inhibitor, how powerful would that be?"

Although improving diet can be an important component in treating various diseases, it doesn't need to be done in isolation, Hashmi said during the "Food is Medicine in the Era of GLP-1s" panel discussion.

"Sometimes, when we start to talk about things like food as medicine, people automatically assume that you are anti-medications, and it couldn't be further than the truth," he noted. Instead, "we are carpenters. We use the most effective tool when it's needed."

For patients with congestive heart failure, for instance, "we've found by teaching them how to eat better, it's making their medications far more effective," Hashmi said. "We find their ejection fraction improving because their weight is going down. We use GLP-1s all the time in that population, but the combination makes a difference."

Alka Gupta, MD, a Washington internist and board member of the American College of Lifestyle Medicine, shared the story of a 65-year-old patient who walked into her clinic 5 years ago.

"He had just gotten on Medicare, and he came in saying he had no medical problems," she said. "Unfortunately, when he had his first set of blood work done, it revealed a hemoglobin A1c of 11.5%, consistent with floridly uncontrolled type 2 diabetes. This was a devastating diagnosis for him."

"I could tell in that conversation that he was not open to starting insulin," Gupta continued. "He was not open to starting three different medications to bring his blood sugars down. But, together, we decided on a combination approach: intensive lifestyle modification right away, plus, perhaps, medication. We sent him home with a Bluetooth-connected glucometer to check his glucose, and a [Bluetooth-connected] weight scale, so when he checked his sugar or stepped on the scale, our team was able to see it, and we were able to be a bit reassured."

This patient "turned on a dime," she added. "He moved immediately towards a whole-food, plant-forward diet, and he walked an hour per day. Three months later, his hemoglobin A1c was 6.7% and it continued to decrease thereafter. And now -- this is 5 years later -- his diabetes has been in remission for almost the entire time."

He had "self-stopped" his medications within the first 3 months, and continues without them, Gupta said, noting that not only did his chronic low back pain resolve itself, but he now leads a community walking group and shares his story widely.

"If you think about that from the quality-of-life perspective, first and foremost, the rest of his life will likely look very different than had he taken a different path," she said. "And if you look at it from a systemic perspective, I think in the last 5 years, it's very likely that he has avoided at least one, possibly multiple, hospitalizations for high blood sugar. He's sidestepped the potential of side effects or low blood sugars from diabetes or other medications."

Efforts to implement a food-is-medicine approach are being aided by some efforts in Congress and at outside organizations, said Colin Schwartz, MPP, senior advocacy advisor for the American Heart Association's Health Care by Food initiative.

Irrespective of the current government shutdown, "in the fiscal year 2026 appropriations bill ... we had a lot of food-is-medicine wins in it," he said on a separate panel. "It was nice to see, for instance, there was funding for the '[food] prescription' pilots at the Indian Health Service. There's funding for HHS to continue its food-is-medicine collaborative, and language supporting or encouraging establishment of centers of excellence at NIH for food is medicine."

In addition, the NIH Office of Nutrition Research was flat-funded, "and that actually is a win in my book, in this [political] climate," said Schwartz.

In other congressional developments, a bipartisan bill was recently reintroduced that would authorize a demonstration project to provide medically tailored home-delivered meals to Medicare patients in an effort to reduce rehospitalizations, he said. On the regulatory side, the Centers for Medicare & Medicaid Services (CMS) is asking for the public to provide comments on coding and billing for medically tailored meals, "and the House MAHA [Make America Healthy Again] Caucus just sent a letter to CMS asking that Medicare Advantage do more on food-is-medicine. So a lot of progress has been made."

Billing for services related to food-is-medicine -- and defining those services well -- are definitely big issues, said Katie Garfield, director of Whole Person Care at the Center for Health Law and Policy Innovation at Harvard Law School in Boston.

"We don't have billing codes for a lot of these interventions right now, and there has been an incredible effort by the Coding4Food project to create those billing codes," she said. "As part of that process, you're fundamentally also creating a more consistent definition of what these interventions are. And so I'm continuing to think about how we expand that work of definitions and standards that can really make sure that all services are sort of consistent in quality across the country."

https://www.medpagetoday.com/primarycare/dietnutrition/117859

Health-Related Physical Fitness in Patients With Inflammatory Bowel Disease vs Healthy Control

Karlijn Demers, MD, Noortje van den Bergh, BSc, Bart C Bongers, PhD, Sander M J van Kuijk, PhD, Zlatan Mujagic, MD, PhD, Daisy M A E Jonkers, PhD, Marieke J Pierik, MD, PhD, Laurents P S Stassen, MD, PhD


Abstract

Background

Inflammatory bowel disease (IBD) may negatively affect health-related physical fitness. However, the development of interventions to improve health-related physical fitness and thereby disease outcomes is hindered by insufficient evidence. This study compared health-related physical fitness between patients with IBD and healthy control subjects, examined associations with disease and treatment characteristics, and explored patients’ perspectives.

Methods

In this cross-sectional study, 105 patients with IBD and 102 age- and sex-matched healthy control subjects performed validated tests for body fat (4-site skinfold thickness), cardiorespiratory fitness (steep ramp test), muscular strength (steep ramp test, 60-second sit-to-stand test, hand-held dynamometry), muscular endurance (isokinetic dynamometry), and flexibility (sit-and-reach test). Data on disease and treatment characteristics, fatigue, physical activity, and patients’ perspectives were collected.

Results

Patients with IBD had higher body fat (29.5% vs 26.9%; P = .012), lower steep ramp test performance (peak work rate 4.2 W/kg vs 4.8 W/kg; P < .001), fewer sit-to-stand repetitions (42 vs 47; P = .002), and reduced hamstring strength (3.0 N/kg vs 3.2 N/kg; P = .011) compared with healthy control subjects. This was associated with higher age, female sex, higher body mass index, fatigue, arthritis, and multiple biologicals used. Most patients considered physical fitness important and beneficial for their symptoms, and the majority expressed interest in professional support.

Conclusions

Patients with IBD have higher body fat and reduced cardiorespiratory fitness and muscular strength compared with healthy control subjects. Especially, patients with a higher age, female sex, higher body mass index, fatigue, arthritis, or multiple biologicals used are at risk for such impairments and may benefit from physical exercise interventions.


https://academic.oup.com/ibdjournal/advance-article/doi/10.1093/ibd/izaf169/8277594

Risk of Clostridioides difficile Infection After Helicobacter pylori Treatment

Lawrence J. Leung, MD, MPH1,∗ ∙ Sophie A. Merchant, MPH2,∗ ∙ Jessica M. Badalov, MPH2 ∙ Douglas A. Corley, MD, PhD1,2 ∙ Dan Li, MD

Abstract

Background and Aims

Adverse outcomes associated with the treatment of Helicobacter pylori (H. pylori) remain poorly understood. We investigated whether H. pylori treatment was associated with an increased risk of Clostridioides difficile infection (CDI).

Methods

This retrospective cohort study included all adult members who tested positive for H. pylori between 1/1/2000 and 12/31/2020 at Kaiser Permanente Northern California. We measured the incidence of CDI after H. pylori treatment and evaluated the predictors of CDI using multivariable logistic regression.

Results

Of 139,226 individuals who tested positive for H. pylori, the incidence of CDI was 5.9/10,000 within 3 months (P=0.02) and 7.0/10,000 (P=0.003) within 6 months after H. pylori treatment, compared with 2.7/10,000 among untreated individuals. The adjusted odds ratio (aOR) (95% confidence interval [CI]) for CDI within 3 months after H. pylori treatment was 2.00 (1.02-3.90) overall, 3.15 (1.14-8.70) for concomitant therapy and 6.34 (2.75-14.59) for bismuth quadruple therapy. Inflammatory bowel disease (IBD) (aOR 7.89 [2.38-26.21]) and history of CDI (aOR 8.27 [1.92-35.62]) had the strongest association with CDI, while Asians/Pacific islanders (aOR 0.22 [0.09-0.55] and non-English language preference (aOR 0.30 [0.12-0.72]) were associated with a lower risk.

Conclusions

In a large, diverse, community-based population, treatment of H. pylori was associated with an increased risk of CDI, although the overall incidence was very low. History of IBD and prior CDI were the strongest predictors of CDI. These findings support the safety of H. pylori treatment, although caution should be exercised when treating H. pylori among individuals with IBD or prior history of CDI.



'California Aims to Improve School Nutrition by Phasing Out Some Ultraprocessed Foods'

 California will phase out certain ultraprocessed foods from school meals over the next decade under a first-in-the-nation law signed Wednesday by Gov. Gavin Newsom.

The law seeks to define ultraprocessed foods, the often super-tasty products typically full of sugar, salt, and unhealthy fats. The legislation requires the state's Department of Public Health to adopt rules by mid-2028 defining "ultraprocessed foods of concern" and "restricted school foods."

Schools have to start phasing out those foods by July 2029, and districts will be barred from selling them for breakfast or lunch by July 2035. Vendors will be banned from providing the "foods of concern" to schools by 2032.

Newsom, flanked by first partner Jennifer Siebel Newsom and state lawmakers, signed the measure at a middle school in Los Angeles.

"California has never waited for Washington or anyone else to lead on kids' health -- we've been out front for years, removing harmful additives and improving school nutrition," Newsom said in a statement. "This first-in-the-nation law builds on that work to make sure every California student has access to healthy, delicious meals that help them thrive."

Newsom issued an executive order earlier this year requiring the Department of Public Health to provide recommendations by April on limiting harms from ultraprocessed foods. The Democratic governor signed a law in 2023 banning certain synthetic food dyes from school meals.

Legislatures across the country have introduced more than 100 bills in recent months seeking to ban or require labeling of chemicals that make up many ultraprocessed foods, including artificial dyes and controversial additives.

Americans get more than half their calories from ultraprocessed foods, which have been linked to a host of health problems, including obesity, diabetes, and heart disease. However, studies haven't been able to prove that the foods directly cause those chronic health problems.

Defining Ultraprocessed Foods

Defining ultraprocessed foods has been tricky. The most common definition is based on the four-tier Nova system developed by Brazilian researchers that classifies foods according to the amount of processing they undergo.

Researchers often describe ultraprocessed foods as the types of products that contain industrially made ingredients that you won't find in a home kitchen.

But some highly processed foods -- think tofu, certain types of whole-grain bread, and infant formula -- can be healthful. And it's not clear whether it's the processing of the foods or the combination of nutrients such as sugar, fat, and salt that leads to poor health outcomes.

U.S. health officials recently launched an effort to come up with a federal definition of ultraprocessed foods, saying there are concerns over whether current definitions "accurately capture" the range of foods that may affect health.

Some Say California's Ban Goes Too Far

Some critics of the ban say it is too broad and could unintentionally limit access to nutritious foods.

"For foods served in schools, food and beverage manufacturers meet the rigorous unique safety and nutrition standards set by the [U.S. Department of Agriculture] and state agencies," John Hewitt with the Consumer Brands Association said in a statement. He added the brands the association represents are committed to "providing safe, nutritious, and convenient" products.

The California School Boards Association is concerned about the cost for districts to phase out these foods in the next few years. There is no extra money attached to the bill.

"You're borrowing money from other areas of need to pay for this new mandate," spokesperson Troy Flint said.

The law could raise costs for school districts by an unknown amount by potentially making them purchase more expensive options, according to an analysis by the Senate Appropriations Committee.

Some Districts Already Overhauling School Menus

Some school districts in California are already phasing out foods the law seeks to ban.

Michael Jochner spent years working as a chef before taking over as director of student nutrition at the Morgan Hill Unified School District about 8 years ago. He fully supports the ban.

"It was really during COVID that I started to think about where we were purchasing our produce from and going to those farmers who were also struggling," he said.

Now they don't serve any ultraprocessed foods, and all their items are organic and sourced within about 50 miles (80 kilometers) of the district, Jochner said. They removed sugary cereals, fruit juices and flavored milks, and deep-fried foods such as chicken nuggets and tater tots from their menus, he said.

Many of their dishes are made from scratch or semi-homemade, including an item that has long been a staple in U.S. school cafeterias: pizza.

Pizza is also a popular option for students in the Western Placer Unified district northeast of Sacramento, where Director of Food Services Christina Lawson has spent the past few years introducing more meals made from scratch to their school menus.

She estimates up to 60% of school menus in the district are made up of dishes made from scratch, up from about 5% three years ago. They also purchase more foods locally to prepare a wide variety of items, including buffalo chicken quesadillas using tortillas made in nearby Nevada City.

"I'm really excited about this new law because it will just make it where there's even more options and even more variety and even better products that we can offer our students," Lawson said. "Because variety is the number one thing our students are looking for."

Ravinder Khaira, MD, a pediatrician in Sacramento who supports the law, said at a legislative hearing that the ban will help respond to a surge of chronic conditions in children fueled by poor nutrition.

"Children deserve real access to food that is nutritious and supports their physical, emotional, and cognitive development," Khaira said. "Schools should be safe havens, not a source of chronic disease."

https://www.medpagetoday.com/primarycare/dietnutrition/117866

Trump Vows Military Will Be Paid; IRS Furloughs Half Of Staff As Shutdown Enters Day 9

 With day nine of the federal government shutdown upon us and no end in sight after the Senate rejected both Republican and Democratic plans to reopen (their 6th failed vote), President Donald Trump doubled down on threats to block some furloughed federal workers from receiving back pay once the shutdown is over - but insisted that members of the military don't have to worry about missing their next paychecks - signaling support for standalone legislation to ensure they're paid. 

Republican Rep. Ken Calvert - who's in charge of defense funding, has also thrown his weight behind the bill, which was introduced by Rep. Jen Kiggans (R-VA) in mid-September, and has been gaining steam since the shutdown began Oct. 1. 

House Democratic leadership supports the standalone bill to ensure military troop payments. 

In a Thursday morning C-SPAN interview, meanwhile, House Speaker Mike Johnson (R-LA) took several calls from unhappy Americans - one of whom was a military wife from Virginia, who pleaded with him to reopen the government or pass funding so her family doesn't miss a paycheck on Oct 15. 

"As a Republican, I'm very disappointed in my party, and I'm very disappointed in you, because you have the power to call the House back," she said. "You refuse to do that, just for a show."

Johnson replied that situations like hers keep him up at night (lol sure), and that the House already tried to vote to pay the troops when it passed a short-term government funding extension that the Senate refuses to pass.

"The Democrats are the ones that are preventing you from getting a check," Johnson said. 

Meanwhile, the IRS on Wednesday announced that it would furlough some 34,000 employees - nearly half the agency's staff, adding to the approximately 750,000 furloughed workers government-wide. 

Payday Looms

On Friday, federal employees should expect smaller paychecks, which covers work between Sept. 21 and Oct. 4, so they'll only be paid for work between Sept. 21 and Oct. 1. 

Under the 2019 Government Employee Fair Treatment Act, federal workers should receive retroactive pay after the shutdown - however a leaked internal memo revealed that the Trump administration interpreted the Act to place the responsibility on Congress to authorize payments. 

https://www.zerohedge.com/political/trump-vows-military-will-be-paid-irs-furloughs-34000-employees-shutdown-enters-day-9

Cabaletta Bio Inc reports new data from RESET-PV trial

 Cabaletta Bio (CABA) has unveiled promising initial data from the RESET-PV trial, which evaluated rese-cel at a dosage of 1 x 106 cells/kg without the use of preconditioning treatments in patients with pemphigus vulgaris. This information was highlighted in a late-breaking oral presentation by Cabaletta's Chief Scientific Officer, Dr. Samik Basu, at the 2025 European Society of Gene & Cell Therapy Annual Congress in Seville, Spain.

The trial is a pioneering study in Cabaletta's RESET program, as it assesses the potential of rese-cel without relying on cyclophosphamide and fludarabine for preconditioning. Key insights from the data cut-off date of September 11, 2025, revealed that rese-cel demonstrated similar kinetics in CAR T cell expansion and contraction compared to other RESET trials that included preconditioning.

Notably, all three patients experienced significant B cell depletion soon after infusion. Patients 2 and 3 achieved complete depletion, alongside a marked reduction in autoantibodies and manageable levels of B cell activating factor. Rese-cel was well-tolerated, with no reports of neurotoxicity. Patient 1 had a temporary fever, while Patient 2 required steroids for a mild flare but later tapered off.

Encouraging clinical responses were observed within the first month, as reflected in improved Pemphigus Disease Area Index (PDAI) scores. Patient 1's score dropped from 24 to 10, Patient 2 from 83 to 3, and Patient 3 from 22 to 2. These scores suggest significant skin and mucosal improvements, supporting further exploration of preconditioning removal in the RESET program.

https://www.gurufocus.com/news/3137747/cabaletta-bio-caba-reports-positive-initial-results-from-resetpv-trial

GE Healthcare Unveils Carestation 850 At Anesthesiology 2025

 

  • Carestation 850 is designed to help health systems navigate the evolving landscape of anesthesia care now and in the future with an ergonomic design, continuously optimized algorithms, adaptable technologies and sustainable practices.

  • With the goal of enhancing clinical precision, Carestation 850 features tools and customizable applications that are designed to help adapt to the needs of each patient, from neonates to the elderly.

  • GE HealthCare will showcase Carestation 850 at booth #1314 during ANESTHESIOLOGY 2025 taking place from October 10-14, in San Antonio, Texas.

GE HealthCare (Nasdaq: GEHC) today announced the unveiling of Carestation™ 850, its next-generation, FDA 510(k) pendingi anesthesia delivery system that is designed to help care teams adapt to evolving clinical and operational needs. Marking the latest evolution of GE HealthCare’s Carestation portfolio, Carestation 850 has the potential to advance anesthesia care through tools, customizable applications, and a sleek, space conscious footprint. The FDA 510(k) submission for Carestation 850 follows the recent CE mark in Europe and Australian Therapeutic Goods approval in Australia and New Zealand.

Anesthesia professionals today are facing more demands, as health systems grapple with a high volume of increasingly complex surgical cases.ii This strain is faced across the anesthesia field, including anesthesiologists, clinical registered nurse anesthetists and anesthesia assistants. An estimated 68% of anesthesia professionals are at high risk of burnout, contributing to high turnover and staffing shortages across the industry.iii,iv,v These trends are expected to continue, with the anesthesiologist shortage projected to reach 12,500 by 2033, underscoring the need for more efficient care delivery

https://finance.yahoo.com/news/ge-healthcare-unveils-carestation-850-120000590.html