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Friday, February 22, 2019

Karyopharm socked by FDA briefing docs

“The combination of selinexor and dexamethasone demonstrated limited efficacy and significant toxicity in patients with relapsed/refractory multiple myelom (RRMM),” concludes the FDA.
“Given the limited efficacy and significant toxicity demonstrated in this population, it is unclear whether treatment with selinexor-dexamethasone provides a clinically meaningful benefit that outweighs the risks of treatment. “

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