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Friday, May 31, 2019

Turning Point Therapeutics Updates Lung Cancer Data

  • In TKI-naïve ROS1+ Patients, Overall Response Rate by Blinded Review is 82 Percent, and 83 Percent at Likely Recommended Phase 2 Dose of 160 mg QD or Above; Median Duration of Response across all Dose Levels Not Yet Reached
  • Since Prior Update, Overall Response Rate by Blinded Review Increased in ROS1+ Patients Pretreated with one Prior TKI to 39 percent and to 55 Percent at Doses of 160 mg QD or Above
  • All Five ROS1+ Crizotinib-Pretreated Patients with G2032R Solvent Front Mutation had Tumor Regressions, and Overall Response Rate by Blinded Review is 40 Percent
  • Phase 2 Portion of TRIDENT-1 Registrational Study on Track for Initiation in 2H 2019
  • Company Files 10-Q and Provides Financial Update

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