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Tuesday, August 11, 2020

Bristol-Myers’ Opdivo successful in two late-stage studies

Bristol-Myers Squibb (NYSE:BMY) announces positive results from two Phase 3 clinical trials involving PD-1 inhibitor Opdivo (nivolumab).
CheckMate-577: Opdivo as adjuvant therapy in patients with resected esophageal or gastroesophageal junction (GEJ) cancer. The primary endpoint of disease-free survival (DFS) was met at a prespecified interim analysis.
CheckMate-649: Opdivo plus chemo compared to chemo alone for the first-line treatment of metastatic gastric cancer, GEJ or esophageal adenocarcinoma. Both primary endpoints, overall survival (OS) and progression-free survival (PFS), were met.
Results will be shared with health authorities and presented at upcoming medical conferences.

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