Susceptibility of SARS-CoV-2 to UV Irradiation

Christiane SilkeHeilingloh¹Ulrich WilhelmAufderhorst¹²LeonieSchipper¹UlfDittmer²⁵OliverWitzke¹DongliangYang³⁴XinZhe

ng³⁴KathrinSutter²⁴MirkoTrilling²⁴MiraAlt¹EikeSteinmann⁵*AdalbertKrawczyk¹²⁵

https://doi.org/10.1016/j.ajic.2020.07.031

PDF: https://www.sciencedirect.com/science/article/pii/S0196655320307562/pdfft?md5=8618b80b3c2d3d92f50f8767c374cfd5&pid=1-s2.0-S0196655320307562-main.pdf

Highlights

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SARS-CoV-2 is highly susceptible to irradiation with ultraviolet light

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High viral loads of 5 *10⁶ TCID₅₀/ml SARS-CoV-2 can be inactivated in 9 minutes by UVC irradiation

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UVC irradiation represents a suitable disinfection method for SARS-CoV-2

Abstract

The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10⁶ TCID₅₀/ml was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1048 mJ/cm². UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose.

https://www.sciencedirect.com/science/article/pii/S01966