Cara misses primary endpoint in Phase 2 dermatitis trial

 Study did not meet Primary Endpoint of worst-itch NRS change from baseline at

week 12 or Secondary Endpoint of 4-point responder analysis in the ITT patient population

– Study achieved Primary Endpoint of worst-itch NRS change and Secondary Endpoint of 4-point responder analysis in pre-specified analyses of mild-to-moderate AD patients (64% of ITT patient population) –

– Statistically significant improvement in 4-point responder analysis in
mild-to-moderate (BSA <10%) AD patients with 32% of KORSUVA-treated patients achieving a > 4-point reduction vs. 19% in placebo group (p=0.03) –

– KORSUVA was well tolerated at all dose levels –

– Company to host conference call today at 8:00 a.m. ET –

To participate in the conference call, please dial (800) 708-4539 (domestic) or (847) 619-6396 (international) and refer to conference ID 50157934. A live webcast of the call can be accessed under "Events & Presentations" in the News & Investors section of the Company's website at www.CaraTherapeutics.com.

An archived webcast recording will be available on the Cara website beginning approximately two hours after the call.

https://finance.yahoo.com/news/cara-therapeutics-announces-topline-results-110000707.html