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Wednesday, January 5, 2022

Pfizer and BioNTech to Develop First mRNA-based Shingles Vaccine

 

  • Third mRNA vaccine collaboration between the companies aims to accelerate development of an improved vaccine for shingles, a debilitating, disfiguring and painful disease that affects people all over the world

  • Product candidates will be based on BioNTech’s proprietary mRNA technology and on Pfizer’s antigen technology

  • Clinical trials are expected to start in the second half of 2022

  • BioNTech will receive $225 million upfront, including an upfront cash payment of $75 million and an equity investment of $150 million, and will be eligible to receive future approval and sales milestone payments totaling up to $200 million as well as a share of gross profits arising from future product sales

  • Pfizer will receive an upfront payment of $25 million from BioNTech for its proprietary antigen sequences identified by Pfizer

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