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Monday, April 4, 2022

Ionis: Positive data for ETESIAN Phase 2b study of antisense med targeting PCSK9 at ACC

 

  • ETESIAN Phase 2b study of ION449 (AZD8233) met its primary and secondary endpoints; ION449 was generally well tolerated
  • ION449 demonstrated potential best-in-class efficacy profile for a self-administered subcutaneous monthly dose regimen
  • Study findings warrant further clinical development of ION449 for patients with hypercholesterolemia at high cardiovascular risk

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