Horizon: Candidate Effective in Neuromyelitis Optica Spectrum Disorder Phase 3

 Horizon Therapeutics plc (Nasdaq: HZNP) today announced new findings from a post hoc analysis of the N-MOmentum Phase 3 pivotal trial of UPLIZNA supporting the medicine’s efficacy in Europeans living with NMOSD. These data are being presented during the 8^th Congress of the European Academy of Neurology (EAN), June 25-28 in Vienna.

UPLIZNA received marketing authorization from the European Commission (EC) on April 25, 2022 and is the first and only targeted CD19+ B-cell-depleting monotherapy proven to reduce attacks in adult patients with NMOSD who are anti-aquaporin-4 immunoglobulin G seropositive (AQP4-IgG+). This post hoc analysis compared attack rates, disability-related outcomes and safety among 50 trial participants from the European Union (EU) (including participants from Bulgaria, Czech Republic, Estonia, Germany, Hungary and Poland) versus 163 non-EU participants.

https://www.biospace.com/article/releases/new-analysis-finds-uplizna-inebilizumab-effective-among-european-populations-with-neuromyelitis-optica-spectrum-disorder-nmosd-/