uniQure Update on Low-Dose Cohort in Phase I/II Trial of Gene Therapy for Huntington’s

  Treatment generally well-tolerated with no significant safety issues related to AMT-130 in treated patients through one year of follow-up ~

~ A mean reduction of 53.8% of mutant HTT (mHTT) observed in cerebral spinal fluid (CSF) at 12 months in evaluable patients treated with AMT-130 ~

~ Neurofilament Light Chain (NfL) in CSF near baseline at 12 months in patients treated with AMT-130 ~

~ Biomarker and clinical data including 24-month follow-up in the low-dose U.S. cohort and 12-month follow up in the high-dose U.S. cohort expected in first half of 2023 ~

~ Investor conference call and webcast today at 8:30 a.m. ET ~

uniQure management will host an investor conference call and webcast today, Thursday, June 23, 2022, at 8:30 a.m. ET. The conference call may be accessed by dialing (833) 962–1472 for domestic callers and (442) 268-1254 for international callers. The conference call ID is 3873647. Please specify to the operator that you would like to join the “uniQure Conference Call.” If you are joining the conference call, please dial-in 15 minutes before the start time. The webcast of the conference call may also be accessed through the Investors & Newsroom section of the uniQure website. Following the live webcast, a replay of the call will be archived for several weeks.

https://www.biospace.com/article/releases/uniqure-announces-update-on-low-dose-cohort-in-phase-i-ii-clinical-trial-of-amt-130-gene-therapy-for-the-treatment-of-huntington-s-disease/