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Friday, September 29, 2023

Gene therapy biotech Lexeo Therapeutics files for a $100 million IPO

 

Lexeo Therapeutics, a Phase 1 biotech developing gene therapies for cardio and neuro diseases, filed on Friday with the SEC to raise up to $100 million in an initial public offering.

Lexeo Therapeutics is a genetic medicine company focused on fundamentally changing how disease is treated by pioneering science. The company's most advanced cardiovascular candidate, LX2006, is being developed for Friedreich's ataxia (FA) cardiomyopathy and is currently being evaluated in an ongoing Phase 1/2 trial. It expects to report additional interim data from this trial in mid-2024. Lexeo's lead Alzheimer's disease candidate, LX1001, is being developed for the treatment of APOE4 homozygous patients with Alzheimer's disease and is in an ongoing Phase 1/2 trial. It expects to complete enrollment in the trial by the end of 2023 and report additional interim data from all cohorts in the Phase 1/2 trial in the 2H24.

The New York, NY-based company was founded in 2017 and booked $1 million in grant revenue for the 12 months ended June 30, 2023. It plans to list on the Nasdaq under the symbol LXEO. Lexeo Therapeutics filed confidentially on February 4, 2022. J.P. Morgan, Leerink Partners, Stifel, and RBC Capital Markets are the joint bookrunners on the deal. No pricing terms were disclosed.

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