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Tuesday, March 5, 2024

Apogee Positive Results in Atopic Dermatitis Trial

 Positive interim results from APG777 Phase 1 healthy volunteer clinical trial exceeded objectives with approximately 75-day half-life which supports the potential for higher exposures leading to potential for improved clinical responses in induction than currently available biologic therapies and the potential for maintenance dosing of every 3- or 6-months


APG777 Phase 1 interim data support advancement of a randomized, placebo-controlled Phase 2 clinical trial in patients with moderate-to-severe atopic dermatitis in 1H 2024 ahead of schedule


Phase 1 healthy volunteer clinical trial set to start ahead of schedule for APG808, a subcutaneous extended half-life antibody targeting IL-4Rα, following receipt of regulatory clearance in February


Total cash of $395.5 million at year end 2023 with expected cash runway into 4Q 2026

https://www.globenewswire.com/news-release/2024/03/05/2840236/0/en/Apogee-Therapeutics-Provides-Pipeline-Progress-and-Reports-Fourth-Quarter-and-Full-Year-2023-Financial-Results.html

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