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Saturday, June 22, 2024

Amylyx to buy bankrupt Eiger's experimental drug to treat low blood sugar

 Amylyx Pharmaceuticals has agreed to buy the rights to bankrupt drugmaker Eiger BioPharmaceuticals' experimental drug for low blood sugar in a $35.1 million deal, Eiger said in a filing on Friday.

Amylyx's acquisition of avexitide would mean a foray into drug development for metabolic diseases. The company had so far been a developer of drugs to treat neurodegenerative diseases.

Avexitide is a GLP-1 antagonist drug that help treat low blood sugar, the opposite of what diabetes and weight-loss medicines such as Novo Nordisk's Ozempic and Wegovy, and Eli Lilly's Mounjaro and Zepbound do.

In April, Amylyx announced its plans to remove Relyvrio - its approved drug for amyotrophic lateral sclerosis (ALS) - from the market after failing in a key late-stage trial.

Amylyx did not immediately respond to Reuters' request for comment.

Eiger has tested avexitide in mid-stage studies as a potential treatment for low blood sugar caused by bariatric surgery and also a metabolic disorder called congenital hyperinsulinism.

Congenital hyperinsulinism occurs in newborns and causes permanent brain damage and life-long insulin-dependent diabetes.

Separately, Eiger had filed for Chapter 11 bankruptcy in April.

https://www.yahoo.com/news/amylyx-buy-bankrupt-eigers-experimental-220712782.html

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