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Monday, June 3, 2024

ASCO: Sarclisa 1st anti-CD38 to improve progression-free survival in combo for multiple myeloma

 

  • Sarclisa, in combination with standard-of-care bortezomib, lenalidomide and dexamethasone (VRd) followed by Sarclisa-Rd reduced the risk of recurrence or death by 40% versus VRd followed by Rd in the investigational use for transplant-ineligible newly diagnosed multiple myeloma patients
  • Key primary endpoint of progression-free survival met, demonstrating Sarclisa's potential as a first-in-class combination to address gaps in care for newly diagnosed transplant-ineligible patients
  • Full data simultaneously published in NEJM and formed the basis of regulatory submissions

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