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Wednesday, January 8, 2025

Johnson & Johnson Gets FDA Fast-Track Designation for Posdinemab in Alzheimer's

 Johnson & Johnson on Wednesday said it has won Food and Drug Administration fast-track designation for its proposed posdinemab treatment for Alzheimer's disease.

J&J is investigating the internally discovered tau-directed monoclonal antibody in a Phase 2b study of patients with early Alzheimer's.

The New Brunswick, N.J., pharmaceutical giant said posdinemab has shown potential in targeting disease-associated phosphorylated tau in cerebrospinal fluid from treated Alzheimer's patients, and in blocking the development and spread of tau aggregates in non-clinical models of the memory-robbing disease.

The FDA's fast-track program is designed to facilitate the development and expedite the review of treatments for serious or potentially life-threatening illnesses with high unmet medical needs.

The FDA last year granted fast-track designation to J&J's anti-tau active immunotherapy JNJ-2056.

https://www.morningstar.com/news/dow-jones/202501084168/johnson-johnson-gets-fda-fast-track-designation-for-posdinemab-in-alzheimers

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