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Wednesday, January 15, 2025

OS Therapies Phase 2b Trial Statistical Significance to Prevent Lung Metastatic Osteosarcoma

 

  • The primary endpoint of 12-month Event Free Survival (EFS) for OST-HER2- treated patients (33.3%) was statistically significant (p= 0.0158) when compared with peer-reviewed comparable historical control (20%)

  • Ongoing follow up demonstrates strong trend in favor of OST-HER2 in 1-year and 2-year interim analyses of the secondary endpoint, 3-year overall survival (OS) when compared with comparable peer-reviewed historical control

  • 100% of patients who achieved 12-month EFS remain alive in OS follow-up

  • OST-HER2 was safe and well tolerated in the Phase 2b study

  • OS Therapies reiterates clinical and regulatory path in recurrent, fully resected osteosarcoma with lung metastases, an indication with no currently approved treatments

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