Alloy Therapeutics Establishes Multi-Year Collaboration With Pfizer

 Collaboration builds on Alloy’s existing and highly productive engagement with Pfizer and will apply Alloy’s innovation expertise to address Pfizer’s specific antibody discovery objectives

Alloy Therapeutics Inc. ("Alloy"), a biotechnology ecosystem company dedicated to democratizing access to cutting edge drug discovery technologies, announced today its latest strategic collaboration with Pfizer Inc., to develop a new platform that could enhance Pfizer’s ability to discover potent, specific, and effective antibodies against targets that are difficult to address with existing antibody discovery technologies. Under the terms of the collaboration, Alloy will receive an upfront payment from Pfizer and will be eligible for pre-specified preclinical to commercial milestones on products originating from the newly developed platform.

"Pfizer has leveraged our industry-leading ATX-GxTM platform for several years, and we collaborated closely with them to develop the common light chain ATX-CLC strains. This collaboration exemplifies how pharma can leverage Alloy’s technology and expertise broadly in antibody discovery and technological innovation by participating in the creation of pre-competitive tools," said Heather Schwoebel, Chief Business Officer, Antibodies and Head of Strategic Collaborations at Alloy. "We will now apply this expertise to jointly create a new platform that enhances Pfizer’s ability to develop antibodies against challenging high-value targets. We are proud to expand our collaboration with Pfizer in the fight against disease."

Alloy’s ATX-Gx platform has rapidly become the industry standard for fully humanized transgenic mice, being used by over 170 partners and in turn enabling many therapeutic discovery programs. Alloy is dedicated to reinvesting its revenue into innovation and has continuously expanded its murine platforms, adding new strains such as ATX-GLTM with the full human lambda repertoire, as well as ATX-GKHTM hyperimmune strain for increased generation of antigen-specific B-cells and enhanced IgG class switching.

https://finance.yahoo.com/news/alloy-therapeutics-establishes-multi-collaboration-133000615.html