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Sunday, June 1, 2025

ASCO: Bicara Therapeutics Demonstrates Deep and Durable Responses in Head & Neck Cancer

 

  • Bicara Therapeutics' Phase 1/1b trial for ficerafusp alfa combined with pembrolizumab shows promising results in HPV-negative head and neck cancer.
  • Key findings include a 54% objective response rate, 21% complete response rate, and a median duration of response of 21.7 months.
  • Ficerafusp alfa exhibits a manageable safety profile, supporting its continued development in the FORTIFI-HN01 Phase 2/3 trial.

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