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Wednesday, June 25, 2025

Hoth-Silo jv for GDNF therapy licensed from U.S. Veterans Affairs targets obesity, fatty liver disease



Hoth Therapeutics (NASDAQ: HOTH) and Silo Pharma (NASDAQ: SILO) have formed a 50/50 joint venture to develop and commercialize a novel obesity treatment licensed from the U.S. Department of Veterans Affairs. The therapy is based on Glial Cell Line-Derived Neurotrophic Factor (GDNF), targeting obesity and non-alcoholic fatty liver disease (NAFLD).

The technology, protected under U.S. Patent No. 10,052,362, aims to address a $100B+ market with potential applications for type 2 diabetes and central obesity. The partnership combines the VA's clinical infrastructure, Hoth's regulatory expertise, and Silo's translational capabilities to develop this first-in-class treatment targeting the neuroinflammatory root of obesity.

https://www.stocktitan.net/news/HOTH/hoth-therapeutics-hoth-and-silo-pharma-nasdaq-silo-today-announced-9wumkyqaag4d.html

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