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Wednesday, May 6, 2026

Myriad misses, reaffirms 2026 outlook as cancer, GeneSight offset prenatal weakness

 

Myriad misses Q1 2026 estimates with EPS -$0.09, revenue $200.4M, but reaffirms 2026 outlook as cancer, GeneSight offset prenatal weakness

  • Reported Q1 2026 GAAP loss of $0.36 per share alongside adjusted loss of $0.09 per share.
  • Q1 results missed Zacks consensus estimates for both adjusted EPS and revenue.
  • Q1 revenue $200.4M, +2% YoY and within guidance; total tests 385,000, flat YoY.
  • Hereditary cancer volumes +14% YoY (affected +10%, unaffected +16%), driving Cancer Care Continuum revenue +4%.
  • Prenatal revenue $41.9M, -15% YoY; volumes slightly up QoQ but softer than internal expectations.
  • GeneSight revenue $38.3M, +24% YoY on 7% volume growth and improved reimbursement; 39k+ ordering clinicians.
  • Gross margin 68.7%, ~20 bps higher YoY and in line with 68–69% full‑year guidance.
  • Adjusted EBITDA loss $5M and adjusted EPS loss $0.09, both hurt by accelerated commercial hiring.
  • Full‑year 2026 guidance reaffirmed: revenue $860–880M, adjusted EBITDA $37–49M, implying stronger 2H ramp.
  • Company added 100+ account executives, mainly in oncology; dedicated prenatal and hereditary sales teams now in place.
  • Precise MRD breast alpha launch tracking well; colorectal and renal alpha launches pulled forward into Q3 2026.
  • FirstGene prenatal test on track for 2H 2026 launch; expected to be ASP and margin accretive.
  • Main concern: Execution risk on the back‑half growth ramp, especially prenatal reacceleration and new product launches underpinning guidance.
  • Mixed quarter, driven by strong hereditary cancer and GeneSight growth offset by prenatal weakness and heavier upfront investments.

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