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Saturday, February 12, 2022

The Fed must control Inflation for public safety's sake

 Recently, the Federal Reserve announced new interest rate hikes to curb the rampant inflation we’ve seen over the last several months. That’s an important step, because what happens to a society when consumer prices skyrocket is not a pretty picture.

We have vivid historical examples of the havoc that runaway inflation can cause: Germany immediately after the First World War, Argentina during most of the past four decades, Venezuela after the election of President Nicolás Maduro in 2013. In each instance, mass suffering ensued, political conflict increased, civil disorder spread, and crime rates rose.

While these cases each saw inflation at far greater levels than we currently have, more modest price increases can also spark crime and social strife. U.S. crime rates rose sharply during the period of sustained inflation in the 1970s. With inflation now running at a 40-year high, price stability needs to become a top policy priority of the Biden administration to avoid a similar fate.

Rising prices increase both nonviolent and violent crime. Inflation drives up so-called acquisitive crime — offenses committed for monetary gain. Inflation reduces purchasing power, especially when incomes fail to keep pace with rising prices. As prices increase, consumers “trade down” to discount outlets in search of cheaper goods. Some enter the market for stolen goods. Expanding underground markets increase incentives for the robbers and thieves who supply the goods and crime rates rise.

Violent crime, including homicide, is also elevated in underground markets. Stolen goods markets are “stateless”, bringing together sellers and buyers who lack formal ways to settle disputes over the price, quantity, and quality of goods. Those who possess stolen goods also risk attack by street robbers. As the traffic in stolen goods increases, therefore, violence does as well.

Both acquisitive crime and homicide rates have risen and fallen together with inflation for the past half century in U.S. cities. Our research shows that homicide increases are greatest in the most economically disadvantaged cities. In some cities (e.g., Atlanta, Boston, and New York), inflation first increases crimes like robbery, burglary, and theft which, in turn, lead to increases in homicide. But elsewhere the effect of inflation on homicide rates occurs through other means, including declining trust in social institutions.

Rampant inflation has momentous effects on public trust, social order, and political stability. In fact, rising rates of inflation were one cause of the plummeting confidence in American institutions during the quarter century separating the prosperous 1960s and the early 1990s.  Political analyst Michael Tomasky has written that the hyperinflation of the 1970s in the United States “was as pivotal a factor in our national crackup as Vietnam and Watergate.”

Institutional trust is again at historically low levels. According to the PEW Research Center, only about a quarter of Americans currently trust the federal government to do what is right “just about always” or “most of the time.”

Lack of confidence in the federal government might seem to be a distant and insubstantial source of the often mundane tensions, disputes, and grievances that give rise to homicide. Yet, as research by historian Randolph Roth has shown, feelings and beliefs about the interests and identities served by those in power can have fearsome consequences for everyday life. Distrust sows discontent, hostility, and conflict—the preconditions for violence.

Inflation has more immediate, direct, and widespread consequences for economic wellbeing than any other economic factor, especially for those of modest means. A rise in unemployment poses obvious difficulties for the jobless, but most people remain employed even during economic downturns. Except for the very wealthy or business owners who can adjust their own prices, inflation affects everyone.

For these reasons, price stability is a key public policy priority. It is one of the three central objectives of the Federal Reserve, along with maximum employment and moderate long-term interest rates.

Given the substantial evidence showing that inflation increases crime, public safety must now also be a direct objective of U.S. monetary policy, particularly when it comes to preventing steep and prolonged price increases. The Fed lists among its purposes “promoting consumer protection and community development.” Fighting inflation and increasing public safety serves both ends. 

Richard Rosenfeld is Curators’ Distinguished Professor Emeritus of Criminology and Criminal Justice at the University of Missouri-St. Louis. He is a Fellow and past president of the American Society of Criminology. Matt Vogel is Associate Professor of Criminal Justice at the University at Albany and a faculty affiliate in the Department of Sociology and the Center for Social and Demographic Analysis.

https://thehill.com/blogs/congress-blog/economy-budget/593957-the-fed-must-control-inflation-for-public-safetys-sake

Canadian Police Arrive To 'Remove' Freedom Convoy Protesters From Ambassador Bridge

 Following Friday's 'state of emergency' declaration in Ontario, which empower police to finally clear the protesters blocking the Ambassador Bridge (of course, the Canadian government could have just rolled back the COVID restrictions that inspired the protests to begin with, although Prime Minister Justin Trudeau has used some truly bizarre rhetoric in its defense), Canadian police have moved in early Saturday to start making arrests and breaking the protest.

Protesters at the busiest land crossing between the US and Canada staunchly remained overnight despite the threats of violence from the Canadian government. The blockade has forced auto makers in the US to shutter production due to a shortage of parts (while some have been forced to fly parts across the border).

According to the AP, a city bus and school bus with the police arrived on scene Saturday morning, and officers got in formation to start clearing out the protesters.

A city bus and school bus arrived at the scene Saturday morning and police moved in formation toward them. But the protesters remained defiant.

Windsor police immediately warned that anyone blocking the streets could be subject to arrest and their vehicles could be seized.

The news was met earlier with defiance by protesters.

At the Ambassador Bridge, an unidentified person grabbed a microphone and addressed the crowd, asking if they wanted to stay or leave when the deadline rolled around. By a show of applause, it was agreed they would stay. “OK,” the man said. “Let’s stand tall.” The protesters responded by singing the Canadian national anthem.

Using a megaphone, one of the protesters alerted the others that police were coming for the demonstrators. Video of the situation quickly made its way online courtesy of @JackPosobiec.

Meanwhile, the police tweeted the following message: "The Windsor Police & its policing partners have commenced enforcement at and near the Ambassador Bridge. We urge all demonstrators to act lawfully & peacefully. Commuters are still being asked to avoid the areas affected by the demonstrations at this time."

A judge on Friday ordered the protesters to clear the bridge, but an injunction issued b Chief Justice Geoffrey Morawetz of the Ontario Superior Court gave them until 1900ET on Friday to clear out. But the deadline came and went without any movement by the protesters.

On Friday, Ontario Premier Doug Ford declared a state of emergency in the province that will allow his cabinet to impose $100,000 fines and up to one year in jail as punishments against anybody blocking roads, bridges or other infrastructure.

As we have pointed out before, the "Freedom Convoy" protests in Canada have spread to three distinct border areas.

After initially being blocked by the police, reporters with Rebel News have managed to get through and join MSM reporters in covering the showdown between the protesters and the police.

As a reminder, Canada sends 75% of its exports to the US, and the bridge usually handles 8,000 trucks a day, representing a quarter of all cross-border trade, or about C$500 million ($392.56 million) per day. About C$100 million worth of auto parts cross the border each day, according to Reuters.

But trade isn't the only factor: PM Trudeau has ulterior motives for wanting to crush the protesters and keep his mandates in place.

Despite the fact that Canadians are already among the most heavily vaxxed people on Earth.

But tell us again why mask mandates and other restrictions are necessary to prevent...more mask mandates and restrictions?

https://www.zerohedge.com/political/canadian-police-arrive-remove-freedom-convoy-protesters-ambassador-bridge

Ipsen plans sale of consumer health business for €350m

 Ipsen has started exclusive negotiations that could see its global consumer health business sold to fellow French pharma company Mayoly Spindler later this year.

If consummated, the deal would bring in around €350 million for Ipsen, leaving the company as a specialty pharma pure-play in cancer, rare diseases and neuroscience and ending its strategy of adopting a combined prescription and over-the-counter (OTC) medicines business model.

It marks a significant change in direction for Ipsen, which has spent several years of building up the consumer health business through the acquisition of products from Sanofi, Boehringer Ingelheim, and Poland’s Novascon,  the takeover of Italy’s Akkadeas Pharma – a specialist in probiotics and food supplements – and a licensing deal with Chinese nutritional products company McKin.

Ipsen’s consumer health range includes brands like diarrhoea remedy Smecta, Forlax for constipation and Ginkgo biloba supplement Tanakan, which recorded revenues of €226 million in 2021, up 8%. Ipsen’s specialty pharma business grew almost 13% to €2.6 billion last year.

“The combination of Ipsen’s and Mayoly Spindler’s respective…businesses will create a global consumer healthcare platform with a critical size and the capacity to support its growth,” said the company in a statement.

Privately-held Mayoly Spindler is a specialist in gastroenterology and dermato-cosmetic products that has set itself the target of becoming a top 10 European OTC medicines company in the next 10 years.

The deal – due to complete in the third quarter – will provide a cash injection for Ipsen as it tries to work through regulatory hold ups in the US and Europe for palovarotene, a rare disease therapy acquired via its $1.3 billion takeover of Clementia Pharma in 2019.

The company has just claimed its first approval for the drug in Canada – under the Sohonos brand name – as a treatment for the ultra-rare genetic disorder fibrodysplasia ossificans progressiva (FOP), but was forced to withdraw its marketing application for the drug in the US last summer after a request for more data.

Ipsen has also made no secret it is in a drive to replenish its pipeline as it faces erosion of its top-selling drug Somatuline (lanreotide), a therapy for acromegaly and neuroendocrine tumours, which accounted for €1.2 billion of its revenues last year.

The divestment follows an ongoing trend among pharma companies to divest their consumer health divisions, with GlaxoSmithKline due to spin out its joint venture with Pfizer into a new company later this year, and Johnson & Johnson announcing similar plans for its consumer health unit last November.

https://pharmaphorum.com/news/ipsen-plans-sale-of-consumer-health-business-for-e350m/

Show Will Go On for Cassava after FDA Denies Citizen Petition

 Shares of Cassava Sciences are up more than 5% in premarket trading after the U.S. Food and Drug Administration denied a Citizen Petition filed last year on behalf of short-selling clients who sought to suspend the company’s Alzheimer’s clinical trials.

Remi Barbier, president and chief executive officer of Texas-based Cassava Sciences, said the news was welcome but not surprising.

“We said from the outset that the allegations are false. I think the message may be that the FDA’s citizen petition privilege is not to be trifled with by stock market participants,” Barbier said in a statement.

In August, an attorney filed the Citizen Petition on behalf of two neuroscientists who claimed they doubted the research data being conducted by Cassava. The two men decided to short the company’s stock, betting that the share prices would fall when the data issues they claimed to see became public information. As BioSpace previously reported, the physicians argued that Cassava’s published research included images of experiments that appeared to have been manipulated using Photoshop or similar software. The petition sought to halt Cassava’s studies of its lead drug candidate, simufilam, which was advanced into Phase III trials in Alzheimer’s disease.

The August petition wasn’t the only filing made by the attorney representing the short sellers. They made multiple supplemental requests, including one made in November, alleging “wrongdoing” conducted by Cassava. 

“FDA has a duty to immediately halt the simufilam (PT1-125) clinical trials, conduct a rigorous audit of all the company’s research and clinical trial results, and report the agency’s findings to interested law enforcement and regulatory authorities,” the short sellers claimed.

In its response, the FDA said the petitions “do not purport to set forth all relevant factual information.” The FDA said the petition calls for the FDA to launch a fact-finding investigation, which is not under the purview of the Citizen Petition. The petition process currently only allows the regulatory agency to review or overturn regulations that the FDA has already issued.

“Issuing a response to your requests would appear to require FDA to publicly disclose information about an investigational new drug that, by law, FDA generally cannot publicly disclose,” Patrizia Cavazzoni, M.D., director of the FDA’s Center for Drug Evaluation and Research said in the response.

Cassava’s simufilam is an oral small molecule drug candidate designed to restore the normal shape and function of altered filamin A (FLNA) protein in the brain. When FLNA is altered, it disrupts the normal operation of neurons, leading to Alzheimer’s pathology, neurodegeneration and neuroinflammation. The drug is being assessed in two Phase III studies.

In December, the editors of Neuroscience announced that it could find no evidence to support claims of data manipulation in a 2005 paper authored by the company and its scientific collaborators. 

“In response to allegations of data manipulation in an article published in Neuroscience Vol 135, Issue 1, 2005, Pages 247–261, and following COPE (Committee on Publication Ethics) guidelines, the journal asked the authors for images of the original, uncropped Western blots from this study. After careful examination of these original materials, Neuroscience found no evidence of manipulation of the Western blot data or other figures of this publication,” the publication posted online, according to a statement from Cassava.

While the FDA denied the Citizen Petition, Cassava has also been under investigation by the U.S. Securities and Exchange Commission over the data claim allegations.

https://www.biospace.com/article/fda-denies-citizen-petition-to-halt-phase-iii-studies-of-cassava-sciences-alzheimer-s-drug/

Police begin clearing Canada trucker blockade

 Police have started to clear a blockade of the main crossing between Canada and the United States.

After days of protests by truckers against Covid rules at the Ambassador Bridge in Ontario, officers urged them to heed an injunction against the demonstration.

The vital trade route links Windsor, Ontario, with Detroit, Michigan.

Truckers' protests against Covid vaccine mandates are also ongoing at other border crossings and in Ottawa.

The self-styled "Freedom Convoy" movement was started by Canadian truckers opposed to a vaccinate-or-quarantine order for drivers crossing the border.

Friday's court order against the blockade was filed by the city of Windsor and the Automotive Parts Manufacturers' Association, which argued that it was losing as much as $50m ($39m; £29m) per day because of the convoy.


Following the injunction, Windsor Police put out a statement to "make demonstrators clearly aware that it is a criminal offence" to block the border crossing. The police added that a criminal conviction could lead to the seizure of vehicles and the inability to enter the US.

But hours later, crowds of people waving Canadian flags flouted the order and continued to occupy the bridge.

Police added on Saturday: "We urge all demonstrators to act lawfully [and] peacefully. Commuters are still being asked to avoid the areas affected by the demonstrations at this time."

Hundreds of other protesters continue to demonstrate in the centre of Ottawa, the nation's capital. Two other border crossings with the US are also being blocked by anti vaccine mandate protesters.

Prime Minister Justin Trudeau spoke with US President Joe Biden about the border blockades on Friday.

The week-long disruption to the bridge, which accounts for roughly 25% of US-Canada annual trade estimated to be worth $1.7bn (£1.2bn) a day, rocked the car manufacturing industry.

General Motors, Ford, Toyota and Honda plants have been forced to halt production and cancel work shifts due to parts shortages caused by the blockade.


https://www.bbc.com/news/world-us-canada-60361533#:~:text=Police%20have%20started%20to%20clear,an%20injunction%20against%20the%20demonstration.

Mainland China to Help Overwhelmed Hong Kong With COVID Fight

 China will help Hong Kong to cope with an expanding COVID-19 outbreak by providing testing, treatment and quarantine capacity, Chief Secretary John Lee said on Saturday, adding that there were no plans for a mainland-style lockdown for now.

Hong Kong and mainland China are among few places in the world still aiming to suppress every COVID-19 outbreak, but the Omicron variant has proven tough to keep under control.

Lee, Health Secretary Sophia Chan and Security Chief Chris Tang were part of a delegation who visited neighbouring Shenzhen on Friday and Saturday to discuss support measures with mainland Chinese officials.

The measures will give Hong Kong a breathing space as medical capacity becomes stretched https://www.reuters.com/world/asia-pacific/hong-kongs-zero-covid-quest-pushes-medical-facilities-brink-2022-02-11on all fronts, although there were no specific details of the plans and it was not clear how quickly they could be implemented.

"At the meeting we were all on the same wavelength," Lee told reporters on his return from Shenzhen. "All support will be provided. Rapid tests and help building isolation facilities are things we agreed on."

"There are no plans for a lockdown at this stage."

Lab personnel, hospital beds, protective equipment were included in the support potentially on offer, Lee said. Chinese officials have also promised to ensure supplies of vegetables and fresh produce to Hong Kong, after the city faced a shortage https://www.reuters.com/world/asia-pacific/hong-kong-leader-says-city-stick-with-dynamic-zero-covid-strategy-now-2022-02-08 of such items earlier this week when truck drivers who tested positive for COVID-19 were unable to bring them in.

Hong Kong reported a record 1,514 new COVID-19 cases on Saturday, up from Friday's 1,325 despite the most stringent social restrictions yet. Another 1,500 or so came out positive in preliminary tests which may be added to the count in the near future. Three more people died in the past 24 hours.

"This is the toughest battle against the virus of the past two years," Edwin Tsui, controller of the Centre for Health Protection, told reporters.

"Please stay at home. We need your cooperation."

Hospital beds for COVID-19 patients are already at around 90% occupancy, while isolation facilities were also nearing their maximum, authorities said.

Hundreds of thousands of people have been forced to test every day, including the elderly and children, queuing for hours in tightly packed lines outside overwhelmed testing centres.

University of Hong Kong epidemiologists say the number of infections could reach tens of thousands a day in a matter of weeks, posing a major risk for the city's elderly, many of whom are not vaccinated https://www.reuters.com/world/asia-pacific/hong-kong-vaccine-rates-spike-outbreak-shatters-covid-free-dreams-2022-02-10 after the city's success at keeping the virus at bay for much of the pandemic led to a sense of complacency.

Infections were recorded in some 42 elder care homes, Tsui said.

Some epidemiologists say only a full mainland-style lockdown for around two months could bring the infection count back to zero, but warn this would not be a definitive fix as Omicron could find its way back into the city again soon after.

In a pre-recorded interview with local broadcaster Now TV published late on Friday, Health Secretary Chan said she did not want to impose a lockdown and that it was preferable that residents "do it themselves" by staying at home.

Hong Kong has recorded more than 20,000 infections and just over 200 deaths since the start of the pandemic, far fewer than in most other places, but at significant economic and psychological cost.

Hong Kong is one of the world's most isolated large cities, with flights 90% down, and hardly any allowed to transit.

https://www.usnews.com/news/world/articles/2022-02-12/hong-kong-to-report-record-1-510-covid-cases-on-saturday-tvb

Coach defends skater Kamila Valieva, CAS to hold Sunday hearing on case

 The Russian coach of the 15-year-old figure skater embroiled in an Olympic doping scandal broke her silence to defend Kamila Valieva on Saturday, while the sport’s highest court said it would hold a hearing on Valieva’s Winter Games future on Sunday.

Coach Eteri Tutberidze said she was certain Valieva was “clean and innocent” in an interview with Russian state television after hugging her figure-skating prodigy, who trained again at the rink next to the Capital Indoor Stadium on Saturday afternoon.

Valieva’s future at the Winter Games will be decided by Monday afternoon Beijing time, after a hearing by the Court of Arbitration for Sport (CAS) on Sunday, CAS said in a statement on Saturday.

The figure skater’s Olympics hangs in the balance after the stunning revelation that she had tested positive for a banned heart drug before winning the team event on Monday, but it took more than six weeks before that positive result was reported.

Valieva is due to compete again on Tuesday in the women’s individual event.

Figure skater Kamila Valieva reportedly tested positive for a banned heart drug at the 2022 Winter Olympics.
Figure skater Kamila Valieva reportedly tested positive for a banned heart drug at the 2022 Winter Olympics.
AP

YOUNG ATHLETES

Valieva is one of the youngest athletes ever to have a positive test revealed at the Olympics, in a case that has prompted outrage from fans, athletes and anti-doping advocates around the world.

Earlier, Olympic officials said they would welcome an anti-doping investigation into the Russian doctors, coaches and family members in Valieva’s entourage.

Many have questioned the role of the adults around the teenage skater and the continuing scourge of Russian doping in international sports.

Senior International Olympic Committee (IOC) member Dick Pound told Reuters that Russia may need an Olympic “timeout” after the latest doping scandal.

The Kremlin – separately preoccupied with Western diplomatic wrath over a troop buildup near Ukraine – calls Valieva’s case a “misunderstanding.”

Rachael Denhollander, the first woman to publicly accuse former USA Gymnastics doctor Larry Nassar of sexual abuse, told Reuters the failed drug test was a reminder of how vulnerable young athletes remain.

“A child does not make a choice to take those kinds of medications unless they’re given to her by somebody who’s in authority,” Denhollander told Reuters.

“What we’re really seeing is the incredible damage that has come yet again to a child who has been under the control of adults who value her, not for who she is but for what she can produce for them.”

COACH ADDS HER VOICE

Tutberidze is known for raising a generation of Russian skaters with stellar but ephemeral careers. Her skaters are among the only women in the world who can successfully land quadruple jumps.

On Saturday, she added her voice to the growing cries from Russian officials over the delay in the figure skater receiving her positive drug test result.

“I hope our officials will not abandon us and defend our rights and prove our innocence,” Valieva’s coach Eteri Tutberidze told Russian state television.
“I hope our officials will not abandon us and defend our rights and prove our innocence,” Valieva’s coach Eteri Tutberidze told Russian state television.
REUTERS

More than six weeks went by between Valieva’s sample being taken on Dec. 25 and Feb. 8 when she was notified by a lab in Stockholm, Sweden that she had tested positive for the banned heart medication trimetazidine.

“It’s unclear why an athlete with a suspected doping on Dec. 25 was cleared to compete at the Olympics,” Tutberidze told Russian state television.

“Either it is an ill-fated confluence of circumstances, or it’s a very well-planned plan. I hope our officials will not abandon us and defend our rights and prove our innocence.”

The Russian Olympic Committee (ROC), the Russian figure skating federation and Russian anti-doping agency RUSADA have questioned the timeline.

The Doping Control Laboratory Karolinska University Hospital, in Stockholm, is accredited by the World Anti-Doping Agency (WADA).

RUSADA released a statement saying the laboratory had cited a spike in COVID-19, which impacted staff and quarantine rules, as the reason for the delay.

The lab’s director Anton Pohanka declined to comment.

On Saturday, the International Olympic Committee said the delay was a question for WADA, which could not be immediately contacted by Reuters.

Test results during the Games take between 24-72 hours for a result, depending on the kind of test, but the process during the Olympics is expedited given the urgent need for quick results with many athletes competing in several events.

While a six-week delay is unusual, there could be mitigating factors, said Jean-Pierre Verdy, the former director of testing at the French Anti-Doping Agency (AFLD), who helped bust several top names on the Tour de France.

“Between a sample’s delivery time, added to the analysis time and re-analysis time to confirm the presence of a specific substance, and the fact that you have to send the screenings to several labs to get external confirmation – and some labs don’t have that kind of experience – the delays can be long,” Verdy told Reuters.

https://nypost.com/2022/02/12/2022-winter-olympics-russia-coach-defends-figure-skater-kamila-valieva-cas-to-hold-sunday-hearing-on-case/