Diversified Healthcare Trust (Nasdaq: DHC) today announced changes to its Board of Trustees and executive leadership team, and other actions to address its near term capital needs, including DHC’s pending debt maturities.
Phyllis Hollis has been appointed as an Independent Trustee of the DHC Board, effective September 26, 2023. Ms. Hollis previously worked as an executive at an investment bank and has extensive experience in finance and executing capital markets transactions. Ms. Hollis will serve on DHC’s Audit Committee as well as its Compensation Committee, which she will chair.
Adam Portnoy, Chair of DHC’s Board, made the following statement:
"On behalf of the DHC Board, I am excited to welcome Phyllis as our newest Board member. Phyllis is a recognized industry veteran with substantial executive and finance experience. We look forward to drawing on her insights and perspectives as we consider alternatives to address DHC’s near term financing needs and generally oversee DHC’s path forward."
Pancreatic cancer Phase 2 trial of onvansertib + SoC in the second-line setting demonstrated greater efficacy vs. historical controls with ORR of 19% (vs. 7.7%) and mPFS of 5.0 months (vs. 3.1 months)-
- Pancreatic cancer biomarker discovery trial in refractory patients demonstrated tumor biomarker responseto onvansertib treatment as a single-agent -
- Based on positive data from both pancreatic trials and supportive preclinical data, a first-line pancreatic investigator-initiated trial is planned to evaluate the efficacy of onvansertib + SoC -
Small Cell Lung Cancer Program
- Preliminary data from small cell lung cancer Phase 2 trial in refractory patients with extensive stage disease demonstrate single-agent activity from onvansertib monotherapy -
- Company will hold a conference call today at 5:00 p.m. ET/2:00 p.m. PT
Cardiff Oncology will host a corresponding conference call and live webcast at 5:00 p.m. ET/2:00 p.m. PT on September 26, 2023. Individuals interested in listening to the live conference call may do so by using the webcast link in the "Investors" section of the company's website at www.cardiffoncology.com. A webcast replay will be available in the investor relations section on the company's website for 30 days following the completion of the call.
Excessive screen time may be taking more from children than their attention.
For the first time, researchers in Turkey have shown that blue light exposure can speed up the onset of puberty in male rats, demonstrating a potential link between smart device screens and early childhood development.
A joint team from Gazi University and Bilkent City Hospital in Ankara presented their work at the 61st Annual European Society for Paediatric Endocrinology Meeting in The Hague, as well as published recently in Frontiers in Endocrinology.
The new findings follow their previous study on blue light exposure in female rats, where early puberty was also observed.
“For the first time, we found a direct relationship between blue light exposure and early puberty in male rats,” said lead researcher Dr. Aylin Kılınç Uğurlu, of Bikent City Hospital. “Our findings align with our previous work on female rats, which also showed similar effects, thereby providing a more comprehensive view of how blue light may influence puberty both male and female rats.”
Eighteen male rats, aged 21 days old, were divided evenly into three groups — two of which were assigned either six or 12 hours of blue light exposure, while a third, the control group, maintained a 12-hour light-dark cycle with no blue light exposure from devices.
The same team from Turkey previously conducted a study with similar results on female rats, demonstrating a potential link between early puberty and excessive screen time in both young boys and girls.Getty Images Researchers saw the first signs of puberty “significantly earlier” in male rats exposed to blue light, compared to the control group.
“I want to emphasize that this is a rat study and direct results cannot be interpreted for humans. However, we provide an experimental foundation to further investigate the health consequences of ever-increasing screen time in modern society,” Uğurlu noted in a news release.
The researchers hope to continue the current study on blue light exposure in rats to better “understand its long-term effects on reproductive organ damage and fertility,” Uğurlu said. “Ultimately, this research could lead to preventative measures and contribute to the ongoing discourse on how modern lifestyles affect physiological development and long-term health.”
In a world that revolves around access to smart devices, experts have become increasingly concerned about the effects of this now ubiquitous technology — especially the impact on youth.
Blue light is already well-known todisrupt the circadian rhythmby suppressing the production of the sleep hormone melatonin, thus delaying sleep onset and encouraging groggier days. For teenagers in particular a lack of sleep can manifest as academic struggles andmore emotional troubles. The results suggest that young people need more routine and intervention strategies surrounding the use of smart devices.
President Biden, 80, slipped and nearly tumbled down a 14-step staircase while exiting Air Force One on Tuesday — just hours after it was revealed that the commander in chief is working with a physical therapist and using shorter stairs to avoid further trip-ups.
The near-miss occurred moments after Biden touched down at the Detroit Metro Airport, where he was greeted by United Auto Workers president Shawn Fain, Michigan Lt. Gov. Garland Gilchrist and US Reps. Debbie Dingell, Rashida Tlaib and Shri Thanedar, all Michigan Democrats, the clip shared by radio reporter Alex McLennon shows.
Despite the hair-raising moment, Biden recovered his footing and appeared unbothered by the gaffe.
Footage of the incident, however, quickly caught fire on social media — which was already smoldering from earlier reports that Biden has been doing balancing exercises in order to avoid more public spills as his team frets over polls showing that three-quarters of Americans think he is too old for a second term.
In addition to meeting with physical therapist Drew Contreras, the veteran politician has been spotted opting for sneakers rather than slippery dress shoes, and is using the shorter staircase to help him reach Air Force One’s flight deck.
President Biden joined striking members of the United Auto Workers on the picket line outside GM’s Willow Run Distribution Center in Bellville, Michigan.AFP via Getty Images
Some onlookers, however, jumped to Biden’s defense.
“Have you ever slightly stumbled walking down stairs in your life?” liberal influencer Brian Krassenstein scoffed.
“Does that mean you are bad at your job or should be fired?” he continued, before adding that “FDR was literally in a wheelchair throughout his presidency.
“I don’t understand the fixation of the GOP with Biden tripping. He’s an old man, he’s going to do that once in a while,” another observer shrugged.
Biden’s balance issues are likely related to arthritis in his spine and foot, the Axios report said Tuesday.
His condition has been under scrutiny in recent months following several troubling incidents — including when he stumbled and fell at the Air Force Academy in June.
Air Force One is a frequent site of Biden’s slips: He was foiled by the stairs up to the aircraft three times in March 2021 alone.
“[The reports are] an unfortunate pattern of media attempting to sensationalize something that has long been public,” White House spokesperson Andrew Bates said of the public’s ongoing interest in keeping Biden on his toes — literally.
“This isn’t new,” he insisted, “it was proactively and transparently disclosed.”
Despite his apparent confidence, the president seemed muddled at the strike meeting as well.
“I marched a lot of UAW picket lines when I was a senator since 1973. But I tell you what — first time I’ve ever done it in person,” he told the crowd in a video shared by Benny Johnson.
YS Biopharma Co., Ltd. (NASDAQ: YS) ("YS Biopharma" or the "Company"), a global biopharmaceutical company dedicated to discovering, developing, manufacturing, and delivering new generations of vaccines and therapeutic biologics for infectious diseases and cancer, today announced that it has enrolled the first subject in its Phase 3 clinical trial (the "Phase 3 Trial" or the "Trial") of the Company's PIKA Rabies Vaccine. The Trial, which will assess the safety, immunogenicity, and lot-to-lot consistency of the PIKA Rabies Vaccine, is expected to include an estimated 4,500 subjects in total.
GOP Senator Ted Cruz has speculated that Joe Biden will not be chosen as the Democratic nominee for 2024 and that the distinction will go to none other than Michelle Obama in a last minute Democratic National Convention decision.
“I think the odds are very significant that next summer at the Democrat national convention that the Democrat party will jettison Joe Biden and will throw him off the ticket, and they will parachute in instead, Michelle Obama to be their candidate,” Cruz told Sean Hannity.
“I think they’re gonna look to Michelle Obama as the savior to come in,” Cruz continued, adding “I think if that happens, that would be very, very dangerous.”
“And every time I see a Democrat or one of their puppets in the press beginning to point out the problems with Joe Biden – every time that happens, the chances of that go up and up and up,” Cruz added.
When Hannity asked if Michelle Obama even wants to run, Cruz reasoned that there are no other candidates that wouldn’t alienate certain Democratic voters.
Referring to Kamala Harris, Elizabeth Warren, Gavin Newsom, and Pete Buttigieg, Cruz noted that “If the Democrats pick any of those four, you tick off the other three and risk alienating their supporters.”
He continued, “I think Michelle Obama brings the Obama pedigree. She parachutes in with also the suit of armor of a First Lady with high positives and relatively low negatives. And I think they can justify to everyone who gets snubbed, ‘Well, look, we went with Michelle Obama instead.’”
“I don’t know if she wants it. But I do think it would be much more attractive to her to come in next summer and just campaign a couple of months to the general rather than having to spend two years campaigning vigorously on the ground,” the Senator further suggested.
Biophytis SA (Nasdaq CM:BPTS, Euronext Growth Paris:ALBPS), (Biophytis), a clinical-stage biotechnology company specialized in the development of therapeutics that are aimed at slowing the degenerative processes associated with aging and improving functional outcomes for patients suffering from age-related diseases, and Skyepharma, a French pharmaceutical company specializing in the formulation, development and production of pharmaceutical products, announce the signature of a partnership agreement for the production of regulatory batches of Sarconeos (BIO101) for severe forms of Covid-19, with a view to the submission of marketing authorization applications.
Based on the active ingredient produced by SEQENS, Skyepharma will develop finished product batches meeting the GMP (Good Manufacturing Practice) standards required for market access filings. The key stages in the production of Sarconeos (BIO101) will be entrusted to leading, innovative French partners meeting the highest standards of pharmaceutical quality. Pharmaceutical development work at the industrial stage will complete the information required for early access authorizations, particularly in France and Brazil.
