Target $14
Thursday, March 13, 2025
MeiraGTx Collaboration with Hologen AI to Expedite Phase 3 of AAV-GAD for Parkinson’s
MeiraGTx to receive $200 million in upfront cash consideration
- MeiraGTx and Hologen will form a joint venture, Hologen Neuro AI Ltd, with an additional $230 million committed capital from Hologen to fund 100% of the development of AAV-GAD for Parkinson’s disease through to commercialization, as well as other potential pipeline products
- MeiraGTx will enter into clinical and commercial supply agreements with Hologen Neuro AI Ltd to manufacture AAV-GAD and other locally delivered CNS genetic medicines
- Hologen will also fund a portion of MeiraGTx’s manufacturing operations and will own a minority stake in MeiraGTx’s manufacturing subsidiary
FDA Issues Clearance for ReWalk 7 Exoskeleton
Lifeward Ltd., (Nasdaq: LFWD) (“Lifeward” or the “Company”), a global leader in innovative medical technology to transform the lives of people with physical limitations or disabilities, announced today that the Company has received 510(k) FDA clearance for the newest generation of its personal exoskeleton device, the ReWalk 7. The seventh generation of the ReWalk, a wearable exoskeleton that allows individuals with spinal cord injury (SCI) to stand and walk again, includes a number of new features, as well as enhancements and upgrades.
DOGE Impact Remains Muted As National Jobless Claims Tumble
Following the initial surge in jobless claims in the DC area to start the year, things have slowed notably in the last two weeks (although last week saw a modest rise in the number of people filing for first time benefits)...
Source: Bloomberg
Overall, initial claims fell last week - with non-seasonally-adjusted claims now at their lowest since November
Source: Bloomberg
Meanwhile what the fuck is going on with NY jobless claims data?
Last week claims exploded higher in NY...
And this week they collapsed...
Continuing jobless claims remain range-bound for the last six months around the 1.875mm Americans level...
Source: Bloomberg
We wonder if the discrepancy between DOGE-driven layoffs and the lack of signal in the claims data is related to the buyouts offered to federal workers - which may preclude them from applying for unemployment benefits.
https://www.zerohedge.com/personal-finance/doge-impact-remains-muted-jobless-claims-slide
Putin Rejects US Temporary Ceasefire Plan, Appears In Military Fatigues
Russia has rejected the US-proposed 30-day ceasefire which came out of the Jeddah meeting with Ukraine, describing that it would only allow Ukrainian forces to regroup.
"This is nothing other than a temporary time-out for Ukrainian soldiers, nothing more. Our goal is a long-term peaceful resolution," Yuri Ushakov, a senior aide to Russian President Vladimir Putin, told Russian state television. "Our goal is a long-term peaceful settlement that takes into account the legitimate interests of our country and our well-known concerns. It seems to me that no one needs any steps that (merely) imitate peaceful actions in this situation," he said. He further expressed that it would "give nothing" to Russia.
This was the first official public response on the issue from the Kremlin, after it said Wednesday it was "studying" the proposal. President Trump’s special envoy, Steve Witkoff, is currently en route to Moscow to discuss the temporary truce proposal.
Ushakov says he has communicated Moscow's rejection of the 30-day ceasefire plan to Trump's national security adviser Mike Waltz.
None of this comes as a great surprise, given not only that Russian forces have the clear battlefield momentum and upper-hand, but back in January President Putin explained why he would never settle for any ceasefire that's temporary.
He had said at the time, "The goal should not be a short truce, not some kind of respite for regrouping forces and rearmament with the aim of subsequently continuing the conflict, but a long-term peace based on respect for the legitimate interests of all people, all nations living in this region."
The Russian leader had on Wednesday visited Kursk region for the first time since Ukraine's incursion there and holding of territory which began in August.
"Our immediate goal is as soon as possible to conclusively destroy the enemy entrenched on the territory of Kursk region," Putin said.
And the optics and symbolism were not missed on Russia's enemies, as Putin was dressed in military fatigues as he addressed top generals, which is a rarity.
President Trump has been warning of what could happen if Moscow doesn't come the negotiating table. "I can do things financially that would be very bad for Russia," Trump said earlier. "I don't want to do that because I want to get peace. I want to see peace and we'll see. But in a financial sense, yeah, we could do things very bad for Russia. It would be devastating for Russia."
But as Moon of Alabama highlights in fresh analysis, the meager 30-day truce offering which came out of Jeddah demonstrates weakness on the US side. Asia Times had predicted:
According to the latest from Riyadh, Ukraine says it is ready for a 30 day cease fire. If this is what Washington “extracted” from the Ukrainians, it is operationally meaningless. With Russia on the brink of winning in Kursk and elsewhere, the Russians won’t accept any such deal. If it is a ruse to allow the US to resume arms shipments to Ukraine, knowing Russia will reject it, the so-called peace initiative is a dead letter.
Meanwhile RT has featured the explanation and more context to Russia's rejection by political analyst Sergey Markov as follows...
Reasons why Russia to refuse a ceasefire (and especially anything deemed temporary):
1. A ceasefire would be exploited by the West and Ukraine to halt the advance of the Russian army, strip it of its initiative, supply the Ukrainian army with more weapons, continue extensive mobilization in Ukraine, and strengthen the repressive and anti-Russian nature of the Ukrainian political regime
2. The experience of the Minsk 1 and Minsk 2 agreements clearly demonstrates this pattern
3. The consistent dishonesty of Western politicians and media regarding the conflict, as well as their refusal to acknowledge their own and Ukraine’s culpability, strongly suggests that history will repeat itself
4. Russian President Vladimir Putin and other Russian officials have repeatedly stated that what Russia needs is lasting peace, not just a temporary ceasefire
5. The West cannot really be trusted
6. Russia is advancing. A ceasefire always benefits those who are retreating.
Core Producer Prices Tumbled Most Since COVID Lockdowns In February
Following yesterday's slower than expected rise in consumer prices, this morning we see producer prices following a similar path with Core PPI dropping by the most MoM since April 2020 (-0.1% MoM vs +0.3% exp), slowing the annual pace of change for producer prices to +3.4%...
Source: Bloomberg
Transportation Services was the biggest downside driver of Core PPI...
Source: Bloomberg
The headline PPI was unchanged MoM (considerably slower than the +0.3% expected)...
Source: Bloomberg
PPI summary: 0.3% increase in prices for final demand goods offset a 0.2% decline in the index for final demand services. The index for final demand less foods, energy, and trade services moved up 0.2% in February after rising 0.3% in January. For the 12 months ended in February, prices for final demand less foods, energy, and trade services advanced 3.3 percent.
PPI Final demand: The index for final demand goods increased 0.3% in February, fifth consecutive rise. Leading the February advance, prices for final demand foods jumped 1.7%. The index for final demand goods less foods and energy moved up 0.4 percent. In contrast, prices for final demand energy fell 1.2%.
Product detail:
Two-thirds of the February increase in the index for final demand goods is attributable to prices for chicken eggs, which jumped 53.6 percent.
The indexes for pork, fresh and dry vegetables, electric power, tobacco products, and carbon steel scrap also moved higher.
Conversely, prices for gasoline declined 4.7 percent.
The indexes for processed young chickens and for primary basic organic chemicals also decreased.
PPI Final demand services: The index for final demand services fell 0.2% in February, the largest decline since moving down 0.2 percent in July 2024. The February decrease can be traced to margins for final demand trade services, which dropped 1.0 percent. In contrast, prices for final demand services less trade, transportation, and warehousing rose 0.2 percent, while the index for final demand transportation and warehousing services was unchanged.
Product detail:
Over 40% of the February decline in prices for final demand services is attributable to margins for machinery and vehicle wholesaling, which decreased 1.4 percent.
The indexes for food and alcohol retailing; automobiles and automobile parts retailing; apparel, footwear, and accessories retailing; chemicals and allied products wholesaling; and residential real estate loans (partial) also moved lower.
Conversely, prices for inpatient care advanced 0.8 percent.
The indexes for hospital outpatient care and for machinery and equipment parts and supplies wholesaling also increased
Under the hood, Energy and Trade Services declined the most MoM...
Source: Bloomberg
Margin pressure remains on American corporations, although that pressure did ease a little last month...
Source: Bloomberg
Finally we highlight that, two-thirds of the February increase in the index for final demand goods is attributable to prices for chicken eggs, which jumped 53.6 percent.
And now egg prices are tumbling...
And energy prices are set to drag CPI and PPI even lower in the next month or so...
Source: Bloomberg
More disinflationary impulses to come...
https://www.zerohedge.com/political/core-producer-prices-tumbled-most-covid-lockdowns-february
Fiery But Peaceful: MSNBC Describes Violent Attacks On Tesla Dealerships As 'Protests'
by Steve Watson via Modernity.news,
MSNBC had its own ‘fiery but peaceful’ moment when anchors claimed that violent attacks on Tesla facilities are perfectly legal ‘protests.’
Attackers have put staff in danger and even set fire to Tesla dealerships and charging stations, but the MSNBC hosts were visibly annoyed that President Trump agreed the actions could constitute domestic terrorism.
One of them whined “you have this post claiming that protests at Tesla dealerships are illegal.”
MSNBC Host wants to “be clear” that attacks against Tesla are is “protests.” pic.twitter.com/7tUyAaZJYS
— Townhall.com (@townhallcom) March 12, 2025
Or maybe it’s because they are throwing Molotov cocktails at and shooting out the windows of Tesla dealerships.
Oh yeah, this is just a little ole, mostly peaceful protest pic.twitter.com/sxXTcL41BI
— ScrollofTruth (@ScrollofTruthIF) March 12, 2025
In one case explosives were even discovered at a dealership in Colorado.
Woman arrested after explosives discovered at Tesla dealership https://t.co/YaVMMFqZlk
— Fox News (@FoxNews) February 27, 2025
“Woman”?
NBC and CNN are spreading misinformation. The person who was arrested for vandalizing and bringing explosives to a Tesla dealership, is a MAN pretending to be a woman. pic.twitter.com/46A9LC5Ch0
— Libs of TikTok (@libsoftiktok) February 26, 2025
Leftist media lies are so transparent at this point.
When your team is burning down stores and trucks, that's not what good guys do. Maybe it's time to ask yourselves : "Are we really the good guys here?"
— ilaks (@ilaks) March 12, 2025
They’re not even trying anymore.
Violence isn’t a protest
— bigdog1969 (@bigdog19692) March 12, 2025
@MSNBC so if someone hates your reporting and sets your studios on fire, that’s only a protest?
— Ireene Almayda (@IreeneAlmayda) March 12, 2025
LOL…but doing wheelies on a rainbow crosswalk is a hate crime not a protest. https://t.co/BBkUt5kMe0
— Linda Eastwood (@EastwoodWolf) March 12, 2025
hmmmmmm….. pic.twitter.com/fSsj44w9df
— 🌟Lite Brite🌟 (@LiteBriteLite) March 12, 2025
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