Seaport Therapeutics, a Phase 2 biotech developing therapies for neuropsychiatric indications, filed on Friday with the SEC to raise up to $100 million in an initial public offering.
Seaport Therapeutics is a clinical-stage biotechnology company developing oral therapies for neuropsychiatric disorders, including depression, anxiety, and other central nervous system conditions. The company uses its proprietary Glyph platform, a lymphatic-targeting prodrug technology designed to improve oral bioavailability and reduce first-pass metabolism, to reformulate clinically validated mechanisms into differentiated product candidates. Its lead programs include GlyphAllo in Phase 2b for major depressive disorder and GlyphAgo in Phase 1 for generalized anxiety disorder, with additional preclinical candidates targeting depressive and related CNS disorders.
The Boston, MA-based company was founded in 2024 and plans to list on the Nasdaq under the symbol SPTX. Seaport Therapeutics filed confidentially on November 21, 2025. Goldman Sachs, J.P. Morgan, Leerink Partners, Citi, and Stifel are the joint bookrunners on the deal.
Hemab Therapeutics, a Phase 3-ready biotech developing blood coagulation disorder treatments, filed on Friday with the SEC to raise up to $100 million in an initial public offering.
Hemab is a clinical-stage biotechnology company developing antibody-based therapies for inherited bleeding and coagulation disorders. Its lead candidate, sutacimig (HMB-001), finished Phase 2 and is ready for Phase 3 for Glanzmann thrombasthenia and Phase 2 for Factor VII deficiency, while HMB-002 is in Phase 1/2 for Von Willebrand Disease. The company’s programs are focused on prophylactic subcutaneous treatments for rare disorders with limited existing options, and it is also advancing additional preclinical candidates in coagulation-related diseases.
The Cambridge, MA-based company was founded in 2020 and plans to list on the Nasdaq under the symbol COAG. Hemab Therapeutics filed confidentially on February 27, 2026. Goldman Sachs, Jefferies, and Evercore ISI are the joint bookrunners on the deal.
Rio Tinto (RIO) has attractedinterest from more than a dozen potential bidders for its U.S. assets that produce the critical mineral boron, which could fetch ~$2B in a sale, Bloomberg reported Friday.
WE Soda, the world’s largest producer of soda ash; Magris Resources, a Canadian mining investment firm; and U.S. Silica Holdings, one of the world's top producers of silica sand used in glassmaking and construction, are among the companies considering a purchase of Rio's (RIO) boron assets in California, according to the report.
Rio (RIO) has said its California operations meet about a third of global demand for refined boron, which is used in fertilizers as well as in high-tech applications such as heat-resistant glass and materials for renewable energy, and is a key to stabilizing permanent rare earth magnets.
The company's boron assets include a mine and processing operations in the Mojave Desert town of Boron, a refinery and shipping facility at the Port of Los Angeles, and its Owens Lake mining operation near the Sierra Nevada mountains.
On April 10, 2026, Valero Energy CorpVLO, the leading importer of Mexican crude oil, announced a significant reduction in its crude oil purchases, dropping to just one cargo this month compared to an average of 4 million barrels monthly last year. This decline is attributed to difficulties in restarting its Port Arthur, Texas, refinery, which suffered severe damage from a fire last month. The refinery is vital for processing imports and its downtime is notably impacting Mexico's Pemex, which relies on Valero for approximately 20% of its oil sales.
Valero Energy has a market capitalization of approximately $71.4 billion.
GF Score™: 74/100, indicating a solid overall performance relative to peers.
Insider activity shows a net sell of $2.0 million over the past three months, signaling potential caution among insiders.
Valero Energy's recent decision to cut back on crude oil purchases is a direct response to operational challenges stemming from the fire at its Port Arthur refinery. This facility is crucial for the company's operations, and the inability to restart key units has not only affected Valero's production capabilities but also has broader implications for its suppliers, particularly Pemex. The reduction in imports could lead to supply chain disruptions and may affect pricing dynamics in the oil market, especially given the reliance of Pemex on Valero for a significant portion of its sales.
Iran does not currently have the capacity to remove the landmines it planted in the Strait of Hormuz, The New York Times (NYT) reported.
According to a US source familiar with the matter, Iran cannot locate some of the landmines in the strait.
The speculation came ahead of upcoming negotiations between the US and Iran, with the status of the Strait of Hormuz as one of the key points in the talks.
In his latest episode, podcaster Joe Rogan lays out the massive financial motive behind the silencing of experts on zero-point energy and plasma tech, while his guest declares an apocalyptic convergence of UFO secrets, AI, and global chaos.
Rogan encourages listeners to confront a pattern the establishment would rather bury: scientists with access to game-changing space, nuclear, and advanced energy secrets are dying or vanishing at an alarming rate.
“People have to understand this missing scientist thing. It sounds a little conspiratorial. It sounds a little silly, a little tinfoil hatty,” Rogan explained, clarifying “Until you start thinking about the amount of money that would be lost if a breakthrough tech came around that revolutionized the way they distribute energy.”
🚨 Joe Rogan speaks on the missing scientists related to advanced technology
“People have to understand this missing scientist thing. It sounds a little conspiratorial. It sounds a little silly, a little tinfoil hatty.
He continues, “Breakthrough zero point energy breakthrough whatever that is that these people are working on. Plasma technology, whatever the fuck that is. You would lose if you’re in whatever business that would be competing with them. You’re going to lose so much fucking money. You’re probably going to go under. If you’re in the energy business, you’re going to… or he goes away, right?”
Rogan paints a vivid picture of the human cost: “Mystery around dead or missing scientists privy to space and nuclear secrets grows. Imagine being a scientist, you work so hard to figure out some amazing stuff that’s going to transform the human experience and then people kill you. Literally kill you like in a parking lot, one of those silenced guns.”
🚨 Joe Rogan speaks on the missing scientists related to advanced technology
“Mystery around dead or missing scientists privy to space and nuclear secrets grows.
Imagine being a scientist, you work so hard to figure out some amazing stuff that's going to transform the human… pic.twitter.com/3pYTDtxgeO
The comments land just as fresh scrutiny hit the ninth case in the growing list. Michael David Hicks, a longtime research scientist at NASA’s Jet Propulsion Laboratory who worked on the DART asteroid deflection project and planetary defense initiatives with direct national security implications, died at age 59. No cause of death was ever released publicly, and no autopsy record has surfaced. NASA and JPL have remained silent.
Others who have gone missing or died include astrophysicist Carl Grillmair, shot dead on his front porch in February 2026; NASA JPL senior scientist Frank Maiwald, who died in 2024 with no cause disclosed; aerospace engineer Monica Reza, who vanished while hiking in June 2025; retired Air Force Gen. William Neil McCasland, who disappeared in February 2026 after overseeing billions in classified space programs; and others tied to Los Alamos National Laboratory and MIT plasma fusion research.
As laid out in the reporting on the exploding pattern of deaths among experts guarding America’s most guarded programs, these individuals held knowledge that sits at the intersection of civilian space exploration and military applications—from hypersonic tracking to propulsion systems that could slash reliance on foreign energy and materials.
Rep. Tim Burchett has linked several cases directly to UFO-related knowledge and warned that the deaths send a clear message: people don’t want to talk about unidentified flying objects anymore because they are afraid.
He has added that the numbers in these specific research areas are “very high” and urged Congress not to trust the government on the matter.
Former FBI officials have noted the suspicious nature, pointing out such targeting of critical technology experts has echoes of Cold War-era espionage.
Duncan Trussell, Rogan’s guest on the April 9 episode, took the discussion further into territory that feels ripped from Terrence McKenna’s wildest predictions. “We are heading for the APOCALYPSE. This is some Terrence McKenna style pre-singularity shit,” Trussell declared. He pointed to scientists relating to the UFO stuff going missing, the breakneck rise of AI, congressmen and officials openly discussing aliens and demons, and escalating wars in the Middle East. “It’s like everything converging into an apocalyptic river,” Trussell noted.
🚨 "We are heading for the APOCALYPSE. This is some Terrence McKenna style pre-singularity shit."
Duncan Trussell just said it on today’s Joe Rogan.
Scientists relating to the UFO stuff going missing. The emergence of AI. Congressmen and government openly talking about aliens… pic.twitter.com/QTCfaMC4xU
The timing is impossible to ignore. These conversations explode publicly right as President Trump continues demanding the full release of UFO and UAP files long buried by layers of bureaucracy. The very experts who could illuminate breakthrough propulsion, gravity manipulation, or zero-point energy technologies are being removed from the board—whether through outright hits or convenient “disappearances.”
Congress is already probing the string of incidents involving scientists working on space, gravity, and advanced energy tech. National security voices warn of foreign adversaries targeting American talent at facilities like JPL and Los Alamos. Yet the official response remains the same: silence, no comments, no transparency.
Rogan’s point about motive cuts to the core. If zero-point or plasma breakthroughs could upend trillion-dollar energy distribution models, entire empires built on scarcity and control would collapse overnight. The deep state doesn’t just protect secrets—it protects the cash flow that keeps Americans dependent.
Trussell’s apocalyptic framing resonates because the pieces are aligning perfectly: suppressed energy tech, vanishing experts, AI accelerating beyond human oversight, open congressional talk of non-human intelligence, and global conflicts that feel engineered to distract. This doesn’t feel like random chaos, rather appears to be convergence.
The American people have every right to demand answers. Taxpayer-funded programs at NASA, JPL, and Los Alamos produced these breakthroughs. The public funded the research. Now the public watches the researchers vanish while the same gatekeepers who buried the files refuse to explain why.
The Federal Reserve is asking major US banks for details about their exposure to private credit following a surge in redemptions from the funds and a rise in troubled loans in the industry, according to people with knowledge of the matter.
The queries by Fed examiners are intended to assess the level of stress in the private credit industry and the potential for it to spill over to the wider financial system, said the people, requesting anonymity to discuss the work.
