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Friday, March 29, 2019

Ligand partner Seelos up on pipeline advancement

Seelos Therapeutics (NASDAQ:SEELprovides an update on recent pipeline developments and corporate highlights.
Corporate Highlights
The Company successfully transitioned into a publicly traded company on Nasdaq by completing its reverse merger with Apricus BioSciences on January 24.
Also, Seelos has acquired two exciting new programs: SLS-005, focused on orphan diseases in the CNS, and SLS-007, a family of peptidic inhibitors directed toward alpha-synuclein aggregates in Parkinson’s disease (PD).
Update on Pipeline Development
SLS-002 (intranasal racemic ketamine): The Company plans to initiate phase I study of SLS-002 in patients with post-traumatic stress disorder (PTSD) at imminent suicide risk (suicidality).
SLS-005 (trehalose): Seelos expects to dose first patient with Sanfilippo Syndrome with Trehalose in a phase IIb trial in 2Q.
SLS-007 (Peptidic inhibitors): Seelos expects to begin to evaluate this peptide-based approach targeting the NACore (nonamyloid component core) in PD in a proof of concept, in-vivo delivery of SLS-007 in a PD transgenic mice model in 2Q.
Shares are up 33% premarket.

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