Sangamo Therapeutics presented new preclinical data demonstrating significant (greater than80%) reduction of tau expression in the nonhuman primate brain following administration of zinc finger protein transcription factors. Tau pathology is strongly linked to the progression of several neurodegenerative diseases, called tauopathies, including Alzheimer’s disease. The data, reported in a podium presentation at the 14th International Conference on Alzheimer’s & Parkinson’s Diseases held in Lisbon, Portugal, described the effects of tau-targeted ZFP-TFs delivered with adeno-associated viruses in the mouse and nonhuman primate brain.
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.