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Thursday, March 28, 2019

Aptinyx to present detailed results from Phase 2 NYX-2925 at APSS meeting

Aptinyx announced an upcoming poster presentation highlighting the detailed results from a recently completed Phase 2 study of NYX-2925 for the treatment of painful diabetic peripheral neuropathy. The poster presentation will take place at the American Pain Society Scientific Meeting in Milwaukee, Wisconsin on April 4.”While we announced in January that the study did not meet the primary endpoint in the total study population, the findings from the detailed analysis provide a strong scientific foundation for advancing the development of NYX-2925 for the treatment of chronic pain,” said Norbert Riedel, president and chief executive officer of Aptinyx. “The mechanism of NYX-2925 is particularly relevant to the central pain perception and processing that occurs as chronic pain persists, and we are very encouraged to see that those patients in the study who had DPN for a longer period of time showed a robust and clinically significant treatment benefit from NYX-2925 across multiple endpoints. Not only is this a critical finding based on our mechanism, but it also suggests the potential of NYX-2925 to address a major unmet medical need. Importantly, the detailed results from the study also inform future development of NYX-2925 in painful DPN. We look forward to presenting the detailed analysis at the APS Scientific Meeting.”

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