WuXi AppTec Research Service Division and BioSolveIT today launched a new virtual chemical space called GalaXi.
Largely built from WuXi AppTec’s library of novel drug-like
scaffolds, GalaXi offers access to billions of compounds to drug
discoverers around the world. Due to a carefully selected building block
supply and proven chemistry, the GalaXi space consists of molecules
that can be quickly synthesized on demand.
Novel molecular entities are in high demand to combat diseases such
as cancer, bacterial and viral infections, as well as illnesses of the
central nervous system. Over decades, traditional compound libraries
containing millions of compounds have been collected and curated.
However, many more compounds, though synthetically feasible, have
traditionally been inaccessible due to physical and informatic
limitations. The GalaXi space is a combination of WuXi AppTec’s
chemistry expertise and BioSolveIT’s cutting edge software technologies,
resulting in a chemical space housing billions of virtual molecules
that can be mined within minutes and synthesized within a few weeks.
The game-changing element of this system lies in the design of a
virtual chemical space that is both vast and practical in its synthetic
feasibility. Navigation of GalaXi relies on clever algorithms that
account for the chemicals and chemistry expertise to turn ideas into
matter. Not only is the GalaXi orders of magnitude larger than
traditional libraries, but also turn-around times and costs of custom
synthesis are drastically reduced.
‘We used to be able to screen millions of compounds in seconds, but
access to billions of compounds in minutes is just amazing,’ said Dr.
Steve Yang, Executive Vice President and Chief Business Officer of WuXi
AppTec. ‘This is exactly what our clients need. The pressure on research
to come up with novel ideas is indeed enormous, both in terms of time
and cost. With GalaXi we take a large step forward in improving the
productivity of new drug discovery and bring new medicines to patients
faster.’
https://www.marketscreener.com/WUXI-APPTEC-CO-LTD-44403583/news/WuXi-AppTec-Research-Service-Division-and-BioSolveIT-Introduce-GalaXi-a-Vast-New-Chemical-Space-o-29367643/
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