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Tuesday, January 14, 2020

Alexion to launch study of Ultomiris in ALS

Alexion Pharmaceuticals (ALXN -2%plans to launch a late-stage study, CHAMPION-ALS, this quarter evaluating Ultomiris (ravulizumab-cwvz) in patients with amyotrophic lateral sclerosis (ALS).
The primary endpoint of the 350-subject study will be the change from baseline in a scale called ALSFRS-R.
Ravulizumab is a complement inhibitor currently approved in the U.S. for atypical hemolytic uremic syndrome and paroxysmal nocturnal hemoglobinuria.

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