Nano cap Catalyst Biosciences (CBIO +6.3%) is up, albeit on only 94K shares, in apparent response to preliminary results from a Phase 2b clinical trial
evaluating dalcinonacog alfa (DalcA) in patients with severe hemophilia
B [factor IX (FIX) levels typically 1 – 5%]. The data will be presented
next week at the European Association for Hemophilia and Allied
Disorders (EAHAD) Annual Congress in The Hague, The Netherlands.
Per the abstract (OR07), treated patients showed
FIX levels between 16% and 27% at day 29. No anti-drug antibodies were
detected and no thrombotic (blood clotting) or bleeding events occurred
during the study.
Dalcinonacog alfa is a recombinant FIX variant with 22x greater potency and longer half-life compared to wild- type FIX.
https://seekingalpha.com/news/3536396-catalyst-bio-up-6-on-positive-dalca-data
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