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Wednesday, January 29, 2020

Satsuma Pharma rallies on encouraging data on lead candidate

Thinly traded micro cap Satsuma Pharmaceuticals (STSA +10.7%) is up on below-average volume, a modest 64K shares, adding to yesterday’s 30% pop, also on light volume.
After Tuesday’s close, it announced the publication of Phase 1 data on lead candidate STS101 (dihydroergotamine or DHE) nasal powder for the acute treatment of migraine in Headache, The Journal of Head and Face Pain. 
The early-stage, open-label, crossover study assessed the safety and pharmacokinetics of STS101, Bausch Health Companies’ (BHC +0.3%) Migranal (dihydroergotamine mesylate) nasal spray and DHE administered via intramuscular (IM) injection in healthy volunteers.
The authors concluded that STS101 showed a favorable tolerability profile and delivered greater DHE plasma concentrations than both Migranal and IM DHE.
A Phase 3 clinical trial, EMERGE, is in process with topline data expected in H2. The primary endpoints are pain freedom and freedom from the most bothersome symptom at hour 2 post dose.
Selected migraine-related tickers: Amgen (AMGN +1.1%), Eli Lilly (LLY +1.1%), Teva Pharmaceutical Industries (TEVA +1.2%), Allergan (AGN +0.1%), Axsome Therapeutics (AXSM +0.5%), Biohaven Pharmaceutical Holding (BHVN -8.5%)
https://seekingalpha.com/news/3535842-satsuma-pharma-rallies-on-encouraging-data-on-lead-candidate-up-11

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