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Tuesday, February 18, 2020

Bellerophon up on positive INOpulse data

Thinly traded nano cap Bellerophon Therapeutics (NASDAQ:BLPH) jumps 61% premarket on robust volume in reaction to positive topline data from a 16-subject Phase 2 clinical trial, PULSE-PHPF-002, evaluating INOpulse in patients with pulmonary hypertension associated with pulmonary fibrosis.
Acute treatment with INOpulse reduced pulmonary vascular resistance (PVR) by 21% with increased benefit on dose escalation, a primary endpoint.
Mean pulmonary arterial pressure (PAP), another primary endpoint, dropped 12%.
No new safety signals were observed.
A Phase 3 trial is next up.
INOpulse is a drug-device combination system that delivers pulsed doses of nitric oxide.

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