The American Thoracic Society issued guidelines suggesting Covid-19
patients with pneumonia get doses of the antimalarial drug
hydroxychloroquine if all of the following apply: a) shared
decision-making is possible, b) data can be collected for interim
comparisons of patients who received hydroxychloroquine (or chloroquine)
versus those who did not, c) the illness is sufficiently severe to
warrant investigational therapy, and d) the drug is not in short
supply,” the Thoracic Society said
The use of hydroxychloroquine has been hotly debated.
President Trump has promoted its use on an experimental basis and Gov. Andrew Cuomo has agreed to provide it to thousands of seriously ill patients in New York hospitals in combination with Zithromax.
Critics have criticized the promotion of using the drug based on limited or anecdotal evidence.
The Thoracic Society said its guidelines are based on input from an
international task force comprised of doctors from medical centers that
are currently treating COVID-19 patients.
The medical group said evidence about the impact of
hydroxychloroquine is “contradictory” but it is worth experimenting with
during a public health crisis to treat very sick patients.
“We believe that in urgent situations like a pandemic, we can learn
while treating by collecting real-world data,” said Dr. Kevin Wilson,
chief of Guidelines and Documents at the American Thoracic Society.
“There are in vitro studies that suggest that hydroxychloroquine and
chloroquine have activity against SARS-CoV-2019, the virus that causes
COVID-19,” Wilson said.
But he also said several controlled trials from China and France “all
have serious flaws and inconsistent findings. ….Thus, the bottom line
is, whether hydroxychloroquine and chloroquine confer benefits to
patients with COVID-19 are unanswered questions.”
https://nypost.com/2020/04/06/medical-group-backs-giving-hydroxychloroquine-to-coronavirus-patients/
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