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Monday, June 8, 2020

Aimmune’s Palforzia shows durable effect in study

Aimmune Therapeutics (AIMT +3.6%) announces positive data from a follow-on study to its Phase 3 PALISADE trial of peanut allergy product Palforzia [peanut (Arachis hypogaea) allergen powder-dnfp].
At year 2, patients dosed daily showed ongoing immunomodulation and higher rates of desensitization that increased over time compared to non-daily-dosed patients while experiencing lower rates of adverse events. 80% of these patients who underwent a food challenge demonstrated desensitization to 2,000 mg of peanut protein (~14 kernels), higher than the non-daily group.
The FDA approved Palforzia in January.

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