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Wednesday, June 17, 2020

Repare Therapeutics files for upsized IPO

Repare Therapeutics (RPTX) has filed a preliminary prospectus for its IPO of 10M common shares at $18 – 20 per share.
Two days ago, it filed the same for an initial public offering of ~7.4M shares at $16 – 18.
The Cambridge, MA-based biotech develops precision oncology treatments based on synthetic lethality (SL), an approach to drug development focused on genomic instability, including DNA damage repair. SL pertains to a deficiency in either of two genes that is tolerated in cells, but leads to cell death when both genes are present. The company employs its proprietary, genome-wide, CRISPR-enabled SNIPRx platform to identify and develop highly targeted therapeutics for tumors that contain a mutation in one gene of an SL pair, making them prime candidates for intervention by targeting the other gene in the pair.
SL-related tickers: IDEAYA Biosciences (NASDAQ:IDYA), GlaxoSmithKline (NYSE:GSK)
https://seekingalpha.com/news/3583977-repare-therapeutics-files-for-upsized-ipo

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