Findings from a Phase 1 single ascending dose trial indicate the low dose of FX201, an intra-articular gene therapy candidate for osteoarthritis (OA), was generally well-tolerated
Two of five patients (40%) treated with FX201 in the low-dose, single ascending dose cohort reported substantial improvement in pain out to Week 24
No evidence of systemic biodistribution of FX201 in plasma or shedding in urine or at the injection site was observed in any patient
Longer term follow-up data from the low-dose cohort will be presented at ASGCT on May 11
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