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Tuesday, June 15, 2021

Novavax's COVID-19 Vaccine, Flu Shot Co-administration Preserved Efficacy, Likely 'Viable Strategy'

  • Novavax Inc (NASDAQ: NVAX) announced its experimental COVID-19 vaccine remained effective when coadministered with an approved flu shot.

  • Researchers are interested in studying coadministration and the associated safety & efficacy of giving multiple vaccines to a person during one visit to ease logistics and help patients catch up on missed vaccinations, especially amid the pandemic.

  • The company released the results from a sub-study it conducted as part of its late-stage clinical trial of NVX-CoV2373 in the U.K.

  • The 431 participants enrolled in the sub-study received an approved seasonal influenza vaccine, with about half the participants administered NVX-CoV2373, while the rest received a placebo.

  • The company said vaccine efficacy was 87.5% compared to 89.8% in the main study.

  • Despite the "modest decrease," antibodies against the spike protein were reported as over three-fold higher than levels found in blood samples of people who received both vaccines.

  • The news comes hours after Novavax announced that its protein-based COVID-19 vaccine was found to be over 90% effective overall and offered 100% protection against moderate and severe disease in a Phase 3 trial.

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