Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19

 Luo, Peng MS^a; Ding, Yuanfang MS^b; He, Yuan PhD^c; Chen, Dafeng PhD^d; He, Qing MS^c; Huang, Zufeng MS^a,b; Huang, Shian^a,∗; Lei, Wei PhD^a,c,d

^DOI: doi: 10.1097/MD.0000000000027759

Abstract

A global public health crisis caused by the 2019 novel coronavirus disease (COVID-19) leads to considerable morbidity and mortality, which bring great challenge to respiratory medicine. Hydrogen-oxygen therapy contributes to treat severe respiratory diseases and improve lung functions, yet there is no information to support the clinical use of this therapy in the COVID-19 pneumonia.

A retrospective study of medical records was carried out in Shishou Hospital of Traditional Chinese Medicine in Hubei, China. COVID-19 patients (aged ≥ 30 years) admitted to the hospital from January 29 to March 20, 2020 were subjected to control group (n = 12) who received routine therapy and case group (n = 12) who received additional hydrogen-oxygen therapy. The clinical characteristics of COVID-19 patients were analyzed. The physiological and biochemical indexes, including immune inflammation indicators, electrolytes, myocardial enzyme profile, and functions of liver and kidney, were examined and investigated before and after hydrogen-oxygen therapy.

The results showed significant decreases in the neutrophil percentage and the concentration and abnormal proportion of C-reactive protein in COVID-19 patients received additional hydrogen-oxygen therapy.

This novel therapeutic may alleviate clinical symptoms of COVID-19 patients by suppressing inflammation responses.

https://journals.lww.com/md-journal/Fulltext/2022/03040/Hydrogen_oxygen_therapy_alleviates_clinical.1.aspx