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Thursday, August 4, 2022

GreenLight Biosciences, Samsung Biologics complete 1st commercial-scale engineering run for mRNA Covid vax

 

  • GreenLight’s messenger RNA production process is transferable to large-scale equipment and CMO facilities​

  • Technology transfer and scale-up from lab bench to Samsung’s commercial facility was completed in seven months

  • GreenLight’s mRNA synthesis reaction had a titer of 12g/L at a commercial scale and produced 650g of mRNA

  • The mRNA synthesis reaction was achieved without the need for customization, using standard equipment for Contract Development and Manufacturing Companies (CDMO)

  • Commercial-scale run has demonstrated production—in a single facility—of both Drug Substance and LNP formulation, allowing the production of bulk Drug Product

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