Horizon Therapeutics plc (Nasdaq: HZNP) today announced new data that indicate KRYSTEXXA (pegloticase) injection with weekly oral methotrexate effectively treats uncontrolled gout without compromising kidney function. These findings are presented as part of the American Society of Nephrology (ASN) Kidney Week, Nov. 3-6, 2022.
“Given that one in four adults with moderate-to-severe chronic kidney disease is impacted by gout, addressing the underlying cause of disease without compromising kidney function is paramount,” said Abdul Abdellatif, M.D. F.A.S.N., adjunct assistant professor, Baylor College of Medicine Nephrology Division, and Kidney Hypertension Transplant Clinic of CLS Health. “These data are encouraging and suggest that KRYSTEXXA with methotrexate effectively addressed the systemic burden of uncontrolled gout and did not lead to renal function decline in patients with mild-to-moderate chronic kidney disease.”
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