New analysis of Phase 2a JANUS clinical trial showed atacicept reduced immune complex levels in patients with IgA nephropathy (IgAN)
Atacicept is the first therapeutic to show reduction in all of the three first hits of IgAN pathogenesis – serum galactose-deficient IgA1 (Gd-IgA1), anti-Gd-IgA1, and now immune complex levels
Final results from the Phase 2 clinical trial of MAU868 versus placebo showed MAU868 was well tolerated and demonstrated clinically meaningful BK antiviral activity through 36 weeks in kidney transplant patients with BK viremia
Vera Therapeutics, Inc. (Nasdaq: VERA), a late-stage biotechnology company focused on developing and commercializing transformative treatments for patients with serious immunological diseases, today announced new clinical data presented on the Company’s two product candidates, atacicept in immunoglobulin A nephropathy (IgAN) and MAU868 in kidney transplant. These data were presented in poster and oral presentations, respectively at the American Society of Nephrology (ASN) Kidney Week 2022 Annual Meeting, held November 3-6, 2022 in Orlando, Florida.
The poster presentation on atacicept included a new analysis of previously presented clinical data from the Phase 2a JANUS clinical trial evaluating atacicept in patients with IgAN that showed atacicept reduced immune complex levels in patients with IgAN. Atacicept is the first therapeutic to show reduction in all of the first three hits of IgAN pathogenesis – serum galactose-deficient IgA1 (Gd-IgA1), anti-Gd-IgA1, and now immune complex levels. The oral presentation on MAU868 included final results from the Phase 2 clinical trial of MAU868 versus placebo to treat BK Virus (BKV) in kidney transplant patients that showed MAU868 was well tolerated and demonstrated clinically meaningful BK antiviral activity through 36 weeks in kidney transplant patients with BK viremia.
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